<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28592

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMNQTKDSEQTEPLAHSMPQSQDLPNGTASDNINDSVSVVEDQEVVVAEENKSPIDQPMEEDSVNPATVFTIRLRQSKANLMHKMSVPELCRNFSAVSWCGKLNAIACAAETCARIPSSTANPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPTSCPRALLIANFHGRVTIWTQPSQGPANLVRDASCWRREHEWRQDIAVATKWLSGVSPYRWLSSKSSATPDSKLTFEEKFLSQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPNQKDSTPRWFHTSKGLLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVTPGPGNGFQSCPMTSTKSGVPPHIPPNWDGFAPLAAYLFCWQDHLLSLAKQGKKLTEKNIGDSVPLYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPYDPDEGPTITGWRVQRWESSLEQVVLHPIFGNPTSSMGGQPPMQTVWQSKVDLSILPTDDFRNHRSPTIGMATDVQKVSELISDKSKRVNFDPFDLPSDVRTLARIVYSAHGGEIAIAFLRGGVHIFSGPNFEQVDNYQITVGSAIAAPAFSSTSCCSASVWHDTINNYTILKIIRVLPPPVPISQAKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSVQHRQQYGPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGRGIESALIDPTQFVPELWQASGETLSNIDSETMAVEPALVPCVQAYVDAILDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNMVASPTQSSATPATSQGGQNGSTSSMGTVQLQTWVQGAIAKISNTTEGGSNPTPNPISGPSSFMPISINTGTFPGTPAVRLIGDCQFLHRLCQLLLFCFFFRRTQIPRYMGAANRTNDSNTQKSNAPASGKVEEIAKPVSAVAKSEDGLTGRAGQLISGPKGGEEAPSGRSRLGSGNAGQGYTFEEVKVLFMMLMELCRRTSTLQHPLPISQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPSEEWNRRNMFGGPWSDPDDIDCANDQPKIVCSDPLDLSSTEHCDAYDGTHRLWPRKRRMSERDAAFGLNSSVGLGAYLGIMGSRRDVVTATWKTGLEGVWYKCIRCQRQTSAFTSPASTTSPSQSSRELWWISRWAYGCPMCGGTWVRVV
Length1245
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.08
Grand average of hydropathy-0.227
Instability index50.78
Isoelectric point6.04
Molecular weight135675.77
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblPlants

GO - Biological Function
GO - Biological Process
circadian regulation of gene expression	GO:0032922	IEA:EnsemblPlants
positive regulation of plant-type cell wall cellulose biosynthetic process	GO:2001011	IEA:EnsemblPlants
positive regulation of systemic acquired resistance	GO:1901672	IEA:EnsemblPlants
regulation of cell wall pectin metabolic process	GO:1902066	IEA:EnsemblPlants
regulation of ethylene-activated signaling pathway	GO:0010104	IEA:EnsemblPlants
regulation of jasmonic acid mediated signaling pathway	GO:2000022	IEA:EnsemblPlants
regulation of long-day photoperiodism, flowering	GO:0048586	IEA:EnsemblPlants
regulation of transcription, DNA-templated	GO:0006355	IBA:GO_Central
response to osmotic stress	GO:0006970	IEA:EnsemblPlants
root development	GO:0048364	IEA:EnsemblPlants
trichome branching	GO:0010091	IEA:EnsemblPlants
trichome papilla formation	GO:1905499	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28592
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     959.74|     200|     361|     298|     499|       1
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  298-  492 (328.71/206.23)	........GIMAGDAI.I..TDSGAMHVAGVPI....VNPSTIVVWEVTPG..PGN......G...F..QSCPM.........................TSTKSGVPPHIPP......NWDGFA.PLAAYLFC.WQDHLLSLAKQ...GKKLTEKNIGDS...VP.LYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPYDPDEGPTITGWRVQRWESSLEQVVLHPI..FGNPT.......SSMGGQ
  661-  846 (225.50/138.37)	........GVDWWDAVgC..TQSAAED..GIVS....LN.SVIAVLDA..............D...F..HSLPS.........................VQHRQQYGPSLDRikcrllEGSNAQ.EVRAMVLD.MQARLL.LDML...GRGI.ESALIDPtqfVPeLWQASGETLSNIDSETMAVEPALVPCVQAYVDAI.LD..LASHFITRL...RRYAS.....FCRTLASHAVTAGTGSNRNMVASPTqsSATPA.......TSQGGQ
  856- 1068 (183.46/114.23)	VQLQTwvqGAIAKISN.T..TEGGSNPTPN.PI....SGPSSFMPISINTGtfPGTpavrliGdcqFlhRLCQLllfcfffrrtqiprymgaanrtndsNTQKSNAP..ASG......KVEEIAkPVSAVAKS..EDGLTGRAGQlisGPKGGEEAPSGR...SR.L..........................GSGNAGQGYTFEEV.KVLFMMLMELCRRTSTLQHPLP......ISQVGSSNIQVRLHYI..DGNYTvlpevveASLG..
 1069- 1230 (222.07/138.22)	PHMQN.............mpRPRGA.DAAGLLLreleLHPPS.EEWNRRNM..FG.......G...P..WSDPD.........................DIDCANDQPKIVC......S.DPL..DLSSTEHCdAYDGTHRLWPR...KRRMSER...DA...AF.GLNSSV.GLGAYLGIMGSRRDVVTATWKTGLEGVWYKCIRCQRQTSAFTSPASTTSPSQSSREL....WWISRW................................
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28592 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGSNRNMVASPTQSSATPATSQGGQNGSTSSMG
2) MNQTKDSEQTEPLAHSMPQSQDLPNGTASDNINDS
821
1
854
35










Molecular Recognition Features






MoRF SequenceStartStop




NANANA