<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28589

Description HATPase_c domain protein
SequenceMAQKIDFNALRARTMGSGNDEEAVTVDTRGLISKVLARYSGKWTVLREMIQNAADANATKVTIKFETLPSTTVPLPPAADESTLIKHTISNHTLKRLLISNNGLPFSEKDWARLKRIADGNPDETKIGAFGVGFYSVFDDCEEPFVSSGKEAMAFYWKGNALFTRRLQLDEDANPETTFVLDYRNDTSPIPSLMQLCQFLSSSLTFVSLEGIELWLDDWNLLRLTKKTAPSVNLSIPRDIETKTPQGLMKIQNVTREVAQVDASWMRVIEWNPNASIFREGLRDTTGSLRTFFSKLTGQSAPEKPARPELQDKSTDSGEMTQTLTASVFLHINTASLQASVSQSLSSELERATRKPPPKRSTIAILTPSYDTTLASGASGLQSEVLSSILPSKGGRVFIGFPTHQTTGLNAHISAPSVIPTVERESIDLNTRYISKWNLEMLRAAGIVCRIAWTAEMASIKARISSGKESSKSMKVRKDDIAGVLPEAIHTAKQFVFRESTPSSLLGQTIEDAFWTCNKSASIEVLSTCGVIQSHQIRLAPKDLSFMDSIPVLPDEFYSGAREFVKKLTDFGLVTDITVSDIKQELETTTLRSSQAAEFLPWLGQRAASGQLDLYSIQSLLSVAVANEEDESSPQNRLIVFGSIDSYLSPQKIPVNLPVPPTVAPFKFTKSLGKQELEALGWTELQIVPWVRWLVCNSANRNILPLDQDITKSPSFSAQVLPVLSKQWEYLSQTAKQSVITQLQAHTVIPTKLGMKMPPETYFSSVRLFDDLPVIHGLNGVKEKFLAALGVRKTVELGVIFERLLDTTEAPDGPNNNQRKWSHVDLIRYLASVRDDIPANDIKRLKNTSLCTAEQSDGSGNSDLKAANRKRYKIFELFEPKDSLRALGLPIIEWPGRYQPSSNEGRFLSMLGLRSFPSASELIQIMAKAAADGNWVLHTKAMSYYIAEFHTSGYAMFDCGTVAVPFLPVEGSQGLTVPSKCFTDDGATLFGFAILRTDLHPHASKFGVKQHPALSECIDCLMRQPPSTKRDARVVFKYLAGRVSELSGRDIDRVGSAQVVPVTTTQDEMEKKVVRRVAPRLCYLGDGEDYKDIFDFVDFGQEANLFLMAVGSKREPTKVEIARMLVKEPARISASFQSADKYLKLLRTLAEHVSTLKKDRELYQEMKRSAFLLASRDITSLAQEQAAKDDHLSDDEEEDQSIKEWTLTVAKDAVVVDDFQSFNLFKEHILAAPQEEMLENFYQSLGAQPLSGLVEERAHWGAVAADQRPAAKLQKLISERSRLFLHDQSPDLIRHDVRWLEKHLQVRVVHSISLTRSLKGRRISHTQKRSAIITQQGRDWLLWICPGKYDLYEISQALVHLILVRPKLHSTLTLEMLLKTDLLELKARGYNVERILKQKAHEARMAEDRRQKQLEEERQRLQEREAAWAKEQAQIQAQPHQVQDEREQLMPGDFPDSPSGKNSTRDIQPDTPDQTQDRRPRGFFANLSKRFGLEGNRSPFNAVNGESSQPSRSESSETATPPPPYSAEDPQKTRSEAPVTVNSPHRLQSELLSAIQACRPHGSSDVYSRPETNQITEKKSYCDEKPSHDLEFVATLACGIHVLFVKNLPDRSQFLAKNSVGINVFASMLMDCAGVFSLRSDILSIFYDPGGKTIAFNRAGSVFCNYFYFQQLHEKQLLANPTADRADALVYWWVILCHELAHNLVGDHSSAHSYYTESFVAQYFPKITAKLASAAISDEFQSEKHFSDGDLMAGTPDASMEEILWRSPPHVQMMGGYLHSNNILFYFAESPFFDPTSNNASLAIQANYNEAFRHFVETREAFEGRLKTMQGLEFVVSYDPIQAAAQPDGRFAHEPSNIWVIRKQNRRKRTGLEDEVVVLSTYFIVGDCIYMAPSVASVVGNRILSAVTSLTSLLKTASTLPTFTPSHGHTYMPPALKQADASQPGTQSQQSKENTPLPDADAAGKASLVGSSQVVGTGSNLQDTRTLAESFNLLRRYGEEFMDEHPLVGEPGSFILSRVNDTDRTSAAKPPAPAAKVGTPQVRVDTPGKVSEKGATPSGSEENKMRKKKTKVGN
Length2074
PositionHead
OrganismAspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.08
Grand average of hydropathy-0.364
Instability index48.46
Isoelectric point6.49
Molecular weight230899.09
Publications
PubMed=22045919

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28589
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.36|      31|      50|     275|     309|       1
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  275-  309 (45.70/35.90)	ASIFregLRDTTGSLRTFFSK.LTG..QSAPEKPArPE
  326-  359 (44.66/23.35)	ASVF...LHINTASLQASVSQsLSSelERATRKPP.PK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.35|      29|      50|    1452|    1481|       2
---------------------------------------------------------------------------
 1452- 1481 (49.41/29.00)	GDfPDSPSGKNSTRDIQPDTPDQTQD.RRPR
 1505- 1534 (46.94/23.00)	GE.SSQPSRSESSETATPPPPYSAEDpQKTR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.60|      14|     405|      38|      53|       4
---------------------------------------------------------------------------
   38-   53 (22.87/18.50)	RYSGKWTVlrEMIQNA
  432-  445 (26.73/14.95)	RYISKWNL..EMLRAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.30|      22|     403|    1210|    1246|       7
---------------------------------------------------------------------------
 1187- 1208 (38.51/15.27)	AKDDHLSDDEEEDQSIKEWTLT
 1210- 1231 (36.79/45.48)	AKDAVVVDDFQSFNLFKEHILA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.38|      17|      19|    1406|    1422|       8
---------------------------------------------------------------------------
 1406- 1422 (26.91/14.79)	AEDRRQKQLEEERQRLQ
 1427- 1443 (29.47/16.85)	AWAKEQAQIQAQPHQVQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.88|      27|     403|     371|     430|       9
---------------------------------------------------------------------------
  381-  407 (48.71/79.71)	LQSEVLSSIL...PSKGGRVFIGFPTHQTT
 1547- 1576 (43.17/ 8.97)	LQSELLSAIQacrPHGSSDVYSRPETNQIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     166.16|      45|      49|     791|     838|      10
---------------------------------------------------------------------------
  791-  835 (72.31/37.41)	VRKTVELGVIFERLLDTTEAPD..GPNNNQRKW..........SHVDLIRYLASVRD
  842-  885 (60.13/33.65)	IKRLKNTSLCTAEQSDGSGNSD..LKAANRKRY..........KIFELFEPKDSLR.
  887-  931 (33.72/14.28)	......LG......LPIIEWPGryQPSSNEGRFlsmlglrsfpSASELIQIMAKAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.11|      49|      54|     141|     194|      13
---------------------------------------------------------------------------
  141-  194 (77.50/65.29)	CEepFVSSgkeAMAFY.WKGNALFT...RRLQLDEDANPETTFVLDYRNDTSPIPSLM
  197-  249 (73.62/47.48)	CQ..FLSS...SLTFVsLEGIELWLddwNLLRLTKKTAPSVNLSIPRDIETKTPQGLM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28589 with Med6 domain of Kingdom Fungi
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