<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28563

Description Uncharacterized protein
SequenceMAAFPASLNRPARVRAQRRRISAHSAVSAAAAVAVAATARGMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTENLVQQIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPAAXXXXXXXXXXXXXXXXXXXXLARAAAASDRCPLQPKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMDGPRRPPSFPILMALLPPLWQAGTVAPGGKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQQRGMGGQQAPPGLGPILEDQARPSQNLLQLRPPQSQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGTASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI
Length776
PositionUnknown
OrganismMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Cercopithecinae> Macaca.
Aromaticity0.05
Grand average of hydropathy-0.233
Instability index60.38
Isoelectric point9.38
Molecular weight79259.28
Publications
PubMed=22002653

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28563
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     182.61|      30|      30|     650|     679|       1
---------------------------------------------------------------------------
  398-  428 (40.98/ 7.35)	GLAPTAQPGAPSMDgP.RRPPSFPILMALL..PP
  589-  617 (44.01/ 8.45)	GGQQAPPGLGPILE.D.QARPSQN.LLQLR..PP
  652-  683 (56.70/13.06)	GTASGPPPPGPILR.P.QNPGANPQLRSLLlnPP
  684-  711 (40.93/ 7.33)	PPQTGVPPPQASLH.HlQPPGA.P...ALL.pPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     182.97|      38|     345|     358|     395|       2
---------------------------------------------------------------------------
  296-  332 (53.48/13.60)	S.GATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAV
  358-  395 (78.20/23.83)	GVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAP
  714-  739 (51.30/12.69)	GLG.......QPQL..GPPLLHPPPAQSWP...AQLPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.06|      41|     406|     122|     175|       3
---------------------------------------------------------------------------
   82-  125 (69.93/50.49)	LPAIEYFNGGPPAETDFGgdyGGTQYSLVVFNTVDCAPESYVQ....C
  139-  183 (66.13/27.03)	LDGIKFMGGGGESCSLIA...EGLSTALQLFDDFKKMREQIGQthrvC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      79.98|      18|      24|     487|     504|       6
---------------------------------------------------------------------------
  487-  500 (15.20/ 7.33)	...........LTTLGPLFR...NSRMV
  501-  525 (18.93/10.99)	QFHF...tnkdLESLKGLYRimgNGFAG
  526-  550 (19.58/11.63)	CVHFphtapceVRVLMLLYS...SKKKI
  559-  576 (26.28/18.21)	QSGF.......VNGIRQVIT...NHKQV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28563 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAASDRCPLQPKQPVPLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAPGSGLAPTAQPGAPSMDGPRRPPS
2) HKQVQQQKLEQQQRGMGGQQAPPGLGPILEDQARPSQNLLQLRPPQSQPQGTVGASGATGQPQPQGTAQPPPGAPQGPPGTASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMD
273
573
418
774










Molecular Recognition Features






MoRF SequenceStartStop




1) MSNSNAGRRSCDALPAAYARKMAASQQQASAASS
1
34