<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28521

Description U-box kinase family protein
SequenceMFERLNSFESIIMAVVSSMPATIQRTGSVSSVRDVRGEIEEEPNQIVVDEVICVAVSKDVKESKLNLIWAIQNSGGKKICILFVHVPATMIPLMGAKFPASSLKDQEVRAYREMERQNVHKTLDEYLRICQRMGVRAEKLHIEMENIEKGIIELISQHGIRKLIMGAASDKNYSRRMMDLRSRKAIYVCEQAPSSCHIQFICKGHLIHTRDRSLDERNVEVASPLLQQGPNSVRPSRSQSITLGQNHRTNSISSSQELFRRVRSANDGMTASITTNSSPVDNEGFSTPRNRRGTEVSSDESDRLSRTSPSGLSTFSDSTIDPTLTPYSVAESCENASDLTLSHLIKDEDLRHLSPPSVLDGGVNDTLYDQLEQAMSEANNATRHAYQETFRRGKAEKDAIEAIRRAKASESLYTDELNLRKMAEEELRKEKEELESVTSQRDKVNEELRLAVDLKSSLESQLASSEVMIQELEQKIISAVELLQSYKNERDELQIQRDNALREAEDLRKKQGEGSSTHVPQLFSEFSFSEIEEATSNFNPSLKIGEGGYGNIYKGLLRHTEVAIKILHANSMQGPLEFQQEVDVLSKLRHPNLITLIGACPESWSLVYEYLPNGSLEDRLACKDNTHPLSWQTRIRIAAELCSALIFLHSSKPHSIVHGDLKPSNIILDGNLVSKLSDFGICRVLSNYENSSNNNTQFWKTDPKGTFVYMDPEFLASGELTPKSDVYSFGIILLRLLTGRPALGITKEVKYAVDTGKLTSLLDPLAGDWPFVQAEQLARLALRCCEMNRKSRPDLHSDVWRILDAMRASSGGTNSFGLSSEGPHQPPSYFICPIFQEVMRDPHVAADGFTYEAEAIRGWLDSGHDASPMTNSTLSHQNLVPNRALRSAIQDWLQSH
Length896
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.06
Grand average of hydropathy-0.455
Instability index49.87
Isoelectric point5.76
Molecular weight100377.12
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28521
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.44|      11|      47|     670|     681|       1
---------------------------------------------------------------------------
  670-  681 (17.18/13.01)	GNLVSKlSD...FGI
  718-  731 (17.27/ 8.16)	GELTPK.SDvysFGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.15|      44|      48|     389|     436|       2
---------------------------------------------------------------------------
  389-  435 (64.37/53.30)	TFRRGKAE.........KDAIEAirrAKASESLYTDELNLRKMAEEEL....RKEKEELE
  438-  494 (55.79/33.28)	TSQRDKVNeelrlavdlKSSLES...QLASSEVMIQELEQKIISAVELlqsyKNERDELQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     206.87|      66|     535|     254|     351|       7
---------------------------------------------------------------------------
  254-  351 (96.07/77.00)	SSQELFRRVRSANDGMTASI.TTNSSPVDNEGFSTPrnrrgtevssdesdrlsrtspsglstFSDSTIDPTLtpysvaESCENASDL...TLSH..LIKDEDLR
  791-  826 (42.13/14.14)	SRPDLHSDVWRILDAMRASSgGTNSFGLSSEGPHQP....................................................................
  836-  886 (68.67/34.32)	..QEVMRDPHVAADGFT.............................................YEAEAIRGWL......DSGHDASPMtnsTLSHqnLVPNRALR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.22|      19|      19|     513|     531|       9
---------------------------------------------------------------------------
  513-  531 (33.50/17.52)	EGSSTHVPQL.FSEFSFSEI
  533-  552 (29.72/14.87)	EATSNFNPSLkIGEGGYGNI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28521 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LIKDEDLRHLSPPSVLDGGVNDTLYDQLEQAMSEANNATRHAYQETFR
2) RNVEVASPLLQQGPNSVRPSRSQSITLGQNHRTN
3) RSANDGMTASITTNSSPVDNEGFSTPRNRRGTEVSSDESDRLSRTSPSGLSTFSDSTID
344
217
263
391
250
321










Molecular Recognition Features






MoRF SequenceStartStop




NANANA