<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28510

Description "Mediator of RNA polymerase II transcription subunit 8, putative"
SequenceMEGELVQQPQPQQQERLNQAVQQQLNLEQVKTRAISLFKAISRILEDFDAYGRTNTNPKWQDILGQYSMVNLELFNIVDDIKKVSKAFIVYPKNVNAENATILPVMLSTKLLPEMETEDTLKRDQLLQGMQNLPIATQIDKLKARIDMIAAACEGAEKVLADTRKAYCFGTRQGPAIAPTLDKGQAAKIQEQENLLRAAVNVGEGLRIPGDQRHITASLPMHLADAFTVNESAQSFPDGSSNNVYMKNTPLSSNSMGGQNSLLQTSGSQLLGRSAASPSAATSATSFDNTTASPIPYANSPRSTTNMMNTPSPQQQTPQPQPQQLTAQQQQQQRQKLMQQLPQQQQQQLLAQQQYRQSAMQQGLGQLHGQHQMQFSPQLGHQQFQGRQLSSAHMQHSIGQSQLNQGNQMTRLNQFSGPANSALFSAAQTTPNTQMIPNISAGITSQSLLPRMQFGLSGNNPQRSHPSHMLSDQMFNMGGGNPGGMMSIQQQQQQQQQQQQQHSSQGAFGGMASNAQNLQSGMMTLQNAQQNHPNFTQQRQQNQQ
Length544
PositionHead
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.04
Grand average of hydropathy-0.736
Instability index53.71
Isoelectric point9.13
Molecular weight59994.50
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28510
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     414.35|     131|     159|     239|     388|       1
---------------------------------------------------------------------------
  239-  388 (206.14/66.20)	GSSNnvymkntpLS.SNSMGGQNsllQTSG...SQLLgrSAASPSAAT...SATSFDNTTASPIPY......ANSP.RSTTNMMntPSPQQ.QTPQPQPQQLTAQQQQQQRQKlmQQLPQQQQQQLLAQQQYRQSAMQQGLGQLhgQHQMQFSPQLGHQQFQGRQ
  399-  544 (208.20/48.61)	GQSQ........LNqGNQMTRLN...QFSGpanSALF..SAAQTTPNTqmiPNISAGITSQSLLPRmqfglsGNNPqRSHPSHM..LSDQMfNMGGGNPGGMMSIQQQQQQQQ..QQQQQHSSQGAFGGMASNAQNLQSGMMTL..QNAQQNHPNFTQQRQQNQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.72|      26|      40|     119|     146|       2
---------------------------------------------------------------------------
  119-  146 (40.87/35.65)	DTlkRDQLLQGMQNLP.IATQIDKLK.ARI
  162-  189 (39.85/27.53)	DT..RKAYCFGTRQGPaIAPTLDKGQaAKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.69|      16|      44|      11|      28|       3
---------------------------------------------------------------------------
   11-   28 (23.99/16.39)	PQQQERLNQavQQQLNLE
   58-   73 (30.70/15.56)	PKWQDILGQ..YSMVNLE
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28510 with Med8 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AFTVNESAQSFPDGSSNNVYMKNTPLSSNSMGGQNSLLQTSGSQLLGRSAASPSAATSATSFDNTTASPIPYANSPRSTTNMMNTPSPQQQTPQPQPQQLTAQQQQQQRQKLMQQLPQQQQQQLLAQQQYRQSAMQQGLGQLHGQHQMQFSPQLGHQQFQGRQLSSAHMQHSIGQSQLNQGNQMTRLNQFSGPANSALFSAAQTTPNTQMIPNISAGIT
2) QSLLPRMQFGLSGNNPQRSHPSHMLSDQMFNMGGGNPGGMMSIQQQQQQQQQQQQQHSSQGAFGGMASNAQNLQSGMMTLQNAQQNHPNFTQQRQQNQQ
226
446
444
544

Molecular Recognition Features

MoRF SequenceStartStop
NANANA