<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28501

Description Heat shock 70 kDa protein
SequenceMATKEGKAIGIDLGTTYSCVGVWQNDRVEIIPNDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRRFSDESVQNDMKLWPFKVVPGPAEKPMIVVNYKGEEKKFAAEEISSMVLIKMREVAEAFLGHPVKNAVVTVPAYFNDSQRQATKDAGAISGLNVLRIINEPTAAAIAYGLDKKASRKGEQNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVSEFRRKNKKDISGNARALRRLRTACERAKRTLSSTAQTTIEIDSLFEGIDFYATITRARFEELNMDLFRKCMEPVEKCLRDAKIDKSHVHEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGDEKVQDLLLLDVTPLSLGLETAGGVMTTLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVFEGERARTKDNNLLGKFELTGIPPAPRGVPQINVCFDIDANGILNVSAEDKTAGVKNKITITNDKGRLSKEEIEKMVKDAEKYKAEDEEVKKKVEAKNSIENYAYNMRNTIKDEKIGGKLSHEDKEKIEKAVEDAIQWLEGNQMAEVDEFEDKQKELEGICNPIIAKMYQGGAGGDVPMGDGMPGGGGGASNGTGSGAGPKIEEVD
Length653
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.06
Grand average of hydropathy-0.433
Instability index34.79
Isoelectric point5.28
Molecular weight71538.32
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28501
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.60|      25|      27|     533|     559|       1
---------------------------------------------------------------------------
  494-  524 (24.21/12.06)	..SAEDKTAGVKNKIT..itndkgrlSK.EEIEKMV
  525-  541 (22.21/ 7.11)	KDA.EKY........K.........aED.EEVKKKV
  544-  579 (31.18/21.28)	KNSIENYAYNMRNTIKdekiggklshEDkEKIEKAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.92|      36|      41|     303|     343|       2
---------------------------------------------------------------------------
  303-  343 (58.41/43.44)	TR.ARFEELNMDLFR.....KCMEPVEKCLRDAkidksHVHEVVLVG
  346-  387 (50.51/28.28)	TRiPKVQQLLQDFFNgkelcKSINPDEAVAYGA.....AVQAAILSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.00|      18|      21|      37|      54|       3
---------------------------------------------------------------------------
   15-   32 (19.59/10.39)	....TTYSCVGVWQNDRveIIP
   37-   54 (32.67/22.10)	NR..TTPSYVAFTDTER..LIG
   59-   77 (24.74/15.00)	NQvaMNPQNTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.36|      30|      49|     412|     444|       6
---------------------------------------------------------------------------
  412-  444 (47.68/34.55)	GGVMTTLIPrntTIPTKKEQIFSTYSDNQPGVL
  462-  491 (54.68/31.95)	GKFELTGIP...PAPRGVPQINVCFDIDANGIL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28501 with Med37 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGAGGDVPMGDGMPGGGGGASNGTGSGAGPKIEEVD
618
653










Molecular Recognition Features






MoRF SequenceStartStop




1) ASNGTGSGAGPKIEEVD
637
653