<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28501

Description Heat shock 70 kDa protein
SequenceMATKEGKAIGIDLGTTYSCVGVWQNDRVEIIPNDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDAKRLIGRRFSDESVQNDMKLWPFKVVPGPAEKPMIVVNYKGEEKKFAAEEISSMVLIKMREVAEAFLGHPVKNAVVTVPAYFNDSQRQATKDAGAISGLNVLRIINEPTAAAIAYGLDKKASRKGEQNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDNRMVNHFVSEFRRKNKKDISGNARALRRLRTACERAKRTLSSTAQTTIEIDSLFEGIDFYATITRARFEELNMDLFRKCMEPVEKCLRDAKIDKSHVHEVVLVGGSTRIPKVQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILSGEGDEKVQDLLLLDVTPLSLGLETAGGVMTTLIPRNTTIPTKKEQIFSTYSDNQPGVLIQVFEGERARTKDNNLLGKFELTGIPPAPRGVPQINVCFDIDANGILNVSAEDKTAGVKNKITITNDKGRLSKEEIEKMVKDAEKYKAEDEEVKKKVEAKNSIENYAYNMRNTIKDEKIGGKLSHEDKEKIEKAVEDAIQWLEGNQMAEVDEFEDKQKELEGICNPIIAKMYQGGAGGDVPMGDGMPGGGGGASNGTGSGAGPKIEEVD
Length653
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.06
Grand average of hydropathy-0.433
Instability index34.79
Isoelectric point5.28
Molecular weight71538.32
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28501
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.60|      25|      27|     533|     559|       1
---------------------------------------------------------------------------
  494-  524 (24.21/12.06)	..SAEDKTAGVKNKIT..itndkgrlSK.EEIEKMV
  525-  541 (22.21/ 7.11)	KDA.EKY........K.........aED.EEVKKKV
  544-  579 (31.18/21.28)	KNSIENYAYNMRNTIKdekiggklshEDkEKIEKAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.92|      36|      41|     303|     343|       2
---------------------------------------------------------------------------
  303-  343 (58.41/43.44)	TR.ARFEELNMDLFR.....KCMEPVEKCLRDAkidksHVHEVVLVG
  346-  387 (50.51/28.28)	TRiPKVQQLLQDFFNgkelcKSINPDEAVAYGA.....AVQAAILSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.00|      18|      21|      37|      54|       3
---------------------------------------------------------------------------
   15-   32 (19.59/10.39)	....TTYSCVGVWQNDRveIIP
   37-   54 (32.67/22.10)	NR..TTPSYVAFTDTER..LIG
   59-   77 (24.74/15.00)	NQvaMNPQNTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     102.36|      30|      49|     412|     444|       6
---------------------------------------------------------------------------
  412-  444 (47.68/34.55)	GGVMTTLIPrntTIPTKKEQIFSTYSDNQPGVL
  462-  491 (54.68/31.95)	GKFELTGIP...PAPRGVPQINVCFDIDANGIL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28501 with Med37 domain of Kingdom Viridiplantae
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