<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28489

Description U-box kinase family protein
SequenceMDRIQRIQEGDESKRTRHSSSSVVALAIKGNKKSKYVVQWALNKFVPEGMIIFKLIHVHAGIVGVPTPMGNMLPISQVRDDVAAAYKKEIECETNQMLLPFKQMCEQRKVHVEVVVIESDDVASAVAEEVTKYAVTKLVVGASTGGLFKSKHKGMSAKISVCTPRFCTVYAVSKGKLLIRPSDVQIDESITDDTSEISFSSSSSSNYTSTTQTDSGSVASYAALHSSSLATQRFQALSSMNQNLLSTNPSLNETNHSRGQSIDLGRGNVATSSARNSDFDRGLSRASSFRSIVSDTDTWIYDQISLKDAPLTSKLASPNRQENFNLELEKLRIELRHAQGMHAVAQTENIDASRKLNELSKRRSGESMKMKEIIAKEEVAKELARQEIEKYEAAAREASYLKECAEREASERKETELKAIRAAKEKDKLEDALSGSTPQYRKFTWDEIVSATSSFSEDLRIGMGAYGMVYKCTLHHTTVAVKVLHSAGISQSKQFQQELEILSRIRHPNLLLLLGACPDHGCLVYEYMENGSLEDRLFQKNSTTPIRWFDRFRVAWEIASALSFLHSSKPQPIIHRDLKPANILLGGNLVSKIGDIGLSTVLNSDELSTMYKDTAPVGTLSYIDPEYQRSGLISTKSDVYAFGLVMLQLLTAKPATALTHVVETAIEDGNLTDILDPKAGLWPFQETLDLARLALSCAELRRRDRPDLLDHVLPTLERLKEVADRAHHSASMVAIKPKPPNHFICPILQDVMDDPCVAADGYTYDRKAIEKWLEEKDKSPMTNIPLPHKILIPNYTLLSAILEWKSKEI
Length809
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.06
Grand average of hydropathy-0.335
Instability index43.97
Isoelectric point6.76
Molecular weight90017.59
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28489
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.65|      15|      19|     191|     205|       2
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  191-  205 (25.14/13.47)	TDDTSEISFSSSSSS
  213-  227 (25.51/13.77)	TDSGSVASYAALHSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.92|      30|      70|     262|     291|       3
---------------------------------------------------------------------------
  262-  291 (50.85/33.72)	IDL..GRGNVATSSARNSDFDRGLSRASSFRS
  333-  364 (45.07/29.09)	IELrhAQGMHAVAQTENIDASRKLNELSKRRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.78|      23|     472|     297|     319|       4
---------------------------------------------------------------------------
  297-  319 (40.60/24.93)	DTWI..YDQISLKDAPLTSKLASPN
  770-  794 (38.18/23.03)	EKWLeeKDKSPMTNIPLPHKILIPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.63|      13|      14|     390|     402|       5
---------------------------------------------------------------------------
  390-  402 (21.05/14.97)	KYEAAAREASYLK
  406-  418 (20.58/14.46)	EREASERKETELK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28489 with Med32 domain of Kingdom Viridiplantae
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