<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28482

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMNPMKESEAEAEAAATVNDPMMEEEEVEAGTVFDISLEQSPSTSLHKITVHESMRSNFSAVAWCAKLNVIACATETCVNGIPRSSVNPWFWIPIHIVIPERPTEIAAFNVVADSSLDSVQSIQWSPICCPRALLIANFQGRVTIWTQPSRGPPNLVIDTNCWQREHEWRQETAVVTKWLSGASPYRWLSSKASAPTDSKSTFVEKFISQQPETSARWPKFLCVCSVSQSGKVQLHWSQRPPTQNATPPKWFCTSKGLIECGPSGIIAADAIITDSGMLHVAGVLAFSPATVIVWVVLPGQGNGLEFSPKTSITTSAPLSPPNWIGFAPLPAFLFSWQDQSIPLHCSTVSNFSAYVSSEAAPSTQCCGVAGVAFDPTRGGSVIAAVVVEGKYMSPHDPDESLSITGWRVQRWESSFQPVVLNPIFGSMDGNPPMRTVWESKVDISIPATDDKSKGIHFNPFDLPKYLGTLARVVFSAQGGEIAVAFFQGRVRIFSGSNFEPVTNYEINVGSSISVPAFSATSCCSASVWHDTSKGEAMLKIIRVLPPPFPIGQEKATSSTWEHAISERFWFSLLVGVDWWDVVGCTQRAAEEGIVSVNGVIAVLDADFHSLPTAQHRQQYCLGLDMIKCRLLVGSNAQEVRATVLDMQARVLLDMLGKGIESALINPSALLPDPWQASEEILSNFDMEEMAVEPELTPCIQAYVDSVIDLASHLITRLRHYAKIFRTLANQAVTVASGSTSGGVPNLTLNPSISGPSSLMLISINTGTFPGTPAVRLIGDCHFLHRLCQLLFFCFFFKRSQLARYKSGLRRTAETSLVRSNDGQTGRDRQIVPGSKGGEEPSPGPVRLGNGNAGQGYSVEEVKVIFQVLLDLCRRTSGLQHPLPVSQVGSSNIQVQLHYIEGSYTVLPEVVEASLGPYMQNMPRLGDADDTGLLLRELQLHPPAEEWHQLNMFVRPCTDSNDTPKPFRSNPLDSRSLESNDIDYGTNGLRPKKRRMIERDAAFGLNTSLGLGAYLGIMGSRRDVITTSWKTGLEGVWYKCIRCMRQTSAFTSLGSANIPHQNERESWWVSRWAYSCPMCGGRWVRVV
Length1086
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.08
Grand average of hydropathy-0.095
Instability index46.29
Isoelectric point5.98
Molecular weight119059.24
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28482
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.70|      25|      27|     198|     222|       1
---------------------------------------------------------------------------
  170-  187 (23.47/ 9.39)	QETAVVTKWLS..GAS.PYRW.....
  198-  222 (47.00/27.19)	SKSTFVEKFISQQPET.SARWPKFLC
  227-  252 (43.22/24.33)	SQSGKVQLHWSQRPPTqNATPPKWFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     202.23|      58|     110|     306|     373|       2
---------------------------------------------------------------------------
   39-   81 (60.37/32.73)	QSPSTSL..........................................HKI...TVHES...MRSNFSAVAwcakLNVIACATETC.VNGI
   85-  149 (46.40/21.74)	.............SVNPWF.WIPIHIVIPERPTeiaafnvvadssldsvQSIqwsPICCPralLIANFQGRV....TIWTQPS.........
  306-  371 (95.46/77.58)	FSPKTSIttsaplSPPNWIgFAPLPAFLFSWQD................QSI...PLHCS...TVSNFSAYV....SSEAAPSTQCCgVAGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     195.68|      61|      68|     388|     452|       3
---------------------------------------------------------------------------
  388-  452 (105.61/72.44)	EGKYMSPHD.PDE..SLSITGWRVQRWE...SSFQPVVlnPIFGSMDGNPpmRTVWESKV..DISIPATDDKS
  453-  521 (90.07/50.82)	KGIHFNPFDlPKYlgTLARVVFSAQGGEiavAFFQGRV..RIFSGSNFEP..VTNYEINVgsSISVPAFSATS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.87|      43|      69|     800|     844|       4
---------------------------------------------------------------------------
  800-  844 (71.92/54.50)	QLARYKSGLRRTAETSLVRSNDGQTgrDRQIVPGSKG..GE..EPSPGP
  870-  916 (68.95/45.33)	DLCRRTSGLQHPLPVSQVGSSNIQV..QLHYIEGSYTvlPEvvEASLGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.03|      16|      26|     732|     748|       5
---------------------------------------------------------------------------
  732-  748 (22.46/16.40)	VTVASGsTSGGVPNLTL
  761-  776 (28.57/16.47)	ISINTG.TFPGTPAVRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.94|      19|      26|     987|    1005|       6
---------------------------------------------------------------------------
  987- 1005 (32.64/21.71)	GLRPKKRRMIERDAAFGLN
 1015- 1033 (33.30/22.30)	GIMGSRRDVITTSWKTGLE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28482 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETSLVRSNDGQTGRDRQIVPGSKGGEEPSPGPVRLGNGN
813
851










Molecular Recognition Features






MoRF SequenceStartStop




NANANA