<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28482

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMNPMKESEAEAEAAATVNDPMMEEEEVEAGTVFDISLEQSPSTSLHKITVHESMRSNFSAVAWCAKLNVIACATETCVNGIPRSSVNPWFWIPIHIVIPERPTEIAAFNVVADSSLDSVQSIQWSPICCPRALLIANFQGRVTIWTQPSRGPPNLVIDTNCWQREHEWRQETAVVTKWLSGASPYRWLSSKASAPTDSKSTFVEKFISQQPETSARWPKFLCVCSVSQSGKVQLHWSQRPPTQNATPPKWFCTSKGLIECGPSGIIAADAIITDSGMLHVAGVLAFSPATVIVWVVLPGQGNGLEFSPKTSITTSAPLSPPNWIGFAPLPAFLFSWQDQSIPLHCSTVSNFSAYVSSEAAPSTQCCGVAGVAFDPTRGGSVIAAVVVEGKYMSPHDPDESLSITGWRVQRWESSFQPVVLNPIFGSMDGNPPMRTVWESKVDISIPATDDKSKGIHFNPFDLPKYLGTLARVVFSAQGGEIAVAFFQGRVRIFSGSNFEPVTNYEINVGSSISVPAFSATSCCSASVWHDTSKGEAMLKIIRVLPPPFPIGQEKATSSTWEHAISERFWFSLLVGVDWWDVVGCTQRAAEEGIVSVNGVIAVLDADFHSLPTAQHRQQYCLGLDMIKCRLLVGSNAQEVRATVLDMQARVLLDMLGKGIESALINPSALLPDPWQASEEILSNFDMEEMAVEPELTPCIQAYVDSVIDLASHLITRLRHYAKIFRTLANQAVTVASGSTSGGVPNLTLNPSISGPSSLMLISINTGTFPGTPAVRLIGDCHFLHRLCQLLFFCFFFKRSQLARYKSGLRRTAETSLVRSNDGQTGRDRQIVPGSKGGEEPSPGPVRLGNGNAGQGYSVEEVKVIFQVLLDLCRRTSGLQHPLPVSQVGSSNIQVQLHYIEGSYTVLPEVVEASLGPYMQNMPRLGDADDTGLLLRELQLHPPAEEWHQLNMFVRPCTDSNDTPKPFRSNPLDSRSLESNDIDYGTNGLRPKKRRMIERDAAFGLNTSLGLGAYLGIMGSRRDVITTSWKTGLEGVWYKCIRCMRQTSAFTSLGSANIPHQNERESWWVSRWAYSCPMCGGRWVRVV
Length1086
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.08
Grand average of hydropathy-0.095
Instability index46.29
Isoelectric point5.98
Molecular weight119059.24
Publications
PubMed=22089132
PubMed=24767513

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28482
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.70|      25|      27|     198|     222|       1
---------------------------------------------------------------------------
  170-  187 (23.47/ 9.39)	QETAVVTKWLS..GAS.PYRW.....
  198-  222 (47.00/27.19)	SKSTFVEKFISQQPET.SARWPKFLC
  227-  252 (43.22/24.33)	SQSGKVQLHWSQRPPTqNATPPKWFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     202.23|      58|     110|     306|     373|       2
---------------------------------------------------------------------------
   39-   81 (60.37/32.73)	QSPSTSL..........................................HKI...TVHES...MRSNFSAVAwcakLNVIACATETC.VNGI
   85-  149 (46.40/21.74)	.............SVNPWF.WIPIHIVIPERPTeiaafnvvadssldsvQSIqwsPICCPralLIANFQGRV....TIWTQPS.........
  306-  371 (95.46/77.58)	FSPKTSIttsaplSPPNWIgFAPLPAFLFSWQD................QSI...PLHCS...TVSNFSAYV....SSEAAPSTQCCgVAGV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     195.68|      61|      68|     388|     452|       3
---------------------------------------------------------------------------
  388-  452 (105.61/72.44)	EGKYMSPHD.PDE..SLSITGWRVQRWE...SSFQPVVlnPIFGSMDGNPpmRTVWESKV..DISIPATDDKS
  453-  521 (90.07/50.82)	KGIHFNPFDlPKYlgTLARVVFSAQGGEiavAFFQGRV..RIFSGSNFEP..VTNYEINVgsSISVPAFSATS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.87|      43|      69|     800|     844|       4
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  800-  844 (71.92/54.50)	QLARYKSGLRRTAETSLVRSNDGQTgrDRQIVPGSKG..GE..EPSPGP
  870-  916 (68.95/45.33)	DLCRRTSGLQHPLPVSQVGSSNIQV..QLHYIEGSYTvlPEvvEASLGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.03|      16|      26|     732|     748|       5
---------------------------------------------------------------------------
  732-  748 (22.46/16.40)	VTVASGsTSGGVPNLTL
  761-  776 (28.57/16.47)	ISINTG.TFPGTPAVRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.94|      19|      26|     987|    1005|       6
---------------------------------------------------------------------------
  987- 1005 (32.64/21.71)	GLRPKKRRMIERDAAFGLN
 1015- 1033 (33.30/22.30)	GIMGSRRDVITTSWKTGLE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28482 with Med16 domain of Kingdom Viridiplantae
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