<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28473

Description "Putative coactivator CBP, KIX domain-containing protein"
SequenceMDTNNWRPNQGAEPNMDTSDWRGQLQPESRQRIVNKIMDTLKRHLPVSGQEGLHELRKIAQRFEEKIYTAATSQSDYLRKISLKMLTMETKSQGTISNNIPPNQVGPSNQPPDPGLGIQSQVLNQGQQHPIPLPNQPQSRQQLLSQNIQNNIASQPNLPPVSGLTQTPIANGQNSNIQNMFNASQRQMQGRQQVVPQQQQQQQQQSQNPQQYLYQQQLLRQKLQMQSQQQQQQQHHQQQQQQQQQQQQQQNLLQSNQLQSSQQSVMQQPSMMQTSSLSSIQHNQQSNNGQQSTQSMLQQHPQVIRQQQQQQTSIMHQQQTPITQQSILPQQQQPQQQLMGQQANATNMQHNQILGPQNNVGDLQQSQRLLAQQNNLSNLQQQKLINQQNNLSNINQQLGNNAPGLQPQQVLGPQSGNSGMQTSQHSAHVLQQSKVPMQQQSQQGASNLLPSQPQQSQPQAPQQQLMPQVQSQPAQLQQQPNPLQRDMQQRLQASGSLLQQSGVFDQQKQIYQSQRPLPETSSNSMDSTAQTGQTSGGDWQEEVYQKIKAMKESYLPELSEMYQKIATKLHQHDSLPHQPKSDQLEKLKVFKMMLERLITFLQVSKSNISPSLKEKLGSYEKQIINFINTNRPRKISSLQPGQLPPPHMHSMSQTQPQATQVQSHENQMNTQLQTTNMQGPVPTMQQNNLTSMQHSSLSGVSTAQQNMMNTMQPSASLDLGQGNMSSLQQNSVTAPQQTNVSSLSSQAGVNMIQQNLNPLQPGSGMLQHQQLKQQQEQQMLQSQQFKQQYQRQLMQRQQMIQQQQLHQPAKQQLPAQMQTHQMQQLHQMNDVNDMKMRQGINAKPGVFQQHLASSQRSAYPHQQLKQGPFPVSSPQLLQATSPQISQHSSPQVDQQNHLPSVTKVGTPMQSANSPFIIPTPSPPLAPSPMPGDFEKPISGVSSISNVANVGHQQTGSGAAPAQSLAIGTPGISASPLLAEFTGPDGAHGNALAPSSGKSTVTEEPMDRLIKAVSSLTPAALSAAVSDISSVISMNDRIAGSAPGNGSRAAVGEDLVAMTNCRLQARNFITQDGANGTRRMKRCTNATPLNVVSSAGSVNDSIKLNGMEASDLESTATSNIKKPKFEANHALLEEIREVNQRLIDTVVSISDEEVDQTAAAAAAEGAEGTIVKCSYIAVALSPSLKALYGSAQMSPIHPLRLLVPTNYPNYSPIFLDKFPVESSIENEDLSAKAKSRFSISLRGFSQPMSLKEIAKSWDVCARTVISEYAQQSGGGTFSSKYGSWEDCSTW
Length1289
PositionTail
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.03
Grand average of hydropathy-0.829
Instability index68.58
Isoelectric point9.20
Molecular weight142586.66
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IBA:GO_Central
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28473
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.52|      15|      15|     220|     234|       1
---------------------------------------------------------------------------
  220-  234 (27.60/ 6.22)	RQKLQMQSQQQQQQQ
  236-  250 (27.92/ 6.41)	HQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.36|      27|      31|     863|     890|      10
---------------------------------------------------------------------------
  132-  155 (30.04/ 6.07)	PLP.NQPQSRQ...QLLSQNIQNNI.ASQ
  407-  433 (33.20/ 7.85)	PQQVLGPQSGNSG.MQTSQHSAHVL.QQS
  868-  896 (36.12/12.76)	PFPVSSPQLLQATsPQISQHSSPQVdQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.88|      23|      45|     319|     352|      12
---------------------------------------------------------------------------
  314-  338 (39.74/13.13)	I........M.HQQ..............QTPITQQSILPQQQqpQQQL
  339-  384 (14.14/ 9.50)	MgqqanatnMqHNQilgpqnnvgdlqqsQRLLAQQNNLSNLQ..QQKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     175.25|      47|      56|     921|     972|      13
---------------------------------------------------------------------------
  921-  966 (76.55/35.35)	.......SPPLA....PSPMPGDFEKPISGVSSISNVANVGHQQTGSGAAPAQSL..AI
  967- 1012 (41.46/23.31)	GtpgisaSPLLAeftgPDGAHGNALAPSSGKSTVTE.............EPMDRLikAV
 1013- 1050 (57.23/25.48)	S........SLT....PAALSA.......AVSDISSVISMNDRIAGSAPGNGSRA..AV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     139.07|      31|      31|     482|     512|      15
---------------------------------------------------------------------------
  482-  512 (51.39/23.54)	PLQRDMQQRLQASGSLLQQSGVFDQQKQIYQ
  516-  545 (47.52/21.08)	PLPETSSNSMDSTAQTGQTSGG.DWQEEVYQ
  556-  583 (40.16/16.42)	PELSEMYQKI..ATKLHQHDSLPHQPKS.DQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.55|      10|      19|     798|     807|      17
---------------------------------------------------------------------------
  798-  807 (19.05/ 7.73)	QMIQQQQLHQ
  818-  827 (18.51/ 7.24)	QTHQMQQLHQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.20|      16|      80|     625|     642|      19
---------------------------------------------------------------------------
  625-  642 (27.75/19.80)	NFINTNRPRkiSSLQPGQ
  706-  721 (30.45/15.51)	NMMNTMQPS..ASLDLGQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.36|      19|     112|      46|      67|      23
---------------------------------------------------------------------------
   27-   45 (30.28/20.07)	PESRQRIVN...KIMDTLKRHL
   46-   67 (25.08/25.02)	PVSGQEGLHelrKIAQRFEEKI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28473 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDTNNWRPNQGAEPNMDTSDWRGQLQPESRQRIVNKIMDTLKRHLPVSGQEGLHEL
2) METKSQGTISNNIPPNQVGPSNQPPDPGLGIQSQVLNQGQQHPIPLPNQPQSRQQLLSQNIQNNIASQPNLPPVSGLTQTPIANGQNSNIQNMFNASQRQMQGRQQVVPQQQQQQQQQSQNPQQ
3) QKQIYQSQRPLPETSSNSMDSTAQTGQTSGGDWQEE
4) QMQSQQQQQQQHHQQQQQQQQQQQQQQNLLQSNQLQSSQQSVMQQPSMMQTSSLSSIQHNQQSNNGQQSTQSMLQQHPQVIRQQQQQQTSIMHQQQTPITQQSILPQQQQPQQQLMGQQANATNMQHNQILGPQNNVGDLQQSQRLLAQQNNLSNLQQQKLINQQNNLSNINQQLGNNAPGLQPQQVLGPQSGNSGMQTSQHSAHVLQQSKVPMQQQSQQGASNLLPSQPQQSQPQAPQQQLMPQVQSQPAQLQQQPNPLQRDMQQRLQASGSLLQ
5) QRQQMIQQQQLHQPAKQQLPAQMQTHQMQQLHQMNDVNDMKMRQGINAKPGVFQQHLASSQRSAYPHQQLKQGPFPVSSPQLLQATSPQISQHSSPQVDQQNHLPSVTKVGTPMQSANSPFIIPTPSPPLAPSPMPGDFEKPISGVSSISNVANVGHQQTGSGAAPAQSLAI
6) TNRPRKISSLQPGQLPPPHMHSMSQTQPQATQVQSHENQMNTQLQTTNMQGPVPTMQQNNLTSMQHSSLSGVSTAQQNMMNTMQPSASLDLGQGNMSSLQQNSVTAPQQTNVSSLSSQAGVNMIQQNLNPLQPGSGMLQHQQLKQQQEQQMLQSQQFKQQ
1
88
507
224
795
629
56
211
542
499
966
788










Molecular Recognition Features






MoRF SequenceStartStop




NANANA