<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28466

Description Mediator of RNA polymerase II transcription subunit 36a
SequenceMAPPVRGRGGGGFRGGRGGDRGGRGGGRGGFGGRGGDRGTPFKARGGGRGGGGRGGRGGGRGGGRGGGMKGGSKVIVEPHRHEGIFIAKGKEDALVTKNLVPGEAVYNEKRVTVQNEDGTKTEYRIWNPFRSKLAAAVLGGVDNIWIKPGAKVLYLGAASGTTVSHVSDIVGPTGVVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILGLNASYYLKAGGHFVISIKANCIDSTVPAEAVFSAEVNKLKADQFKPMEQVTLEPFERDHACVVGGYRVPKKKKDAE
Length313
PositionUnknown
OrganismMedicago truncatula (Barrel medic) (Medicago tribuloides)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Trifolieae> Medicago.
Aromaticity0.07
Grand average of hydropathy-0.406
Instability index27.68
Isoelectric point10.08
Molecular weight32947.16
Publications
PubMed=22089132
PubMed=24767513
PubMed=30397259

Function

Annotated function 
GO - Cellular Component
box C/D RNP complex	GO:0031428	IBA:GO_Central
Cajal body	GO:0015030	IBA:GO_Central
small-subunit processome	GO:0032040	IBA:GO_Central

GO - Biological Function
histone-glutamine methyltransferase activity	GO:1990259	IBA:GO_Central
RNA binding	GO:0003723	IBA:GO_Central
rRNA methyltransferase activity	GO:0008649	IBA:GO_Central

GO - Biological Process
box C/D RNA 3'-end processing	GO:0000494	IBA:GO_Central
histone glutamine methylation	GO:1990258	IBA:GO_Central
rRNA methylation	GO:0031167	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28466
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     109.00|      18|      18|       9|      26|       1
---------------------------------------------------------------------------
    6-   22 (37.27/12.74)	.RGR..GGGGFRGGRGGDRG
   23-   39 (41.97/15.32)	GRGG..GRGGF.GGRGGDRG
   44-   59 (29.76/ 8.61)	ARGGgrGGGG.RGGRG...G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.03|      17|      17|     194|     210|       2
---------------------------------------------------------------------------
  174-  197 (20.30/12.52)	TGVVYAVEfshrsgrDLVNMAKKR
  198-  214 (30.72/22.36)	TNVIPIIE.......DARHPAKYR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.62|      13|      17|      65|      77|       3
---------------------------------------------------------------------------
   65-   77 (23.26/10.42)	RGGGM...KGGSKVIV
   81-   96 (17.35/ 6.06)	RHEGIfiaKGKEDALV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     134.83|      40|     159|     101|     141|       4
---------------------------------------------------------------------------
  101-  141 (65.39/44.33)	VPGEAVYNEKRVTVQNEDGTKTEYRIWNPFRSKlAAAVLGG
  263-  302 (69.44/43.01)	VPAEAVFSAEVNKLKADQFKPMEQVTLEPFERD.HACVVGG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28466 with Med36 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MAPPVRGRGGGGFRGGRGGDRGGRGGGRGGFGGRGGDRGTPFKARGGGRGGGGRGGRGGGRGGGRGGGMKGGSKV
1
75










Molecular Recognition Features






MoRF SequenceStartStop




1) MAPPVRGRGGGGFRGGRGGDRGGRGGGRGGFGGRGGDRGTPFKARGGGRGGGGRGGRGGG
1
60