<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28395

Description Uncharacterized protein
SequenceMELLECTNDEPWNRTIFEHLISVMITFMLNSTVRFNEIVVKLNSKLEGRTWTKSSHYVMWFVLNATSGFIGKNMLTDFVPCLRLFDILFPEAEDPDRAIDLPIPCCSRKDSTGQSNDSEISLTQKDGVLPKNILGKELSSTTENTKLSVSQFPISKKMDIDSSDLNRELVTYRDNENEVQEQSSTSAEDSDNECIQNETESLLPPHFRSSTACWKRQGRLLHLATAPVCLWQHVLRKSRLGQDHLPRVMPPALRPIESRISRRMQALVQSVSSTQISNSSVHLVSKLTWNQLFVVLNAFSTDNEVSQLIQRLIDIFWTNETAKDNQKLEHGVLWSRLIKNGKVDFPYDLSAYGRLQPLSHHLMRTMSVHVRMLVLHFFLQKFSVLPNSNMLSTPAIIETFCRILACREVESNNVNRILCLLTKLQPLWSYNTSNTEPKYAVLCGTTEPKVSNYFSCSLVFTLLDTLGFRLADILTPEVRIHTLTSLIGLVKLWSNWSTSVLDNKEPKNLCDGGTSEIPIELQYLLDWNIIKFARSIQAPDCVIYGFCSALTSSTLTQTQPGTNSLHSVNNSACVSQPQSSNIMSQQGSGLVNNTTSGSVSMIRPFIPVNTGVLTSISSSSIIQPPNDPILSSNTGVNSLTGGSGSTGFPNSIPGYPFLMCDNVEVNRFVLYSLLQMYHTFDLEEASGIRPNLVEQIRSMCEQCGPNSLIDLPQLITKRLPDFLILVIRQLTNPNTGELNIGSLPSSDPMNVESMESTLPYTDKSISLSKLCSMVQEEYTSFSNRNFEWSDAVSRSNMFLCLLHHISVRFLNRQLRMLCDYIVSSLTFTAQVNFTTDKCLSTLSDFCIRWHVIPLDRFLLFLANPNNSDSNTQRKSPHSDPLSSRDWFSCIRALHEIIPDQWITYPKTCTISCNTSNDSLEETDKPPHLPVSYGHLLLRLLPLLEVVIMQFLMCEVPFVLLIPFCRAIAPLFRYHRRPVNVCYTVLHDHAEFTMKGLLCKSNIGYPAYHLQLSDTKYLDTSPSSESDMDKTPWIVDRLLCQLLVHCIISKHQRLAMKAALNRSSKGFDQQHSSVNGIFTQQGWNNLLLCVKQSEVFYDVICRNLSNVSSDCNIVHDNTDQSVMNILLNPESFETQFRSMFMTWYSCNIFKYNWEYLFGLIDPICKTNQRHGIYGHSAAWRIWNYEESVCIQTAGLYAASIELMSSFMSPSELTSVVSDLLTNCAKHMYFNQLLNITGALAVILPSVYRFPLFKFCVTLFNDPILCDTTPESNPVDPESMFTCISDVKSTNDHNTNTKWRRSSRALRHRKLLDVNLTSVDNVTLASEATSFKDENSALLKPPKVALYFFEKYLPLDQKTDSDLVDILSNGGCSVIEMSHQNTEASKTLKENFNNLEFSSDVMEYLVKANLWHSIWAHANTSHLASLPGIFSDLILPELRTEAQLLMAFYLVAPLMGSLHSERPAKLVDLTAELYRAVWKVDTVLAKSNYEKSHHSEISIDISNSKQLGEHLPSETGVPLVHVDTIADLLYHIKYMYVGNGVLDQVRPLLPQLRPSLRKRLKFILPQDSSVSQQQQNQNGSHPIFENRVYRASIKPPMCNGDF
Length1600
PositionTail
OrganismSchistosoma mansoni (Blood fluke)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.148
Instability index45.89
Isoelectric point6.17
Molecular weight181091.19
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP28395
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     190.26|      44|      44|     810|     853|       1
---------------------------------------------------------------------------
  770-  807 (50.73/28.36)	.......LCSMVQEEYTSFSNRNFEWSDAVSRSNMFlCLL.HH.ISV
  810-  853 (78.54/48.48)	LNRQLRMLCDYIVSSLTFTAQVNFTTDKCLSTLSDF.CIR.WH.VIP
  854-  898 (61.00/35.79)	LDRFLLFLAN.PNNSDSNTQRKSPHSDP.LSSRDWFsCIRaLHeIIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.27|      27|     712|     539|     581|       2
---------------------------------------------------------------------------
  555-  581 (47.69/48.08)	LTQTQPGTNSLHSVNNSACVSQPQSSN
 1263- 1289 (49.58/19.36)	LCDTTPESNPVDPESMFTCISDVKSTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.62|      10|      15|     206|     215|       3
---------------------------------------------------------------------------
  206-  215 (20.06/10.22)	HFRSSTAC.WK
  222-  232 (15.56/ 6.29)	HLATAPVClWQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.03|      10|     383|      82|      91|       4
---------------------------------------------------------------------------
   82-   91 (19.74/11.90)	LRLFDILFPE
  468-  477 (19.29/11.44)	FRLADILTPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.55|      15|      15|     303|     317|       7
---------------------------------------------------------------------------
  303-  317 (26.70/16.53)	NEVSQLIQRL.IDIFW
  319-  334 (22.85/13.09)	NETAKDNQKLeHGVLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.43|      24|      44|     582|     607|       8
---------------------------------------------------------------------------
  582-  607 (37.10/32.92)	IMSqQGSGlVNNTTSGSVSMIRP.FIP
  629-  653 (40.33/25.48)	ILS.SNTG.VNSLTGGSGSTGFPnSIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.71|       9|      44|     371|     389|      11
---------------------------------------------------------------------------
  360-  368 (17.14/ 9.19)	HHLMRTMSV
  376-  384 (16.57/ 8.56)	HFFLQKFSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.37|      22|      36|     406|     427|      13
---------------------------------------------------------------------------
  406-  427 (38.24/21.89)	CREVESNNVNRILC..LLTKLQPL
  443-  466 (35.13/19.51)	CGTTEPKVSNYFSCslVFTLLDTL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28395 with Med23 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LVTYRDNENEVQEQSSTSAEDSDNECIQNETES
169
201

Molecular Recognition Features

MoRF SequenceStartStop
1) RKRLKFILP
1555
1563