<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28390

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMSERSEMEHAVARVGAGTIPLSILIEFISQKVYTDLMRLIDLLPSKTDLEKKIEIATFFSRTQHLFIRLEALVKWSNSASKVDKCEKISNFLEEQSFFLISTANALSRLLRETLVSARLPPFSVLLAIDIFTNKGYTRLPKSIKNCAFVAESVTEKEKKQALIDLNCIIQNRLSLTQLPHQFRTIKIADGRAEFVVQNEFAVTVTLMSEALDFPWRILDLKFLLKDSSMNYQNLVHPAQTRLIINQAQSRLLYRQFDNRPPLVHLYDMLHAFSLSLQLDMLHEQAQRARSKRPPDQLTIEAYRPSRCLSISYWHGLARTQYNSVMGLDGKLHPTAYLLTIHIDPTEPQRPLCVSHRPELTTSKSQLVGATVQGDCLSIETLLTRTMVARAEQMLQDLRQELLIISPGPVRLADAPLCLYVPLLWPCSPHELLQVRIDPVQGFVCTSFPLLTSLDTEFGAIGSVVVSADFSSSTGVSENFSRSSVINTLSSLESAFNQASCHRVRLVSATGALVQPHESDRICSIQSRSLRNLSHGDARWRSVIRECLEHLRLCLGLARLMQTAKIHRPFWQPFKRHLPLILSPAQVNLSSSWSKMLVRLQQSYRWPILFAQLFPNNEYYIACEVISGPLSVDYKYYLIVCSALPEHMNITTNLQGVLVFNSEINPASGHLNETGLFLQVTHFTSLIADTVWSNNPSTTLEQLCACIKKAQSTIVNQRSTRLNELLNKLKLSHTIDSESVYNDTVVTRKSMRLFEPQATVPTLARLIGTLEENILTNYLTVELSCAGIEHNGMRYDGAGCLSAITITSIPFDPPSWHPSDIIPLVDFVHEMILRPHFDPFTHRRSWQLDIVFTGIVAPLNGINQKSSTYLRHQTAEWTVARLEHFNIVVQNILVEWEKLCLMHALCYHVITNPDVYLPKGAQVYSYNLRTLSLIYGTYYLADISNPTGHKFTLALGFRPTSLNNSSDTTRELNSDDINMSNTINVDFNPHMIARQHLEELLNTRKSIYSLATTMLNTLEFFRCVEPLRDQVLSYNGLKVISPHNHCLQAVCGMLLIALSPNDLILIYRASLSLRITLNIIEHSIVSSTMLSSNNNNDTLKRTKSIQLHDAYNQLTTGKKPYPPIFNTDGWNNQMLDDKALCNLAPLPAFSKFLKSVQELFCINSDEKLTSLTFTQFAQLTILTFDKFKSGIISSKTFSPTNCRRTDPGPTLLESYLSTSLLFHAAILAIQSLDVPIHHVHNEIPYDQQQQTDEQQRIKNQHDLLENAVFICVWPVSQLTVQLSMLCQPTTSNGIESFWWRLKLQLSQSVNSCDRWPPETLNVFEEFFDKRVCSFPFQPSAVTAFFRLLLLPPHALRAMGRVLAFDLHSPAQAPVYVRIGLIGMGVNSRVTAISSSSSLTNQPPNAAASATTGAAQNLLTFDTGSDLQPGMPGIIVRPSKITLQLLITRSHSRHLSKNLIPLAQLVVVGYDWDVNHVVIYPTINQSQNIITNNRNQSDTINLNLLRLLHDTDVESKANAMATNSNDSALVQLVLLITQTVAASYPISSSDSTSLNNSNVMTGFGIGGGGGGNVNSGAGIGSQQVLYG
Length1585
PositionTail
OrganismSchistosoma mansoni (Blood fluke)
KingdomMetazoa
Lineage
Aromaticity0.08
Grand average of hydropathy-0.043
Instability index43.89
Isoelectric point7.73
Molecular weight177684.03
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28390
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.72|      22|      32|    1287|    1316|       1
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  583-  603 (35.92/14.51)	PAQVN.LSSSWSKMLVRLQQSY
 1287- 1308 (40.86/18.39)	PTTSNGIESFWWRLKLQLSQSV
 1318- 1326 ( 1.94/10.01)	..TLNVFEEFF...........
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.55|      23|      32|    1481|    1503|       2
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 1481- 1503 (38.11/21.87)	INQSQNIITNNRNQSDTINLNLL
 1511- 1533 (35.44/19.84)	VESKANAMATNSNDSALVQLVLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.69|      12|      32|     712|     723|       3
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  712-  723 (20.94/11.09)	TIVNQRSTRLNE
  743-  754 (19.75/10.05)	TVVTRKSMRLFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.54|      29|      32|     951|     982|       4
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  954-  982 (49.08/28.79)	LGFRP.....TSLNNSSDTTRELNSDDINMSNTI
  984- 1017 (42.46/17.92)	VDFNPhmiarQHLEELLNTRKSIYSLATTMLNTL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     190.06|      58|     579|     506|     573|       5
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  234-  294 (88.59/48.69)	LVHPAQTRLIINqAQSRLLyRQF...DNRPPLVhLYDMLHAFSLSLQLDMLHEQAQRARSKRPP
  512-  572 (101.46/67.46)	LVQPHESDRICS.IQSRSL.RNLshgDARWRSV.IRECLEHLRLCLGLARLMQTAKIHRPFWQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.06|      30|      32|      30|      59|       7
---------------------------------------------------------------------------
   30-   59 (48.24/34.74)	QKVYTDLMRLIDLLPSKTDLEKKIEIATFF
   63-   92 (49.82/36.14)	QHLFIRLEALVKWSNSASKVDKCEKISNFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.18|      16|      63|     337|     352|       8
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  337-  352 (31.73/19.21)	LLTIHIDPTE.PQRPLC
  401-  417 (24.49/13.01)	LLIISPGPVRlADAPLC
  431-  444 (25.97/14.27)	LLQVRIDPV...QGFVC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.16|      21|      32|    1329|    1349|      10
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 1329- 1349 (37.23/23.73)	RVCSFPFQ.PSAVTAFFRLLLL
 1359- 1380 (31.93/19.21)	RVLAFDLHsPAQAPVYVRIGLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.00|      23|      34|     832|     854|      12
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  832-  854 (45.62/33.68)	LRPHFDPFTHRRSWQLDIVFTGI
  869-  891 (39.37/27.82)	LRHQTAEWTVARLEHFNIVVQNI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.32|      30|     715|     450|     480|      13
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  450-  480 (45.38/35.81)	LTSLD.TEFGAIgSVVVSADFSSSTGVSENFS
 1167- 1197 (44.94/29.91)	LTSLTfTQFAQL.TILTFDKFKSGIISSKTFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.68|      15|     300|     629|     646|      14
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  617-  631 (26.72/17.28)	EYY.IACEVISGPLSV
  634-  649 (23.95/12.45)	KYYlIVCSALPEHMNI
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---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.84|      18|      31|     898|     919|      15
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  898-  919 (31.24/28.01)	LCLMHALCYHvitnPDVYLPKG
  930-  947 (32.59/19.09)	LSLIYGTYYL....ADISNPTG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28390 with Med14 domain of Kingdom Metazoa
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