<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28379

Description Uncharacterized protein
SequenceMHDIAKCSDNLKFLDLLATVRADQIHLGSNNTRTGPYLIRYSTFLNHLQRIAIHCGLQLSSGPCSGGGTSAGALVWRLTSECFAVVVAATNNSITTSDPTYNNSPELTDLISIAAVYFEFNHDKAVPCPELATDLSMGKYSSLLQHVDNLLTIYAVPGDKIDRARTYLCLQALEKDLSMLTQAMRTDLENNIDAISTFRRAPNQKHDVFSMRNLVNRSLVGHFVGRTGGRLARLTYLVTSAQAMISNATGVMKNNLQMNSKSTYSTSIGCGSRDGLIGGYMARIGLCPRLSYVEDTSVVVQSAVQRLPFMPLVTLQKDAYGISVPHFAQPDEIKCISIEAEFVLHLDPPLPISTDAIQQLERTTGLSNTEIIDQKEEDIVLLILRKHKQEHLYGINTHLQNPNITQHSYQIKSDVKAYLVSSVPFTCSDQIGEIISILRKQASALAFYETFIVHPDKPVEKDDSLTFSFDIKIMGSQMISLEFDDPNRVGAKIHASLHVRPFDVQCLELNYFPNAHDRLNSNCPSNDKEVDVMPLTKLDIESGGNLKANFSKILTKTHTLPIGFVWLLTQLQCPVHKQLVSMKLPVTNSYNSTENKESCSSVNQKQLTSLRTMLNRVKSSIIIRGANGTGGVLCGGDRKVSLDFESSSSFAAAQVFALNTPSYLNSAKKIPPLPPGVMATPPPAFTHLDTSSSDFGIISSLRPVNSQGKLRDMHSSSSLPVVSTNPSRGLRLDDLLVDSTFQTQQQLQQHNQQRNAPPISFSHSLPSYVSPIPGTHTASLSDVKEAYSDMINPNISTSNHLSLPTIHSSHKYGSSVLSGSNSIPSNFYNMPSMSISASGSEATSSSAVTKSKSFTASPVSDNSRAPSTSGSMLVNLLNEDSLSTSIPLVSPSSMTDRHHYNTSHSLTNLQNSPLTSAAGIINVSNSRLPGMMLSNNSQPPSSDAPNLTPNSSQYPSVRNSSLITPNTGRTKHASLKNSQTSVTVNPTSNPKKPRKRRRGTVEGSFRCISSQKGNTPVPSVYSNYPTTKHQRVDTVLPTTSISLSGAYQRPTFNQANSNFSSSSLPYVQQSTVASTVQSISMQTPNPSKSVYDFDDNPGSMFDVPVGNISSSNSLSFSSGSSLTSPKSGVSVNLLQSGSLAVTNTNPVSNFPVTTMISSNSNLERAIERITSMYLTNYHVRSFGSSTPKARVNFSQNEVDNYNKIQSVQSNSTPINTSDSGGTVPPTQSLSSVKKRKKRSVEGKPSAYMLQMLQLANSSISGSDASITTTSVTTGASGVPNQSAITPLVLNNSGLKQIKSTNKLVGHGSVLVKKERKRRLGHGFTEKTHFSFIPNSNTYNQVQETADTSNIPKLMKINRVSRPPSSDVPKDNQTGSGTTPNLYSNCISMSPNSSSKKKVSALNSNPLGTGVGIGSGSDDMIVSKRLFSTSTSPLVSGDKRKRNPETSKQSNNSQSAYSNSGTSSDPAFIPSPLLPPTSSDPPTNSNTSRKTPCPSLHTAPNLPRVSHIPTSKSQPVQQSNTLNYISSSSVCTANPASVSVVSSSSGLIKGYKIPKKKSTTTGCLPSIPLSDASGDKSVGMLSTTLQQIQESISSYRDTPDSQSPEKSDESSLAIVENLYPSSNDPNLEGVDTINVAVYSANVNGVANNTDDNSLFPSDSVSGYTAPNTENFSQSILHPISLQSNSSVSVQCSQSSQQQQQFPRKSSVKSISDIVDKLRAKSTTSISSSTSTIISDSSNIGSSDTTAITSYEVKDSTINPMLSDNPSCVRSITKKNDEFQDQWRDNIFEKFCPSGTPTPHQSENGQNNICRSDSEVDLSTSIENNEESVWTSGNKEPVYDKDERNISSSNSGAPMIHSNTQSISDSERKQGKQQFECIKANTDTPASPTELLTTVPTSNSNVSSKIIPISPTSMKCLNSTGSVSGTNMKPNIVRHSSLRFEKKTGSGRYSRLGGGVNGMMLHGGLVQRSNSDNYSHSSGVHGHSNRLPRGGMNNPVNSVFITISFVKSSSILRVCYNLHFE
Length2019
PositionMiddle
OrganismSchistosoma mansoni (Blood fluke)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-0.437
Instability index47.11
Isoelectric point9.00
Molecular weight217747.76
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28379
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     478.01|      67|      70|    1432|    1498|       1
---------------------------------------------------------------------------
  793-  858 (41.43/ 8.01)	PNIST.S.....NHLSLP..TIHS.....SHKYGSS...............VL.SGSNSIPSnFynmpsmsI....S.ASGS......EATSSSAVTKSKSFTASP..............
  913-  978 (57.20/14.04)	PLTSA.AgiinvSNSRLP.GMMLS.....NNSQPPS...............SD.A.....PN.L.......T....PnSSQY......PSVRNSSLITPNTGR.TK.....HASL..KNS
 1318- 1389 (55.44/13.36)	RLGHG.F.....TEKTHFSFIPNS.....NTYNQVQ...............ET.ADTSNIPK.L.......M....K.....inrvsrPPSSDVPKDNQTGSGTTPnlysnCISM....S
 1432- 1498 (116.81/36.81)	PLVSG.D.....KRKRNPETSKQS.....NNSQSAY...............SN.SGTSSDPA.F.......I....P.SPLL......PPTSSDPPTNSNTSRKTP.....CPSL..HTA
 1502- 1571 (61.12/15.54)	PRVSHiP.....TSKSQP..VQQS.....NTLNYIS...............SS.SVCTANPA.S.......VsvvsS.SSGL......IKGYKIPKKKSTTTGCLP.....SIPL..SDA
 1598- 1664 (42.08/ 8.26)	P.....D.......SQSPEKSDES.......SLAIV...............ENlYPSSNDPN.L..egvdtI....N.VAVY......SANVNGVANNTDDNSLFP.....SDSVsgYTA
 1758- 1819 (60.35/15.24)	PMLS..D.....NPSCVRSITKKN.....DEFQDQW...............RD.NIFEK....F.......C....P.SGTP......TPHQSENGQN.NICRSDS.....EVDL..STS
 1835- 1911 (43.58/ 8.83)	PVY...D.....KDERNISSSNSGapmihSNTQSISdserkqgkqqfecikAN.TDT...PA.........S....P.TELL.........TTVPTSNSNVSSKII.....PISP..TS.
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     115.47|      27|      46|    1087|    1113|       4
---------------------------------------------------------------------------
 1087- 1113 (48.72/31.58)	SKSVYDFDDNPGSMF..DVPVGNISSSNS
 1136- 1160 (42.58/26.40)	SGSLAVTNTNPVSNF....PVTTMISSNS
 1163- 1185 (24.17/10.88)	ERAI....ERITSMYltNYHVRSFGSS..
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     172.88|      50|     797|      61|     110|       5
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   61-  110 (87.44/47.08)	SGPCSGGGTSAGALVWRLTSECFAVVVAATNNSITTSDPTYNNSPELTDL
  860-  909 (85.43/45.81)	SDNSRAPSTSGSMLVNLLNEDSLSTSIPLVSPSSMTDRHHYNTSHSLTNL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     243.76|      71|     627|     585|     678|       6
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  585-  671 (108.38/83.15)	PVTNSYNSTENKESCSSVNQKQLTSLRTMLNRVKSSIiirganGTG.GVLCGGDRKVSLD..FESSSSfaaaqvfalnTPSYLNSAKKIP
 1224- 1279 (94.00/46.88)	PPTQSLSSVKKRKK.RSVEGKPSAYMLQMLQLANSSI.............SGSDASIT....................TTSVTTGASGVP
 1391- 1431 (41.38/13.45)	......NS.SSKKKVSALNSNP.......L.............GTGvGIGSGSDDMIVSKrlFSTSTS......................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.00|      23|     628|    1058|    1080|       8
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 1058- 1080 (39.97/19.34)	NFSSSSL.PYVQQSTVA..................STVQSIS
 1669- 1710 (23.47/ 7.74)	NFSQSILhPISLQSNSSvsvqcsqssqqqqqfprkSSVKSIS
 1723- 1740 (22.56/ 7.09)	SISSSTS.TIISDS.....................SNIGS..
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.97|      17|     261|     426|     443|      10
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  426-  443 (26.41/21.11)	TCSDQIGeIISILRKQAS
  690-  706 (30.55/19.40)	TSSSDFG.IISSLRPVNS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.80|      26|     617|    1289|    1314|      16
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 1289- 1314 (42.52/27.13)	LNNSGLKQIKSTN...KLVGHGSVLVKKE
 1915- 1941 (34.32/20.11)	LNSTG..SVSGTNmkpNIVRHSSLRFEKK
 1959- 1976 (24.96/12.10)	L.HGGLVQ.RSNS...DNYSHSS......
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28379 with Med1 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) DNYNKIQSVQSNSTPINTSDSGGTVPPTQSLSSVKKRKKRSVEGK
2) DSTFQTQQQLQQHNQQRNAPPISFSHSLPS
3) IQESISSYRDTPDSQSPEKSDESSLAIVENLYPS
4) MLHGGLVQRSNSDNYSHSSGVHGHSNRLPRGG
5) NIFEKFCPSGTPTPHQSENGQNNICRSDSEVDLSTSIENNEESVWTSGNKEPVYDKDERNISSSNSGAPMIHSNTQSISDSERKQGKQQFECIKANTDTPASPTELLTTVPTSNSNVSSKIIPI
6) QVQETADTSNIPKLMKINRVSRPPSSDVPKDNQTGSGTTPNLYSNCISMS
7) SGSEATSSSAVTKSKSFTASPVSDNSRAPSTSGSMLVNL
8) SSSKKKVSALNSNPLGTGVGIGSGSDDMIVSKRLFSTSTSPLVSGDKRKRNPETSKQSNNSQSAYSNSGTSSDPAFIPSPLLPPTSSDPPTNSNTSRKTPCPSLHTAPNLPRVSHIPTSKSQPVQQSNTLNYISS
9) TSIPLVSPSSMTDRHHYNTSHSLTNLQNSPLTSAAGIINVSNSRLPGMMLSNNSQPPSSDAPNLTPNSSQYPSVRNSSLITPNTGRTKHASLKNSQTSVTVNPTSNPKKPRKRRRGTVEGSFRCISSQK
1199
738
1587
1958
1784
1340
838
1392
884
1243
767
1620
1989
1907
1389
876
1526
1012

Molecular Recognition Features

MoRF SequenceStartStop
1) LIKGYKIPKKK
1546
1556