<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28363

Description Serine/threonine-protein kinase prk1
SequenceMMYGTNRARNQKAETSYRGYQRSNAGPLNYQTKVRITDRYKVIGFISSGTYGRVYKATGRQGQTGEFAIKKFKPDKEGEAVVNYTGISQSAVREMALCSELRNHANVIRLIEIILEDKCIFMVFEYAEHDLLQIIHHHTQTPRHPIAPGTIKSIMYQLLQGVQYLHTNWVLHRDLKPANIMVTSSGEVKIGDLGLARVFKQPIHNLYMGDKVVVTIWYRAPELLLGSKHYTTAIDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQKHQMQKIVDVMGLPTRERWPLLASMPEYSQLSTLQPPLLSTNTSHSHGGHHPYGHRSQQQPPASQNTHGNLQKWYHQTTVSTPLTSLGAEGYKLLASLLEYDPEKRLTAADALVHPFFTSPTSTPLASLNSNTANSTSQGTGAAAVNWSPTNCFEGLKNETYPCRRVSQDDNDIGFGTGTGNQSGSRVNTAAAGTGTGLVMGQAQSQVQAMGGSLGNIGGHGHGHGHGQMGGGGMGQGMGGLGQGHGGMAQMAGMKRMHDAAAAAAAAAAAAATQQSHPNKRMKGSQG
Length557
PositionKinase
OrganismNeurospora tetrasperma (strain FGSC 2509 / P0656)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Sordariales> Sordariaceae> Neurospora.
Aromaticity0.07
Grand average of hydropathy-0.425
Instability index34.19
Isoelectric point9.44
Molecular weight60414.80
Publications
PubMed=21750257

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28363
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.48|      16|      16|     467|     482|       1
---------------------------------------------------------------------------
  467-  482 (28.45/11.55)	GLVMGQAQSQVQA.MGG
  485-  501 (28.04/11.28)	GNIGGHGHGHGHGqMGG
  509-  523 (27.99/11.24)	G.GLGQGHGGMAQ.MAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.22|      16|      23|     295|     311|       2
---------------------------------------------------------------------------
  290-  306 (25.18/14.29)	LLASM.........PeYSQLSTLQPP
  307-  331 (24.04/ 9.72)	LLSTNtshshgghhP.YGHRSQQQPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.34|      12|      16|     198|     211|       3
---------------------------------------------------------------------------
  198-  211 (18.10/18.04)	V.FKQPihNLYMGDK
  216-  228 (16.24/ 8.11)	IwYRAP..ELLLGSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.61|      11|      19|     435|     449|       4
---------------------------------------------------------------------------
  435-  449 (16.32/20.95)	RVsqddNDIGFGTGT
  456-  466 (20.29/12.04)	RV....NTAAAGTGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.17|      12|      16|     393|     404|      12
---------------------------------------------------------------------------
  393-  404 (20.01/13.47)	TPLASLNSNTAN
  410-  421 (22.16/15.70)	TGAAAVNWSPTN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28363 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) CRRVSQDDNDIGFGTGTGNQSGSRVNTAAAGTGTGLVMGQAQSQVQAMGGSLGNIGGHGHGHGHGQMGGGGMGQGMGGLGQGHGGMAQMAGMKRMHDA
2) LQPPLLSTNTSHSHGGHHPYGHRSQQQPPASQNTHGNLQKWYH
3) SPTSTPLASLNSNTANSTSQGTGAAAVNWSP
433
303
389
530
345
419










Molecular Recognition Features






MoRF SequenceStartStop




1) AAAAAA
2) QSHPNKRMK
534
545
539
553