<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28351
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MQPTHIERAFSQVPPLNTQALGQMAGPNDLAYDAHSPQSTGSPEPPSGVLTDAEAKLWELVIAIHGVQTRFNRPVVVNGSGPNANANSGINGINGSAGGAGAGFGGVNGMASGNQLNLAEPIQAIVQKMMEVDDIAARVPTMIPRQAVEDLDNTHHPGHVLKERIEAVSLENAFLNGKIAAISSFRDLLGDALADAFPELSGLRSHPPAGANRATSVPATAPHNSSTPVMIKQEEH |
Length | 236 |
Position | Middle |
Organism | Serendipita indica (strain DSM 11827) (Root endophyte fungus) (Piriformospora indica) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes>
Sebacinales> Serendipitaceae> Serendipita.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.233 |
Instability index | 41.47 |
Isoelectric point | 5.38 |
Molecular weight | 24558.20 |
Publications | PubMed=22022265
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP28351
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 114.86| 37| 161| 6| 48| 1
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6- 48 (59.23/48.64) IERAFsqvppLNTQaLGQMAGPNDLAYDAHS...PQSTG.SPEPPSG
170- 210 (55.63/31.09) LENAF.....LNGK.IAAISSFRDLLGDALAdafPELSGlRSHPPAG
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|