<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28348

Description Uncharacterized protein
SequenceMGPSAPKTGQEPSKPYEAKPPEWVTGATRDGDLGYHGYFPPRPGQDEDILSDNNILYGYTEPQFVTGELWQGTDTFRGVFKENGKNGLESLQEIMEKVMARRAELHAGVDANSFKLPSRVTLTGDKRTAWFKDLADPNVSLQKIAKSAVITSKSQETLEMLYVNNTPPDRTVWYIRALAVIEVYGRNKTSTQPSTATDWTNVITGYLKKQLVEIGITTVRTGSNIKQSFRKSKLSEADSRENWVSRFAFSLDILRLLFDGDLLDQPTFLGWIAAMASPSEGLGPHQFVFLSRIIDEYFDVVASNRAFATPVVEGCLAQWAEIEPSPLRQHGAFVLNEIARLVLRFLCVDTDCFLSRHILSNHSAALSAMVGHALQLLDPDSRLAMQDISMRRLKLLTERGNAILQMQIPPDEEAQDVEICLEDISTLNTIDTTTNLIELSFLPIPTQTPTGGFDFKLFSRRLSTLLSWSIHPDQSGDSEIRPYLASALILLWRQSVATVVPNVGQTLQRHLLTWLEGRGLVRPLAEIADSSLGDSPEEVEKMNATLTLFGELVHRRLFSFSDYLTRMASFGQISSSPPRGVSSSPAAMTTPGACTANALSRHLELLRCIPLWDKVSEQVLNQRKIVLYGIRARKTADDATEKEIRAEIRRVLPIFFNGPPTEIPFSMDQLPTSLSASKFVRVRVLHHWLFDLVKDYIARVSPMADVQQAPLLSLPIYTTLVQIFINTGCYRTVWELNQALLLHVTDRELLVAILSCLRCYLDLWVGMLLVDKISNALLDAHARLKEQVRQPPRRLLLLLSELKSSCVLSEPVKGRIDFELEQFEESQKLLFTDSSSSSPAPPLLPPIKAVIEENSLAKPVDLASILWHKNKTHADWGLAAWQATIMAICTCKWDPSLTDAEMADRFATFVWHIDAHLPHGIGDTVATWFETTGATSLLSITDNCWDIIKIMCYKMLLDYIVTPKTVLSGLIYPAVKAAVANQLEHPSDTMAPYLQRALDLFNLVTRCDSPVMNLYSEQSPIFMLDALCCRARCLHASNTGALLDVLSDLTLIEVMSSDGSDQRMRLEQLRYGVQSDPYLKAQLLSRADLVYNAFERNLRGHQAYSSRLIVRLRSLLDSRVSSAITPENATIETWATALNAVSVWTFPTLSVDIRLLRALVNDPKPNIQDNPSVTEIDRDRIRENLATALLDQKLSPAETALLQALLKDAIPALCCKIVTHGFKRLASLLEVPHEGGSLEQLLAFSRPLNQTLRLMLTFGRLRGPISPTQDLTSLQDTFLSSWMARTLRLRSTINSEERKLGGRDVHKVLDAICLMLRALHFFDEVAGPDLGPKTMELVTELMELAITVGGAAVYDEMTFNITVDTLCILYDDCKKETRPQILRALNERFSLTSLPPQLPAQSRIRLGRLVPFVPRDKYGANLAFAQRVDGVLELKSQARGRPWEWTDNIDPVEPPGILNTRIKNTSAVPLELFEVASKGESILPESFAHEVTGKSGDIWSFRDTLASEGLMSRAWRESRGAWDARSLDGTGSDRDRVAGSGGAGGGTSSSMRGHSPAAASSSAHLSTSSRMASPSVAMNPMAVPPSRMQPLSMPTVETIIAEPVVESSNEAGRGLKRKARLDEEEGEDDDIIMLTERPAVGGKTTQKKPKAKTKSKK
Length1657
PositionKinase
OrganismSerendipita indica (strain DSM 11827) (Root endophyte fungus) (Piriformospora indica)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Sebacinales> Serendipitaceae> Serendipita.
Aromaticity0.07
Grand average of hydropathy-0.144
Instability index45.37
Isoelectric point6.05
Molecular weight184078.00
Publications
PubMed=22022265

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28348
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     648.16|     244|     398|     350|     618|       1
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  272-  445 (237.68/141.63)	...............................................................................IAAMASPSEGLGPHQFVFLSRIIDEYFDVVaSNRAFATPVVEGCLAQWAEIEP..SPLR..........QHGAFVLNEIARLVLRFLCVD......................................................................................................................................TDCFLSRHILSNHSAALSAMVGHAL......QLLDPDSRLAMQ..DISMRRLKLLTE.RGNAILQmqiPPDEEAQDVEI.CLEDISTLNTIDTTTNLIELSFLPiP
  449-  610 (200.11/135.97)	PTGGFDFKLFsRRLSTLLSWSIHPDQS....GDSEIRPYLASALIllwRQSVATVVPNVGQTLQRHLLTWLEGRGLVRPLAEIADSSLGDSPEEVEKMNATLTLFGELV.HRRLFSFSDYLTRMASFGQISS..SPPRGVSSspaamtTPGACTANALSRHLELLRCIP................................................................................................................................................................................................................................................
  745-  846 (74.30/28.02)	.........................................................................................................................................................................lwdkvseqvlnqrkivlygirarktaddatekeiraeirrvlpiffngppteipfsmdqlptslsaskfvrvrvlhhwlfdlvkdyiarvspmadvqqapllslpiyttlvqifintgcyrtvwelnqalllhvTDRELLVAILSCLRCYLDLWVGMLLvdkisnALLDAHARLKEQvrQPPRRLLLLLSElKSSCVLS...EPVKGRIDFELeQFEESQKLLFTDSSSSSPAPPLLP.P
 1147- 1273 (136.07/66.08)	PTLSVDIRLL.RALVNDPKPNIQDNPSvteiDRDRIRENLATALL...DQKLSPAETALLQALLKDAIPALCCKIVTHGFKRLA..SLLEVPHEGGSLEQLLAF......SRPL...NQTLRLMLTFGRLRGpiSPTQDLTS...........................................................................................................................................................................................................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     338.57|     116|     795|      69|     204|       3
---------------------------------------------------------------------------
   69-  204 (161.93/158.67)	LWQGTdtfrgvfKENGKNGLESLQEIMEKV.............MARR.AELHAGVDANsfkLPSRVtltGDKRTAWFKDLADPnvSLQKIAKSA..VITSKSQETLeMLYVnNTPpdRTVW....Y..IRAlAVIEVYGRNKTSTQP..STATDWTNVIT
  866- 1005 (176.64/114.84)	LWHKN.......KTHADWGLAAWQATIMAIctckwdpsltdaeMADRfATFVWHIDAH...LPHGI...GDTVATWFETTGAT..SLLSITDNCwdIIKIMCYKML.LDYI.VTP..KTVLsgliYpaVKA.AVANQLEHPSDTMAPylQRALDLFNLVT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     190.31|      60|      64|    1316|    1379|       5
---------------------------------------------------------------------------
 1316- 1379 (93.47/81.42)	LRALH.FFDEVAGPDLGPKTMELvtELMELAITVGGAAVYDEMTFNITVDTlcILYDDCKKETRP
 1382- 1442 (96.84/69.89)	LRALNeRFSLTSLPPQLPAQSRI..RLGRLVPFVPRDKYGANLAFAQRVDG..VLELKSQARGRP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28348 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AWDARSLDGTGSDRDRVAGSGGAGGGTSSSMRGHSPAAASSSAHLSTSSRMASPSVAMNPMAVPPSRMQPLSMPTVETIIAEPVVESSNEAGRGLKRKARLDEEEGEDDDIIMLTERPAVGGKTTQKKPKAKTKSKK
1521
1657










Molecular Recognition Features






MoRF SequenceStartStop




1) DLGYHGYFPPRP
2) QEPSKPYEAKPPEWVTGATR
3) RGLKRKARLDEEEGEDDDIIMLTERPAVGGKTTQKKPKAKTKSKK
32
10
1613
43
29
1657