<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28341

Description "Related to SSN8-DNA-directed RNA polymerase II holoenzyme and SRB subcomplex subunit, cyclin C homolog"
SequenceMATDYWASSHNKKWVVDRLALFTSRAEDLRFTTPEHLAFLHIFFANLIFKIGKRLHFRQRVIATATVFFRRFYLKNHLCDTEPYIVLVACCYLAGKAEELPAHIKNVINIANTVFGELGVWPAPLDNHRLAEMEFYLVDELECDLTVFHPYRSLLALCGKETDEAGMGGPGHTGQETAPDLGVGVISGERYWGTGAGKLLLDDRTLQLAWLIINDTYRTDVCLLYPPFLIAIAAIYLSLVNHDRISKAHGSPDDPQTQDASDQLQISASTPMVTSPSLVASTPKAPTAPLGPDPITFLANLNVSMATVAAIAQEMLSFYTLSARYVDDSGNGGANAAQRQRSTDNDVQMSDGTSESTIGEKVRARQLVEVLRRMRTEKERESEGASINSVGPLMSPTATVGVQGKTGGAGRGVQEYHAVAQWRWKIEGRDETGDEDDEDEVCGICRIAYDGCCPDCKFPGDDCPLVCGKCTHVFHMHCIEKWIATPSSNRQCPMDRRVWVNAGEADPVEPEQPAQEPSMDA
Length521
PositionKinase
OrganismSerendipita indica (strain DSM 11827) (Root endophyte fungus) (Piriformospora indica)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Sebacinales> Serendipitaceae> Serendipita.
Aromaticity0.08
Grand average of hydropathy-0.238
Instability index42.23
Isoelectric point5.16
Molecular weight57427.37
Publications
PubMed=22022265

Function

Annotated function 
GO - Cellular Component
anaphase-promoting complex	GO:0005680	IEA:InterPro
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cullin family protein binding	GO:0097602	IEA:InterPro
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
DNA-directed 5'-3' RNA polymerase activity	GO:0003899	IEA:UniProtKB-KW
ubiquitin protein ligase activity	GO:0061630	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
anaphase-promoting complex-dependent catabolic process	GO:0031145	IEA:InterPro
cell division	GO:0051301	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28341
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.49|      20|     360|      90|     144|       1
---------------------------------------------------------------------------
   61-   80 (39.28/36.10)	VIATA.TVF................FRRFYLKNHL.CD
  107-  144 (19.22/34.89)	VINIAnTVFgelgvwpapldnhrlaEMEFYLVDELeCD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.31|      31|      36|     238|     270|       2
---------------------------------------------------------------------------
  238-  270 (48.02/32.97)	SLVnhDRISKAHGSPDDPQTQDASDQLQISAST
  277-  307 (53.29/30.24)	SLV..ASTPKAPTAPLGPDPITFLANLNVSMAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.79|      18|      24|     436|     453|       4
---------------------------------------------------------------------------
  436-  453 (37.61/25.33)	DDEDEVCGICRIAYDGCC
  461-  478 (40.19/27.58)	DDCPLVCGKCTHVFHMHC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28341 with CycC domain of Kingdom Fungi
Unable to open file!