<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28332

Description "CMGC/CDK/CDK8 protein kinase, variant"
SequenceMRPFQRREYPLDRGLGPPAYQSKVRVMDKYQVIGFISSGTYGRVYKARGRQGQPGEFAIKKFKPDKEGEQITYTGISQSAIREMALCSELRHPNVIRLVETILEDKAIFMVFEYAEHDLLQIIHHHTQQPKHPIPPQTIKSIMFQLLNGCQYLHTNWVLHRDLKPANIMVTSSGEVKVGDLGLARIFWKPVRTLMQGDKVVVTIWYRAPELLMGSHHYTPAVDMWAVGCIFAELLSLRPIFKGEEAKMDNTKKGGSRDMPFQRHQMQKIVDIMGMPTKERWPLLTSMPDYDKLPLLQPPLSASGYSQQPAHSHHHHQHYNQGPQYGGRAGGPTSSSSANSSSAAAAASQSHLDKWYYHTVSQGQTAGPMPHAPPGSLASLGVEGYKLLAGLLEYDPEKRLTAAAALQHNFFSTGDRVSANCFEGCKAEYPHRRVSQEDNDIRTGSVPGTKRSGMPDDSMGRPGKRVKE
Length468
PositionKinase
OrganismMagnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Magnaporthales> Pyriculariaceae> Pyricularia.
Aromaticity0.08
Grand average of hydropathy-0.546
Instability index41.49
Isoelectric point9.29
Molecular weight52407.26
Publications
PubMed=15846337

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28332
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.51|      11|      15|     186|     197|       1
---------------------------------------------------------------------------
  186-  197 (17.23/12.95)	IFWKPVRTLMqG
  204-  214 (20.29/10.47)	IWYRAPELLM.G
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.43|      26|     188|     249|     278|       2
---------------------------------------------------------------------------
  249-  278 (42.35/34.51)	DNTKKGGSrdMP.FQRHQMQKivDIMGMPTK
  438-  464 (46.08/25.53)	DNDIRTGS..VPgTKRSGMPD..DSMGRPGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.90|      28|      35|     311|     340|       3
---------------------------------------------------------------------------
  311-  340 (49.34/33.56)	HSHHHHQHYNQGPQygGRAGGPTSSSSANS
  349-  376 (55.56/31.20)	QSHLDKWYYHTVSQ..GQTAGPMPHAPPGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.91|      11|      37|     383|     399|       4
---------------------------------------------------------------------------
  383-  399 (11.90/20.16)	EGYKllaglLEYdPEKR
  423-  433 (24.01/13.17)	EGCK.....AEY.PHRR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28332 with CDK8 domain of Kingdom Fungi

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