<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28316
Description |
Mediator of RNA polymerase II transcription subunit 16 (Fragment) |
Sequence | MPLMMDDSINVDDLFGEPTSLELGLPPSASPARGLAQRLDEMRLLGCCQKIAWSKLGCIAYISQDSLRVKVRHLQCRPSDGKWVLSDETPLMPITEAHGGHALTHLSWNEAGSDLAVVDVTGRVSVYHIPFALNSVNGLRQPAFSPDDGSQIVGMMWLNTQRSLLYQNPDGRWDDISVDLKSTSYSDRLLSHAALVATQNGILVATYSVCQKIRFYRVQINWNPPQWDPAQQPKQTPPQFPVPSFRFTHSKVETSCTVPGMHRNDGEEPDMMHQSISNPLYTLSRLDIILPASDNAAGTTANPWIVAVFSTPPQATPDHPGPQGPASVIVRWQLDTAAFTLHPKFDEMAAKRNSTQIKPRPVLRRLEDIYSDRYVISVDQIEYGNVVAITYDDSSVSFYDPKTMALFNGVDDANTVTGLAQAGFHYAPDASGQGQHVSFSPSACAAVMLDSDGQTHLRVMEHSYGAENGLYDENKFSAAIASLTLAFCRGCGSEVNTDDILLILIQQLSQDAQITFINEVYRALPINCNFTVEQEKLMNHPYIPKCLSIQAALGFADKYKPRSFASSVSWSILQLRHAAILYPFFFQYNKGIQAEPHDPGYVSADQEAFSQKLKTTNSLALIILLSSMSRAFLRFICRGLRGIHAGYTNASLGGDSRLQYAEICQALDATPARIDVYEKFLSAVDSAVRHAYHGAGFGDTERPGPEKELLVNARIPPVLVAAVSTILRQTVPGLKSEVDRMAIYMHDYSWLGFGSDLRSELYRRTREVDIIKKTPIRMTIAQGS |
Length | 784 |
Position | Tail |
Organism | Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus>
Aspergillus subgen. Circumdati.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.197 |
Instability index | 42.41 |
Isoelectric point | 5.94 |
Molecular weight | 86723.42 |
Publications | PubMed=21543515
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP28316
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 293.32| 76| 87| 72| 157| 1
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72- 150 (128.92/83.18) RHLQCRPSDGKWvlsDETPLMPITEAHGGHALTH..LSWNEAGSDLA.VVDVTGRVSVYHIP.FAL.......N..SVNGLRQPAF..SPDDGS
162- 237 (110.38/75.34) RSLLYQNPDGRW...DDISVDLKSTSYSDRLLSHaaLVATQNGILVA.TYSVCQKIRFYRVQ.INW.......NppQWDPAQQPKQ..TP....
370- 432 (54.02/26.74) ..........................YSDRYVIS..VDQIEYGNVVAiTYD.DSSVSFYDPKtMALfngvddaN..TVTGLAQAGFhyAPDASG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 97.14| 29| 277| 2| 32| 2
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2- 32 (44.57/35.39) PLMMDDSINvDDLFgEPTSLELGLPPSASPA
269- 297 (52.56/32.01) PDMMHQSIS.NPLY.TLSRLDIILPASDNAA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 109.51| 29| 237| 303| 345| 3
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303- 332 (55.12/30.51) PWIVAVFSTPPQAT...PDHPGPQGPASViVRW
541- 570 (44.54/18.18) PYIPKCLSI..QAAlgfADKYKPRSFASS.VSW
588- 600 ( 9.85/17.93) ......YNKGIQAE...PHDPG...........
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