<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28291

Description Uncharacterized protein
SequenceEKGQHLGSSSKKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERYQDDIKARQMMHEALQLRLNLVGGMFDTVQRSTQWTTDWALLLLQIITSGTVDMQTNNELFTTVLDMLGVLINGTLASDLSSSSQGGAEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIAGFDSIDKKQGLQVSTKQKVSPWDLFEGHKNPAPLSWAWFGTVRVDRKVIKYEEQHHLLLYHTHPTPKPRSYYLEPLPLPPEEEDEEPATPVSQEPERKSAELSDQGKTTADEEKKTKGRKRKTKSNSRVDEYPQNNIYRVPPNYSPISSQMMHHPQSALWGYNIMGQPQQPGFFLQNQSLAPGGSRLDPTGSFVPTNTKQALSNMLQRRSGTMMQPPSIHAITSQQQLIQMKLMQQQQQQQQQQQRLLRQQAQTRPFQQSDTQSVVHLSPSSIYYSGLQQAQAMPHGYTMYSTQMPLQPQQQAGGVVLSPGYNPRTYPATHSNPALMERLRQMQQQPPSGYIQQQAAAAAAYLQPLPGSQRLTHQPLQQSPLVGGGLDAVLTTAPHPNLNSVPLPQDQMRQRQQQIRQQRLLQLQQQQQQQPQQQQQQQQPQQQQQQQQQPQQQQQQQQQQQQPQGQQTLGLQPMQPQQP
Length685
PositionKinase
OrganismSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
KingdomMetazoa
Lineage
Aromaticity0.05
Grand average of hydropathy-0.955
Instability index75.96
Isoelectric point9.41
Molecular weight77901.90
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28291
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     421.04|     118|     206|     338|     485|       1
---------------------------------------------------------------------------
  285-  386 (84.69/26.02)	SYYLEPLPLP........PEEEDE..EP..ATP...............................................................................vsqeperksaelsdqgkttadeekktkgrkrkTKSNSRvdeypqnniyrVPPNYSPISSQMMHHPQSALW......GYNIMG....QP................QQP
  387-  552 (172.65/58.46)	GFFLQNQSLA........PGGSRL..DP..TGSFVPTntkqALSNMLqrrsGTMMQP.......PSIHAITSQQQLIQMKLMQ.QQQQQQQQQQrllrQQAQTRPFQQSDTQ.................svvhlspssiyysglQQAQAM............PHGYTMYSTQMPLQPQQQAGgvvlspGYNPRT....YPathsnpalmerlrqmqQQP
  555-  685 (163.70/40.18)	GY.IQQQAAAaaaylqplPGSQRLthQPlqQSPLVGG....GLDAVL....TTAPHPnlnsvplPQDQMRQRQQQIRQQRLLQlQQQQQQQPQQ....QQQQQQPQQQQQQQ.................................................QQPQQQQQQQQQQQQPQ..........GQQTLGlqpmQP................QQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     141.26|      34|      37|     215|     248|       2
---------------------------------------------------------------------------
  179-  214 (33.04/17.40)	...ES..IDKVRQLLPLPKQtcdviTCEPMGsLIDTKGNK.I
  215-  248 (60.33/38.39)	AGFDS..IDKKQGLQVSTKQ.....KVSPWD.LFEGHKNPAP
  252-  283 (47.89/28.82)	AWFGTvrVDRK....VIKYE.....EQHHLL.LYHTHPTPKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.40|      22|      23|      82|     104|       3
---------------------------------------------------------------------------
   82-  104 (34.50/25.44)	LQLrLNLV.GGMFDTVQRSTQWTT
  108-  130 (31.90/18.39)	LLL.LQIItSGTVDMQTNNELFTT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28291 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PQQQAGGVVLSPGYNPRTYPATHSNPALMERLRQMQQQPPSGYIQQQAAAAA
2) QMKLMQQQQQQQQQQQRLLRQQAQTRPFQQSDTQ
3) QPGFFLQNQSLAPGGSRLDPTGSFVPTNTKQALSNMLQRRSGTMMQPPSIHAI
4) RSYYLEPLPLPPEEEDEEPATPVSQEPERKSAELSDQGKTTADEEKKTKGRKRKTKSNSRVDEYPQNNIYRVPPNYSPISSQMMHHPQSALWGYNIMGQP
5) YLQPLPGSQRLTHQPLQQSPLVGGGLDAVLTTAPHPNLNSVPLPQDQMRQRQQQIRQQRLLQLQQQQQQQPQQQQQQQQPQQQQQQQQQPQQQQQQQQQQQQPQGQQTLGLQPMQPQQP
514
445
385
284
567
565
478
437
383
685










Molecular Recognition Features






MoRF SequenceStartStop




1) QPQQQQQQQQPQQQQQQQQQPQQQQQQQQQQQQPQGQQTLGLQPMQPQQP
2) RSYYLEPLPLPP
636
284
685
295