<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28282

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCIQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTIASAERLREGTTAGEKQLTMCLQRLHKILSSTKNRALLHIAKLEEASSWTAIEQSLLKLGDTFASLNNSHLQSQAEECGALVRSIPIMLSMHSEQLHKTGFPTVHAVVLLEGTMNLTGEMQPLVEQLMMVKRMQRIPSPLFILEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGDKDFTEDVNCAFEFLLKLTPLLDRADQRCNCDCINLLLQECSKQGLLSEMNKDSLTEKRIADREQSPWLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIRNDGKFPWVMGESTKVAPFLSLVSIFSLMRIWKKIGGRHGIERRIGKSFARCGDEALFWCDVTYNPNAKTDTVRKHRFQPLPTVSVAPGSFLTQVPSFHSLNEFTKHINELCPLVLFVTLILLLGKEGGIKGGGLHENLWGTPVIQLKPSCPQPWASQTSHLGIRSEERRVQMIRQLVGPLSSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPCTGMDTMPYWNLLPPKRPIKEVLTSIFAEVLEKGWVDSRSIHVFDTLLHMGGVYWFCNNLVKELLKETRKEYTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSAKWQSLMDPPGTALAKLAVWCALSSYSTHKGQASSRQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEDDANVLSSPTDRSMNSSLSASQLHTVNMRDPLNRVLANLFLLISSILGARTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRRVAAKAIAAL
Length984
PositionTail
OrganismSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Metatheria> Dasyuromorphia> Dasyuridae> Sarcophilus.
Aromaticity0.07
Grand average of hydropathy-0.025
Instability index49.22
Isoelectric point8.49
Molecular weight110257.40
Publications
PubMed=21709235

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28282
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     144.94|      41|     418|     184|     230|       3
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   95-  129 (55.80/29.13)	....QALL....DIMDMFCDRLSCH....GKAEECIGLCRAL..LSALH
  147-  182 (24.67/16.31)	TAGEKQLTmclqRLHKILSSTKNRALLhiAKLEEAS.............
  185-  227 (64.47/46.46)	TAIEQSLL....KLGDTFASLNNSHLQ..SQAEECGALVRSIpiMLSMH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     179.47|      58|     259|     620|     685|       4
---------------------------------------------------------------------------
  620-  685 (89.73/74.31)	ASQTSHLGIRSEERRV.....QMIRQLVGPLSSENTLQFynervviMSSILEHmCADVLQQ..TATQIKF.PCT
  880-  945 (89.74/55.95)	ASQLHTVNMRDPLNRVlanlfLLISSILGARTAGPHTQF.......VQWFMEE.CVDCLEQgsRGSILQFmPFT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.79|      19|     186|     582|     604|       5
---------------------------------------------------------------------------
  582-  604 (30.68/32.25)	VTLILLlgkeGGIKGGGLHENL.W
  774-  793 (31.12/20.82)	VTLVLL....GHILPGLLTDSAkW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.53|      14|     194|     493|     525|       7
---------------------------------------------------------------------------
  457-  485 (12.98/32.37)	KSFARkfirndgkfpwvMGEStkvAPFLS
  511-  524 (30.56/11.84)	KSFAR............CGDE...ALFWC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.37|      20|     286|      22|      43|      10
---------------------------------------------------------------------------
   22-   43 (30.28/22.03)	QWAINMKKfFPKGA...TWDIlNLA
  310-  332 (31.09/14.31)	QVLVKLKK.YPQGDkdfTEDV.NCA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28282 with Med24 domain of Kingdom Metazoa
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