<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28276

Description Uncharacterized protein
SequenceIHNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVTQNEPVPRGLPNPPGSANGGAHNCRPDVSPATVPGSKPIHELKNRNDIQKLNSPKTEKLGNRKRKGEHRDGHQGPPSKVSKASHELLQNSSPLPTNGIGGSPENFPSPLDVNLHTGPESSRTEHSENDKHSKIPVNAVKPHTSSPGLVKPSSTSSQLKTTVLQHHEKPEEPTGQHQPKSPRCSFSPSNLRHEPFVRQHPTYAPKGSLPSPSQRSHFLDATQASSPSSRAPSLMQPSTPPVPAKRPEASHQTGVETSQHWQEHTSSESHQRHLGTLQHVSPGCKVSSPPGETLMPRVGFSPEASKMDSDDNAASGSDSKKKKRYRSRDYTVNLDGQVLEGGVKPVRLKERKITFDPMTGQIKPLTQKDSLQVDIPALADQHRTEPDKPEQKTNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRREARKTHVLVPNSISTDLPGVSREVTNDDLNRIRQLHWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length588
PositionUnknown
OrganismSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Metatheria> Dasyuromorphia> Dasyuridae> Sarcophilus.
Aromaticity0.04
Grand average of hydropathy-0.991
Instability index59.83
Isoelectric point9.20
Molecular weight65289.13
Publications
PubMed=21709235

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28276
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     188.34|      35|      50|     153|     187|       1
---------------------------------------------------------------------------
   74-  103 (44.80/15.40)	..PNPPGSA......NG..GAHNC.RP.DVSP...ATVP.G..SKPIH
  115-  147 (41.75/13.90)	NSP.KTEKL......GN..RKR...KGEHRDG...HQGPPSkvSKASH
  153-  187 (65.27/25.44)	SSPLPTNGI......GG..SPENFPSPLDVNL...HTGPES..SRTEH
  193-  238 (36.52/11.34)	HSKIPVNAVkphtssPGlvKPSSTSSQLKTTVlqhHEKPEE..PTGQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.52|      31|      60|     449|     480|       2
---------------------------------------------------------------------------
  449-  480 (50.49/32.92)	KPEQKTNLQSPFE.QTNWKELSRnEIIQSYLNR
  511-  542 (48.03/26.78)	REARKTHVLVPNSiSTDLPGVSR.EVTNDDLNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.27|      37|      41|     262|     301|       3
---------------------------------------------------------------------------
  239-  294 (52.89/30.78)	QPKSPrcsfspsnlrhepfvrqhPTYAPKGSLP..............SPSQRSHfLDATQASSPSSRAPS
  297-  349 (55.38/23.02)	QPSTP................pvPAKRPEASHQtgvetsqhwqehtsSESHQRH.LGTLQHVSPGCKVSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.44|      16|      18|     393|     410|       4
---------------------------------------------------------------------------
  393-  410 (22.20/16.76)	VNLDGqvLEGGVKPVRLK
  414-  429 (29.24/15.94)	ITFDP..MTGQIKPLTQK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28276 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PVRLKERKITFDPMTGQIKPLTQKDSLQVDIPALADQHRTEPDKPEQKTNLQSPFEQ
2) SWQKLIEPVTQNEPVPRGLPNPPGSANGGAHNCRPDVSPATVPGSKPIHELKNRNDIQKLNSPKTEKLGNRKRKGEHRDGHQGPPSKVSKASHELLQNSSPLPTNGIGGSPENFPSPLDVNLHTGPESSRTEHSENDKHSKIPVNAVKPHTSSPGLVKPSSTSSQLKTTVLQHHEKPEEPTGQHQPKSPRCSFSPSNLRHEPFVRQHPTYAPKGSLPSPSQRSHFLDATQASSPSSRAPSLMQPSTPPVPAKRPEASHQTGVETSQHWQEHTSSESHQRHLGTLQHVSPGCKVSSPPGETLMPRVGFSPEASKMDSDDNAASGSDSKKKKRYRSRDYTVNLDGQVLEGGV
406
55
462
404










Molecular Recognition Features






MoRF SequenceStartStop




NANANA