<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28259

Description Uncharacterized protein
SequenceERKERKNYQLTQHEINGLTFFSPPISFQLLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKGDKYNQQQQNQHQQQTAPQQPQQAAPPPPQQQQQQQQQQNSTQTNGTGAGAGAGAGGTGAGLQHSQDSGLNPVPPNKKPRLGPSGTNSGGPVMPSEYQHSSSRLSYQSNVQGSSQSQSTMGYSSSSQQSSQYHPTHQAHRY
Length468
PositionKinase
OrganismSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
KingdomMetazoa
Lineage
Aromaticity0.09
Grand average of hydropathy-0.782
Instability index57.21
Isoelectric point8.93
Molecular weight53353.51
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28259
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.34|      20|      22|     333|     352|       1
---------------------------------------------------------------------------
  333-  352 (38.34/19.43)	QQQQNQHQQQTAPQQPQQAA
  357-  376 (37.00/18.51)	QQQQQQQQQQNSTQTNGTGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.88|      18|      36|     379|     397|       2
---------------------------------------------------------------------------
  379-  397 (28.84/19.02)	GAGAGG..TGAGLQHSQdSGL
  412-  431 (30.04/15.28)	GTNSGGpvMPSEYQHSS.SRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      92.11|      30|      36|     239|     269|       3
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  239-  269 (48.62/34.66)	LQK....D.FRRTTYANSSLIKYMEKHKVkPDSKVF
  272-  306 (43.48/26.20)	LQKlltmDpTKRITSEQALQDPYFQEDPL.PTSDVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.44|      15|      36|     111|     125|       4
---------------------------------------------------------------------------
  111-  125 (26.77/22.98)	DLKPANILVMGEGPE
  149-  163 (28.67/25.22)	DLDPVVVTFWYRAPE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28259 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TKRITSEQALQDPYFQEDPLPTSDVFAGCQIPYPKREFLNEDEPEEKGDKYNQQQQNQHQQQTAPQQPQQAAPPPPQQQQQQQQQQNSTQTNGTGAGAGAGAGGTGAGLQHSQDSGLNPVPPNKKPRLGPSGTNSGGPVMPSEYQHSSSRLSYQSNVQGSSQSQSTMGYSSSSQQSSQYHPTHQAHRY
281
468










Molecular Recognition Features






MoRF SequenceStartStop




1) LSYQS
2) PNKKPRLG
3) QYHPTHQAHRY
431
402
458
435
409
468