<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28239

Description Uncharacterized protein
SequenceMTAAPASPQQIRDRLLQAIDAQSNIRNMVAVLEVISSLEKYPITKEALEETRLGKLINDVRKKTKNEELAKRAKKLLRSWQKLIEPVHQGEAALRGLPGTAGSANGGAHNCRPEAGAAVGPRSIRDLKSRNDIQRLPGQRLDRPGSRKRRGDQRDLGHPGPPPKASKTSHEPLAPSSSPLPTNGISGSPESFTGPLDSGGHTGPEGSRLEPGENDKHSGWIPVNAVRPHTSSPGPGLGAKAASLQPLDRVDETPGAPHHRGPPRCSFSPRNSRHEGPFARQRSPYVPKGSVPSPSPRPPSVEATQAPSPLPLAQPPTPPVRRLELLPNSESPGRWPDQPEGHQRLAGPGCKAGLSPDSSRADSDAASSGGSDSRKKKRYRPRDYTVNLDGQGAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVQAESPVRTEPSRTELDAQEPKGGLQSPFEQTNWKELSRNEMIQSYLSRQSSLLSSSGAQTPGAHHFMSEYLRQEESAKRHSARETHVLAPHSPPADLPGHTREVTQDDLERIQAHQWPGVNGCYDTQGTWYDWTQCIALDPHGDDGRLNILPYVCLD
Length582
PositionUnknown
OrganismLoxodonta africana (African elephant)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Afrotheria> Proboscidea> Elephantidae> Loxodonta.
Aromaticity0.04
Grand average of hydropathy-0.938
Instability index63.16
Isoelectric point9.40
Molecular weight63358.98
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28239
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     478.49|     109|     112|     140|     251|       1
---------------------------------------------------------------------------
   63-  131 (88.88/23.70)	........................................................KTKNEELAKRAKKLLR......SWQKLIEPV....HQGEAALRGLPGTAGSANG...GAHNCRPEA...GAAVGPR..SIRD.LKSRN
  140-  249 (182.57/60.57)	RLDR.PGS...RKRRGD......QRDL.....GH...PGP......P..P...KASKTSHEPLAPSSSPLPTN.GISGSPESFTGPLDSGGHTGPEGSRLEPGENDKHSG.WiPVNAVRPHTSSPGPGLGAKaaSLQP.LDR..
  250-  362 (132.32/38.59)	.VDEtPGA...PHHRGPprcsfsPRNS.....RH...EGPfarqrsPyvP...KGS.......VPSPSPRPPSvEATQAP....SPLPLAQPPTPPVRRLELLPNSESPGrW.P.DQPEGHQRLAGPGCKA...GLSPdSSRAD
  365-  448 (74.72/18.43)	AASS.GGSdsrKKKRYR......PRDYtvnldGQgaeAGV......K..PvrlKERKLTFDPMTRQIKPLTQK.....EPVQAESPVRT......EPSRTELDAQEPKGG..................................
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28239 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SYLSRQSSLLSSSGAQTPGAHHFMSEYLRQEESAKRHSARETHVLAPHSPPADLPGHTREVTQDDLERI
2) VHQGEAALRGLPGTAGSANGGAHNCRPEAGAAVGPRSIRDLKSRNDIQRLPGQRLDRPGSRKRRGDQRDLGHPGPPPKASKTSHEPLAPSSSPLPTNGISGSPESFTGPLDSGGHTGPEGSRLEPGENDKHSGWIPVNAVRPHTSSPGPGLGAKAASLQPLDRVDETPGAPHHRGPPRCSFSPRNSRHEGPFARQRSPYVPKGSVPSPSPRPPSVEATQAPSPLPLAQPPTPPVRRLELLPNSESPGRWPDQPEGHQRLAGPGCKAGLSPDSSRADSDAASSGGSDSRKKKRYRPRDYTVNLDGQGAEAGVKPVRLKERKLTFDPMTRQIKPLTQKEPVQAESPVRTEPSRTELDAQEPKGGLQSPFEQTNWKELS
469
87
537
462










Molecular Recognition Features






MoRF SequenceStartStop




1) KPVRLKERKL
2) RKKKRYRPRDYTVNLDGQ
3) RRLELL
398
374
321
407
391
326