<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28209

Description Mediator complex subunit 25
SequenceMVPGSEGPARAGGLVADVVFVIEGTANLGPYFEGLRKHYLLPAIDLRPRPPTLTAFGGDYGGTQYSLVVFNTVDCAPESYVQCHAPTSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGYTTENLVQKIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPLTDVSQDPRHMVLVRGLVLPVGGSSAPGPLQPKQPVPLPPAPTSGAALSAAPQQPLPPVPQQYQVPGNLSAAQVAAQNAVEAAKSQKAGLGPRFSPINPLQQAAPGVGPPFSQPTAPPLPPGPPGAPKPPPVSQPSLVSSVAPGSGLAPPAQPGASSMAGSVAPGGVSGPSPAQLGTPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDASTKLTRSLPCQVYVNHGENLKTDQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFYFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGGQQAPPGLGPILEDQARPTQNLLQLRPPQPQPPGAVGASGAAGQPQPQGAAQAPSGAPQGPPGAGTGPPPPGPILRPQNPGANPQLRSLLLNPPPVSFAGRGRWGRRVPAPDTGGPLSWERQSGLLSGVGVALCQLRPSLSSMQSLPHCPPGQMLLSGGPRGPVPQPGLQPSVMEDDILMDLI
Length741
PositionUnknown
OrganismLoxodonta africana (African elephant)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Afrotheria> Proboscidea> Elephantidae> Loxodonta.
Aromaticity0.06
Grand average of hydropathy-0.195
Instability index56.73
Isoelectric point9.23
Molecular weight77678.43
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28209
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     390.63|      60|      62|     558|     617|       2
---------------------------------------------------------------------------
  195-  255 (48.33/ 7.27)	.EKA.......APPAlLEPLqpLTDVSQDPRHMVLVR...GLVLP....V....GGSSAPGplQPkQPVPLPPAPtSGAA.
  345-  383 (47.05/ 6.92)	......................LVSSVAPGSGL...AP..P.AQP.........GASSMAG..SV.AP.GGVSGP.SPAQL
  389-  450 (46.29/ 6.71)	GGQQsvsnkllAWSG....V..LEWQEKPKPASVDAST..KLTRSlPCQVyvnhGENLKTD..Q..WPQKLI.......MQ
  452-  505 (66.78/12.36)	IPQQ.......LLTT.LGPL..FRN.SR....MVQFYF..TNKDL.ESLK....GLYRIMG..NG.FA.GCVHFP.HTAPC
  558-  617 (115.59/25.81)	GGQQ.......APPG.LGPI..LEDQARPTQNLLQLRP..PQPQP.PGAV....GASGAAG..QP.QPQGAAQAP.SGAPQ
  621-  674 (66.60/12.31)	GAGT.......GPPP.PGPI..LRPQ.NPGAN.PQLRSllLNP.P.PVSF....AGRGRWG..RR.VP.....APdTGGP.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.77|      24|     384|     320|     344|       3
---------------------------------------------------------------------------
  320-  344 (48.75/13.35)	SQPTAPP....LPPGPPGaPKPPPVSQPS
  703-  730 (43.02/ 9.21)	SLPHCPPgqmlLSGGPRG.PVPQPGLQPS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28209 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSSAPGPLQPKQPVPLPPAPTSGAALSAAPQQPLPPVPQQYQVPGNLSAAQVAAQNAVEAAKSQKAGLGPRFSPINPLQQAAPGVGPPFSQPTAPPLPPGPPGAPKPPPVSQPSLVSSVAPGSGLAPPAQPGASSMAGSVAPGGVSGPSPAQLGTPALG
2) HKQVQQQKLEQQRGMGGQQAPPGLGPILEDQARPTQNLLQLRPPQPQPPGAVGASGAAGQPQPQGAAQAPSGAPQGPPGAGTGPPPPGPILRPQNPGANPQLRSLLLNPPPVSFAGRGRWGRRVPAPDTGGPLSWERQ
3) LSSMQSLPHCPPGQMLLSGGPRGPVPQPGLQPSV
231
543
698
389
680
731










Molecular Recognition Features






MoRF SequenceStartStop




NANANA