<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28197

Description Mediator complex subunit 23
SequenceMVQMETQLQSIFEEVVKTEIIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWAGLSQESHEQCIQWIVKFVHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYCAEHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTSCLASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITYFSKQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPIQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRERPTLKRKLVHAIIGSLKDNRPQGWCLSDTYLKSAMNAREDNPWIPDDSYYCRLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKDVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVHVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSAHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLNPALKLRLRFITHISKMEPAAVPPQGLNSGSPAPQPNQVPVSLPVTQ
Length1377
PositionTail
OrganismLoxodonta africana (African elephant)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Afrotheria> Proboscidea> Elephantidae> Loxodonta.
Aromaticity0.10
Grand average of hydropathy-0.006
Instability index45.78
Isoelectric point7.00
Molecular weight157407.29
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28197
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.38|      16|      18|     287|     304|       2
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  287-  302 (30.88/24.15)	CNMLG..LNKQVLYCAEH
  306-  323 (23.50/ 9.53)	CPVLEdqLVDLVVYAMER
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.19|      17|      19|     247|     265|       3
---------------------------------------------------------------------------
  247-  265 (28.43/23.59)	DP..ATLRFPLKGllPYDKDL
  267-  285 (27.76/16.15)	EPqtALLRYVLEQ..PYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.11|       8|      18|    1048|    1057|       4
---------------------------------------------------------------------------
 1048- 1057 (14.23/12.73)	PqgWCLSDTY
 1069- 1076 (18.88/ 9.08)	P..WIPDDSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.37|      25|      80|     387|     421|       5
---------------------------------------------------------------------------
  174-  200 (39.44/16.95)	LERNAclLPAYFAVTEIRK.LYPEGK.LP
  393-  419 (35.93/28.44)	IQKNA..LADFLPVMKLFDlLYPEKEcIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     178.90|      63|      80|     456|     534|       6
---------------------------------------------------------------------------
  456-  534 (99.99/112.82)	IPHSLRLHHEF.LQQSLRNKSLQMNDYK..IALLCnaystnsecftlpmgALVETiYG.............NGIMRIPLPGT.SCLASGSI.TPLPM
  536-  616 (78.91/56.65)	LLDSLTVHAKMsLIHSIATRVIKLAHAKssVALAP...............ALVET.YSrllvymeieslgiKGFISQLLPTVfKSHAWGILhTLLEM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.34|      17|      20|     903|     920|       7
---------------------------------------------------------------------------
  903-  920 (26.47/20.43)	NDFRNRVSDFVKENsPEH
  924-  940 (34.87/22.44)	NDWHTKHMNYHKKY.PEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.85|      28|     619|     691|     718|       9
---------------------------------------------------------------------------
  691-  718 (47.05/31.25)	ELNRALILTLARATHVTDFFTGSDSIQG
 1329- 1356 (49.80/33.52)	NLNPALKLRLRFITHISKMEPAAVPPQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.82|      12|      20|     360|     371|      10
---------------------------------------------------------------------------
  360-  371 (21.06/12.22)	HMVLSLHQKLAG
  380-  391 (22.76/13.82)	HLMWVLLQFISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.77|      16|      20|     941|     956|      13
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  941-  956 (28.12/13.84)	LYFEGLAEQVDPPIQI
  963-  978 (29.65/14.94)	IYFGNVCLRFLPVFDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.07|      51|     716|      25|      92|      16
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   32-   92 (82.93/82.44)	TPEDEKTKLISCL.GAFRQF........................WAGLSQESHeqciqwIVKFVHGQHSPKrisfLYDCL..AMAVET
  732-  809 (76.14/39.62)	TPHNWASHTLSCFpGPLQAFfkqnnvpqesrfnlkknveeeyrkWKSMSNEND......IITYFSKQGSPP....LFLCLlwKMLLET
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28197 with Med23 domain of Kingdom Metazoa
Unable to open file!