<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28138

Description Uncharacterized protein
SequenceMAAFGILSYEHRPLKRPRLGPPDVYPQDPKQKEDELTALNVKQGFNNQPAVSGDEHGSAKNVNFNPSKISSNFSSIIAEKLRYNTFPDTGKRKPQVNQKDNFWLVTARSQSSINNWFTDLAGTKPLTQLAKKVPIFSKKEEVFGYLAKYLVPVMRSAWMIKMTCAYHAAITETKVKKRHVIDPCIEWTQIITKYLWEQLQKVAEFYRQFPSQGCSSPLPATPADVETAMKQWEYNEKLAMFMFQDGMLDRHEFLTWVLECFEKVRPGEDELLRLLLPLLLQYSGEFVQSAYLSRRLAYFCTRRLNLLLSDGSLGPGTGGHPAHGMLTQQGNALPPTPTSQPAGGNQPQTAFTDFYICPQHRPLVFGLSCMLQSIVLCCPSALVWHYSLTDSRNKTGSPLDLLPIAPSSLPMPGGNTAFTQQVRTKLREIEEQVKERGQAVEFRWSFDKCQETTAGFTIGRVLHTLEVLDNHSFEKSDFNNSLDSLYNRIFGSGQSKDGHEMSPDDDAVVTLLCEWAVCCKRSGRHRAMVVAKLLEKRQAEIEAERCGESEVVDEKGSVSSGSLSAATLPVFQDVLLQFLDTQAPTLTEPGNESERVEFSNLVLLFCELIRHDVFSHNIYMCTLISRGDLATDSHLPRPRSPSDEPSDESERKEQDAGSGIKMEDTGLSESMEIDHNSSANFDEMFSPPMHCETKGSPSPEKPAAEPDSKAGCKDKGTDPAFPQLYEQPRHIQYATHFPIPQEESASHECNQRLVVLYGVGKLRDEARHTIKKITKDILKVLNRKSEAETEGEEGQKRKRSKPEAFLTTEDIFSKFQHLSHFDQHQVTSQVSRNVLEQINSFALGMSYLLPLVPHIQFIFDLMEYSLNISGLIDFAIQLLNELSLVEAELLLKSSNLVGIYTTGLCLCIVAVLRRYHSCLILNPDQTAQVFDGLRIVVKSGVNPADCSSSERCILAYLYDVYTSCSHLKNKFGEIFSEFCSKVKNSIYCNIDPSDSNMLWDPVFMMEAIANPCAPNFNHSMVGKILNDSPANRYSFVCNVLMDVCVDHRDPERVNDIGILCAELTAYCRSLSAEWLGILKALCCSSNNGNCGFNDLLCNVDVSDLSFHDSLATFVAILIARQCLLLEDLVRCVAIPSLLNAACSEQDSEPGARLTCRILLHLFKTPQRNPFPQEVVKSDKSSVGIRWSCDRHLLAASQNSIVVGAVFAVLKAVFMLGDAELRGSGLSHPAGLDDISEGRNVSIETASLDVYAKYVLKTICQQEWVGERCLKSLSEDSSALQDPVLVNIQAQRLLQLICYPHRQLDSDDGDNPQRQRIKRILQNMDQWTMRQSSLELQLMIKQSTNNELYSLLENIAKATIEVFQKSAEMNSNPSGNGAAAQGGSGSNNSSSSKMKPILSSSERSGVWLVAPLIAKLPTSVQGHVLKAAGEELEKGQHLGSSSRKERDRQKQKSMSLLSQQPFLSLVLTCLKGQDEQREGLLTSLYSQVQQIVTNWREDQYQDDCKAKQMMHEALKLRLNLVGGMFDTVQRSTQQTTEWAVLLLDIISSGTVDMQSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLVKKLRKELGDRQSESLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFEKEGLQVSTKQKISPWDVFEGLKHSAPLSWGWFGTVRVDRKVTKFEEQQRFLLYHTHLKPKPRSYYLEPLPLPPEEEEPLTPVSQEPEKKMMEVVKPEKSVPAVPSESNKKKPSKKKKNPIVKTEDYVNRTPGGGPYGTNMPPELNPYGRLQYGQQAMNMYTQNQPLPPGGPGLEPPYRPTRNPQMNKMMPTRPSYPGMMPSMQGSMTGMMGMDKQYPMGYKPQPNIVPGQTMRQHLQVRLNQSMAGQQIRQITPNQPYTSMQASQFASQGYTTYGSHMGMQQHPSQGGGIVPSSYGNQNFQGTHPGANPAVVDPLRQMQQRPSGYVHQQAPGYAHNMQNTQRFAHQPMQQNPIMHSLSHMGGQGVHPSLRPNPMLTVAQQQFLRQQALRRNLQICASNTNHFFVFPMFPQQQQQAQQQQVQPQQVPSQQQVQQQQQVTAGPPPGQQQNQGLGMQPLPPQQPMFPRQGMQQTQQQQQTAALVRQLQQQLSNTQPGQGTNSYY
Length2150
PositionKinase
OrganismGasterosteus aculeatus (Three-spined stickleback)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Perciformes> Cottioidei> Gasterosteales> Gasterosteidae> Gasterosteus.
Aromaticity0.07
Grand average of hydropathy-0.478
Instability index53.25
Isoelectric point6.85
Molecular weight240799.42
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
beta-catenin binding	GO:0008013	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28138
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.52|      12|      15|    1907|    1919|       2
---------------------------------------------------------------------------
 1905- 1917 (14.38/ 6.96)	QPYTSmQASQFAS
 2103- 2114 (23.14/ 8.25)	QPLPP.QQPMFPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.03|      12|      15|     855|     866|       3
---------------------------------------------------------------------------
  855-  866 (23.39/15.76)	IQFIFDLM.EYSL
  872-  884 (14.64/ 6.79)	IDFAIQLLnELSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.66|      14|      15|    1640|    1654|       4
---------------------------------------------------------------------------
 1640- 1654 (20.41/18.49)	TKgNKIAGFEK.EGLQ
 1657- 1671 (22.26/13.72)	TK.QKISPWDVfEGLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.20|      30|      54|     636|     665|       5
---------------------------------------------------------------------------
  636-  665 (53.36/24.35)	PRPRSPSDEPSDESERKEQDAGSGIKMEDT
  688-  717 (52.84/24.04)	PMHCETKGSPSPEKPAAEPDSKAGCKDKGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     119.58|      24|      26|    1722|    1746|       6
---------------------------------------------------------------------------
 1722- 1744 (33.94/15.95)	........PEEEE..P.LTPVSQEPEKKMMEVVK
 1745- 1771 (24.28/10.82)	PeksvpavPSESN..K.KKP....SKKKKNPIVK
 1820- 1841 (35.12/16.82)	........PGLEP..P.YRPTRNPQMNKMMP.TR
 1842- 1863 (26.23/10.55)	P............syPgMMPSMQGSMTGMMGMDK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.60|      20|      54|    2070|    2093|       7
---------------------------------------------------------------------------
 1977- 1996 (33.80/ 8.55)	QQAPGYAHNMQNTQRFAHQP
 2072- 2091 (37.80/20.05)	QQVPSQQQVQQQQQVTAGPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.38|      14|      15|    1918|    1931|       8
---------------------------------------------------------------------------
 1918- 1931 (29.79/15.11)	QGYTTYGSHMGMQQ
 1935- 1948 (25.59/11.97)	QGGGIVPSSYGNQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     168.38|      40|     345|     990|    1029|       9
---------------------------------------------------------------------------
  990- 1029 (76.18/48.97)	IDPSDSNMLWDPVFM.MEA...IANPCAPNFNHSMVGKILNDSP
 1275- 1311 (40.19/22.02)	....DSSALQDPVLVnIQAqrlLQLICYP...HRQLDSDDGDNP
 1339- 1372 (52.01/30.87)	IKQSTNNELYS...L.LEN...IAKATIEVFQKSAE...MNSNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.55|      23|     344|     243|     265|      10
---------------------------------------------------------------------------
  243-  265 (44.70/25.96)	FQDGML.................DRHEFLTWVLECFEKVR
  571-  610 (28.86/14.30)	FQDVLLqfldtqaptltepgnesERVEFSNLVLLFCELIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.24|      21|      24|    1532|    1554|      11
---------------------------------------------------------------------------
 1532- 1554 (30.70/30.56)	QQTTewAVL.LLDIISSGTV..DMQS
 1557- 1580 (26.54/16.89)	ELFT..TVLdMLSVLINGTLaaDMSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.39|      26|     104|    1586|    1622|      26
---------------------------------------------------------------------------
 1586- 1622 (34.08/49.32)	MEENKRAYM...NLVKKLRkelgdrqSESLEKvrqlLPLP
 1693- 1721 (45.32/30.95)	FEEQQRFLLyhtHLKPKPR.......SYYLEP....LPLP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28138 with Med12 domain of Kingdom Metazoa
Unable to open file!