<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28135

Description Mediator complex subunit 28
SequenceMASSMSGMFSGQQPPGVHPVGGPGVPGQPGFPGTAARGPVNNTLVDELEASFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDVARQTECFFLQKRLQLSVQKPEQVVKEDVSELRNELQRKELLVQKHLSKLHHWQQVLEDVSVQHRKPTDLPPSGPLAFLEQASASLPPAPLKPN
Length180
PositionHead
OrganismGasterosteus aculeatus (Three-spined stickleback)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Perciformes> Cottioidei> Gasterosteales> Gasterosteidae> Gasterosteus.
Aromaticity0.06
Grand average of hydropathy-0.437
Instability index51.10
Isoelectric point5.51
Molecular weight19718.10
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28135
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.02|      25|      30|      90|     116|       1
---------------------------------------------------------------------------
   90-  116 (34.90/25.64)	QTECFFLQKRLQlSVQKPEQVVkEDVS
  123-  147 (44.12/23.86)	QRKELLVQKHLS.KLHHWQQVL.EDVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.53|      19|      22|      37|      55|       3
---------------------------------------------------------------------------
   37-   55 (32.46/21.56)	RGPVNNTLVDELEASFEAC
   62-   80 (34.07/22.91)	QDYVNGTDQEEIRTGVDQC
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28135 with Med28 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) SSMSGMFSGQQPPGVHPVGGPGVPGQPGFPGTAARGPV
3
40

Molecular Recognition Features

MoRF SequenceStartStop
NANANA