<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28123

Description Mediator complex subunit 23
SequenceMALSMETQLQSIFEDVVKTEMIEEAFAGMFMDTPEDERTKLISCLGAFRHYWGTLPQESHEQCVQWIVRFIHSQHSPKRISFLHDCLAMAVETSLLPPRMVCVALISSDSLEWERTQLWALTFKLIRKIIGGMDYKGVRDLLKAVLEKIQSIPTTVSSAIVQQLLAAREVVEYILDRNACLLPAYFAIAEIRKMYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTNLHFPLRGMLPFDKDLFEPQTGLLRYVLEQPYSREMVCNMLGLNKQHKQRCPVLEEQLVDLVVYAMERSETEEHFDADIGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHSFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRNKTLGMSDYKIALLCNAYSTNSDCFTLPMGVLVETIYGNGAMRINLPGTNCMASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAQAKSSITLAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGFRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHNKHMSYHKKYPEKLYFEGLADQVNPPMQLQPQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAIMSSLKDNRTPGWCLSETYLKFGMNAREDNVWLPDDTYYCKLIGRLPPMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKDVGNALLNVALKSQPLVPRENITAWMNAIGLVITALPEPYWIVLHDRIVSVIGSPVLTSETEWAGYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCHHLSYMDPICDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRLRFITHSSLIETSSCPPPRSARTRPYKSQPNPRSNSIVSRASPLSLP
Length1380
PositionTail
OrganismGasterosteus aculeatus (Three-spined stickleback)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Perciformes> Cottioidei> Gasterosteales> Gasterosteidae> Gasterosteus.
Aromaticity0.10
Grand average of hydropathy-0.043
Instability index46.70
Isoelectric point7.59
Molecular weight157954.76
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28123
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.83|      48|      83|     669|     724|       3
---------------------------------------------------------------------------
  669-  724 (68.06/65.93)	PQFTRFlsdpktVLSAESEELNRALiLTLARATHVTDFFT..GSDSIH..GTWcKDILQT
  755-  806 (77.77/50.02)	PQESRF......NLKKNVEEEYRKW.KSMANENDIITHFSmqGSPPLFlcLLW.KMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.13|      49|      88|    1201|    1255|       4
---------------------------------------------------------------------------
 1201- 1255 (75.80/67.84)	CHQ.SYSEMNCSYvlaLAHAVWHHSSIGQLSLIPKFLsETLKPIVQteFQLLYVYH
 1290- 1339 (86.34/57.72)	CHHlSYMDPICDF...LYHIKYMYTGDSVKEQVEKII.MTLRPAMK..LRLRFITH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     246.76|      71|     863|      34|     112|       5
---------------------------------------------------------------------------
   34-  112 (114.99/101.23)	PEDERTKLISCL..GAFRHyWgtLPQESHEQCVQWivrfiHSQHSPKRISF..LHD...............CL..AMAVETSLLPPRM..VCVA...............LISSDSLE
  847-  898 (33.12/14.02)	..........................................QQLNKCIEI..LNDmvwkynivtldrlilCL..AMRSHEG..NEAQ..VCYF...............IIQLLLLK
  899-  991 (98.65/65.78)	PNDFRNRVNDFVkeNAPEH.W..LQSDWHNKHMSY.....HKKY.PEKLYFegLAD...............QVnpPMQLQPQYLPIYFgnVCLRflpvfdivihrflelLPVSKSLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.46|      24|     462|     640|     667|       7
---------------------------------------------------------------------------
  640-  667 (36.77/26.70)	PQTNQNQLHL.CVESTALrlitALGSSEV
 1103- 1127 (38.68/19.70)	PNPAAHALHVtCVELMAL....AVSGKDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     121.57|      33|      90|    1068|    1102|      10
---------------------------------------------------------------------------
 1068- 1102 (59.20/45.06)	LPdDTYYCKLIGRLPPMAGkSPGPFPNCDWRFNEF
 1161- 1193 (62.37/38.25)	LP.EPYWIVLHDRIVSVIG.SPVLTSETEWAGYPF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      30|     345|     354|      11
---------------------------------------------------------------------------
  345-  354 (18.69/10.89)	IFFVLFQFAS
  378-  387 (19.45/11.65)	LMWVLLQFIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28123 with Med23 domain of Kingdom Metazoa
Unable to open file!