<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28111

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKKNFPKGATWDYLNLAEALMEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTALSKFDDFSRELCVKSLLEIMDMFCHRLSCHGKAEECIGLCRALLGVVVWLLQGCAWYCEKLGELGPSAGTEASLRACQERLQHLMNSSKNRALVHIARLEDQGGSWSNVEQSVLKVTDGLGSVSNQTLRTKLEESLSLVKGIPMMLSEQSDPKFHASFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQRIPVPLFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPQSDKGQDFMDDVNIAFQYLLKLTPLLDKADQRCNCDCLGMLLQECNKLGLLSDSNTTCLTSKRTDDREFAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSGETPFFETWLQTCMPEDGKTLNPDHPCFRPEPGKVESLVTLLNNSSEMKLVQVKWHEICLSTPAAILEVLNAWENGVLSVEAVQQKITDNIKGKVCSMAICAVAWLVAHVRMLGRDEREKPQTMIRQLVTPLYGENTLQFYNERVIIMSSIMEHMCADVFQQTAATLRPPMEGQEPIPYRNLLPAKDPIHVALSKQFQTVLRKGWADSRALHLFESLLNMGGVFWFTNNLVKELLKETRQEWADRVSELLYSIFCLDTQQISLTLLGTILPDLLTDSAHWHGLADPPGKALAKLSVWCALSSFSSHNRGSFSARQRKRQREDIEDYNSLFPLDDTQPSKLMRLLSSNEDEPAALSSPGDRSMSSSLSASQLHTVNMRDPLHRVLANLFLLISSILGSKMAGPHTQFVQSFMEECVECLEQGSRGSILQFMPFTMVSELVKLPALAKPRVVLAITDLTLPLGRRVAAKAIAAL
Length991
PositionTail
OrganismGasterosteus aculeatus (Three-spined stickleback)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Perciformes> Cottioidei> Gasterosteales> Gasterosteidae> Gasterosteus.
Aromaticity0.07
Grand average of hydropathy-0.064
Instability index44.98
Isoelectric point6.64
Molecular weight110588.19
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
enteric nervous system development	GO:0048484	IEA:Ensembl
interstitial cell of Cajal differentiation	GO:0061453	IEA:Ensembl
retinal cone cell development	GO:0046549	IEA:Ensembl
thymus development	GO:0048538	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28111
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      56.27|      11|      16|     179|     189|       1
---------------------------------------------------------------------------
  161-  171 (17.36/10.10)	RLQHLMNSSKN
  179-  189 (21.62/14.62)	RLEDQGGSWSN
  196-  206 (17.29/10.02)	KVTDGLGSVSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.96|      26|     115|     422|     447|       5
---------------------------------------------------------------------------
  422-  447 (45.57/25.31)	KTVDADHSK.SPE.GLLGVLGHMLSGKS
  538-  565 (38.40/20.28)	KTLNPDHPCfRPEpGKVESLVTLLNNSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.50|      10|      20|     240|     249|       8
---------------------------------------------------------------------------
  240-  249 (17.81/10.73)	PSVHAFIMLE
  260-  269 (16.69/ 9.57)	PLVEQLMMIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.59|      20|      20|     879|     898|       9
---------------------------------------------------------------------------
  879-  898 (32.20/20.91)	RSMSS.SLSASQLHTVNMRDP
  901-  921 (25.39/14.84)	RVLANlFLLISSILGSKMAGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.48|      15|      36|     721|     736|      11
---------------------------------------------------------------------------
  721-  736 (23.85/17.07)	RKGWADsRALHLFESL
  758-  772 (27.62/15.28)	RQEWAD.RVSELLYSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.23|      23|      24|     332|     355|      12
---------------------------------------------------------------------------
  332-  355 (34.65/24.66)	DDVNIAFQYLLKLTpLLDKADQRC
  358-  380 (41.58/24.58)	DCLGMLLQECNKLG.LLSDSNTTC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28111 with Med24 domain of Kingdom Metazoa
Unable to open file!