<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28107

Description "Transcription elongation factor A (SII), 3"
SequenceMTREEDLTRIAKKLDKMVSRNNTEGALDLLRELKSFNMTLKLLQETRIGMSVNGIRKNSTDEEVIALAKLLIKDWKRLLDLEKAAERNNGLDSSKTAVSPKGPPSETHSRKDSKDSSSRHPRPHAPLPASPPARRLSLEVKKERKDSSDSKPPLLKKPSLGVKKEKHRKDSCDSKPGQPVRHKSTDSKPGRRESTDSKKSSSPPAKKLTVERKGKADTPKTPTSPTSPMSPSGSSSGGPVPPHLATGDSVRDKCIYMLAAALRTDDHYKDFGTNCDSMAAEIEDYILQETKATDMKYKNRVRSRISNLKDPKNPGLRRNVLAGSIDLSRIASMSAQEMASDELKQLRNVLTQEAIREHQMAKTGGTSTDLLQCGKCKKRNCTYNQVQTRSADEPMTTFVLCNECGNRWKFC
Length411
PositionUnknown
OrganismGasterosteus aculeatus (Three-spined stickleback)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Eupercaria> Perciformes> Cottioidei> Gasterosteales> Gasterosteidae> Gasterosteus.
Aromaticity0.03
Grand average of hydropathy-0.948
Instability index63.18
Isoelectric point9.70
Molecular weight45650.53
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28107
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     116.29|      21|      21|     131|     151|       1
---------------------------------------------------------------------------
   74-   94 (27.46/ 9.46)	DW.KRLLDLEKAAE..RNNGLDSS
  131-  151 (39.01/15.78)	PP.ARRLSLEVKKE..RKDSSDSK
  152-  175 (28.38/ 9.96)	PPlLKKPSLGVKKEkhRKDSCDSK
  188-  202 (21.44/ 6.17)	KP.GRRESTDSKK........SSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.49|      27|     124|      97|     124|       3
---------------------------------------------------------------------------
   97-  124 (49.17/25.14)	AVSPKGPPSETHSRKDSkDSSSRHP.RPH
  216-  243 (48.32/21.19)	ADTPKTPTSPTSPMSPS.GSSSGGPvPPH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.44|      15|      26|     256|     270|       4
---------------------------------------------------------------------------
  256-  270 (27.56/19.17)	YMLAAALRTDDHYKD
  285-  299 (25.88/17.59)	YILQETKATDMKYKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.06|      12|      26|     368|     379|       5
---------------------------------------------------------------------------
  368-  379 (22.67/14.27)	TDLLQCGKCKKR
  396-  407 (23.39/14.92)	TTFVLCNECGNR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28107 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KAAERNNGLDSSKTAVSPKGPPSETHSRKDSKDSSSRHPRPHAPLPASPPARRLSLEVKKERKDSSDSKPPLLKKPSLGVKKEKHRKDSCDSKPGQPVRHKSTDSKPGRRESTDSKKSSSPPAKKLTVERKGKADTPKTPTSPTSPMSPSGSSSGGPVPPHLATGDS
83
249










Molecular Recognition Features






MoRF SequenceStartStop




1) ARRLSLEVKKERK
133
145