<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28088

Description Serine/threonine-protein kinase domain
SequenceMPLRLRPSAGHESHQQQPQPQNPQLQLRSGNTQWNPSAAAPPMAFTSSSSLSWEGIGRSGGYQPKFRVTERYRIVGFISSGTYGRVYKAVNRASIVTSTNGTTVPAGHEVAIKKFKPDKEGEQISYTGISQSAIREMSLCSELNHANVIRLIEIILEDKCIFMVFDYAEHDLLQIIHHHTQQPRHPIPPATVKSIMFQLLNGCHYLHTNWVLHRDLKPANIMVSSSGGVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDMWAIGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMMKIMEIMGAPTKDKWPLLTSMPEYQQLTALQTSMAAHQGRHAHGVPLASNLEKWYHNTISNAPSSTNTSSGASTSLSSLGQEGYRLLSGLLEYDPVRRLTAAQALQLPFFSTGDKVTANAFEGLKVDYPHRRVSQDDNDIRTSSQPGTKRSGLGDDSLLRPLKRVKD
Length481
PositionKinase
OrganismCordyceps militaris (strain CM01) (Caterpillar fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Cordycipitaceae> Cordyceps.
Aromaticity0.08
Grand average of hydropathy-0.392
Instability index47.16
Isoelectric point9.40
Molecular weight53566.51
Publications
PubMed=22112802

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28088
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.60|      17|      19|      17|      35|       1
---------------------------------------------------------------------------
   18-   34 (33.05/17.01)	PQPQNPQLQLRSGNT.QW
   36-   53 (26.55/11.75)	PSAAAPPMAFTSSSSlSW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     222.69|      68|      71|     326|     396|       2
---------------------------------------------------------------------------
  329-  396 (117.41/74.60)	WPLLTSMPEYQQLTALQTSMAAHQGRHAHGVPLASN....LEKWY.HNTISNAPSSTNTSSGASTSLSSLGQE
  398-  470 (105.28/59.66)	YRLLSGLLEYDPVRRLTAAQALQLPFFSTGDKVTANafegLKVDYpHRRVSQDDNDIRTSSQPGTKRSGLGDD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28088 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DYPHRRVSQDDNDIRTSSQPGTKRSGLGDDSLLRP
2) MPLRLRPSAGHESHQQQPQPQNPQLQLRSGNTQWNPSAAAP
441
1
475
41










Molecular Recognition Features






MoRF SequenceStartStop




1) LGDDSLLRPLKRVKD
2) MPLRLR
467
1
481
6