<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28051

Description Solute carrier family 13 member 5
SequenceMASVKTYLTKFKSFMILFLSPILLLPLIILVPNKIVRCAYVVILMAIYWCTDVIPVAVTSLLPVLLFPLFKILDSKEVCIQYMKDTNMLFLGSLIVAVAVERWQLHKRIALRMLLYVGTKPSMLMLGFMFITAFLSMWISNTATTAMMIPIVEAMLQQMVATNAAVDVCQGTLELSDKNKAGEFPGNQVIFEDLAAQKHEDEDTKNMYKAMNLCVCYAASIGGTATLTGTGPNVVGLGQMQELFPDSKDTINFASWFGFAFPNMVLMLVLSWLWLQSFYMRSKFKKSCTCCGLKRRSNEKVIYKVLQEEYKKLGPLTYAEINVLLCFALLIILWFSRDPGFMPGWLSIAWIDGKTNYITDATVSIFVSILLFIVPSQKPKFNFSSQTEEAENITKSSPSKRFHDYRKFLATVQASGLSEWLAKQMEPLSSVQPVIITLVSSCIVAITTECTSNVATTTLFLPVFASMSRSIGIHPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLKIIDMVKSGFIMNFIGIANDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQNNTTGK
Length648
PositionMiddle
OrganismCricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Myomorpha> Muroidea> Cricetidae> Cricetinae> Cricetulus.
Aromaticity0.12
Grand average of hydropathy0.284
Instability index42.68
Isoelectric point8.95
Molecular weight73661.35
Publications
PubMed=21804562

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
transmembrane transporter activity	GO:0022857	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
sodium ion transport	GO:0006814	IEA:UniProtKB-KW

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28051
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.57|      16|      33|      88|     103|       2
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   88-  103 (27.57/17.03)	MLFLGSLIVAVAVERW
  123-  138 (31.01/20.05)	MLMLGFMFITAFLSMW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.31|      22|      39|      19|      40|       3
---------------------------------------------------------------------------
   19-   40 (38.90/26.12)	LSPILLLPLIILVPNKIVRCAY
   61-   82 (39.41/26.56)	LLPVLLFPLFKILDSKEVCIQY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.06|      14|      33|     450|     463|       5
---------------------------------------------------------------------------
  140-  151 (17.37/ 7.92)	..SNTATTAMMIPI
  450-  463 (26.32/15.67)	CTSNVATTTLFLPV
  482-  494 (24.37/13.98)	CTMS.ASLAFMLPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.43|      28|      39|     312|     341|       7
---------------------------------------------------------------------------
  312-  341 (44.06/38.72)	KLGPLTYAEINVLLCFALLIIlwFSRDPGF
  354-  381 (47.36/32.87)	KTNYITDATVSIFVSILLFIV..PSQKPKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.22|      19|      21|     598|     618|      10
---------------------------------------------------------------------------
  598-  618 (29.25/25.91)	YEHFRKELVNAQCAkfIDEQQ
  622-  640 (34.98/23.31)	WQHYSRKRMRLQQA..LAEQQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28051 with Med31 domain of Kingdom Metazoa

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