<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28051

Description Solute carrier family 13 member 5
SequenceMASVKTYLTKFKSFMILFLSPILLLPLIILVPNKIVRCAYVVILMAIYWCTDVIPVAVTSLLPVLLFPLFKILDSKEVCIQYMKDTNMLFLGSLIVAVAVERWQLHKRIALRMLLYVGTKPSMLMLGFMFITAFLSMWISNTATTAMMIPIVEAMLQQMVATNAAVDVCQGTLELSDKNKAGEFPGNQVIFEDLAAQKHEDEDTKNMYKAMNLCVCYAASIGGTATLTGTGPNVVGLGQMQELFPDSKDTINFASWFGFAFPNMVLMLVLSWLWLQSFYMRSKFKKSCTCCGLKRRSNEKVIYKVLQEEYKKLGPLTYAEINVLLCFALLIILWFSRDPGFMPGWLSIAWIDGKTNYITDATVSIFVSILLFIVPSQKPKFNFSSQTEEAENITKSSPSKRFHDYRKFLATVQASGLSEWLAKQMEPLSSVQPVIITLVSSCIVAITTECTSNVATTTLFLPVFASMSRSIGIHPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLKIIDMVKSGFIMNFIGIANDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKEPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQNNTTGK
Length648
PositionMiddle
OrganismCricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Rodentia> Myomorpha> Muroidea> Cricetidae> Cricetinae> Cricetulus.
Aromaticity0.12
Grand average of hydropathy0.284
Instability index42.68
Isoelectric point8.95
Molecular weight73661.35
Publications
PubMed=21804562

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
transmembrane transporter activity	GO:0022857	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
sodium ion transport	GO:0006814	IEA:UniProtKB-KW

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP28051
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.57|      16|      33|      88|     103|       2
---------------------------------------------------------------------------
   88-  103 (27.57/17.03)	MLFLGSLIVAVAVERW
  123-  138 (31.01/20.05)	MLMLGFMFITAFLSMW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.31|      22|      39|      19|      40|       3
---------------------------------------------------------------------------
   19-   40 (38.90/26.12)	LSPILLLPLIILVPNKIVRCAY
   61-   82 (39.41/26.56)	LLPVLLFPLFKILDSKEVCIQY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      68.06|      14|      33|     450|     463|       5
---------------------------------------------------------------------------
  140-  151 (17.37/ 7.92)	..SNTATTAMMIPI
  450-  463 (26.32/15.67)	CTSNVATTTLFLPV
  482-  494 (24.37/13.98)	CTMS.ASLAFMLPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.43|      28|      39|     312|     341|       7
---------------------------------------------------------------------------
  312-  341 (44.06/38.72)	KLGPLTYAEINVLLCFALLIIlwFSRDPGF
  354-  381 (47.36/32.87)	KTNYITDATVSIFVSILLFIV..PSQKPKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.22|      19|      21|     598|     618|      10
---------------------------------------------------------------------------
  598-  618 (29.25/25.91)	YEHFRKELVNAQCAkfIDEQQ
  622-  640 (34.98/23.31)	WQHYSRKRMRLQQA..LAEQQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP28051 with Med31 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
NANANA

Molecular Recognition Features

MoRF SequenceStartStop
NANANA