Description | Mediator of RNA polymerase II transcription subunit 19 |
Sequence | MGDSSANGNVYLIDRKKVYEPVKPSPLDNLIKVYGLEETARSLARTNPDGSKGVKLRKSYKNHIQDLPGKHNIPKAKPVPNGLLDPMLSQFPNIIKPIESKLVNKALEFDKTPLNGIPGFNTADLGISDQQTLMRRDDGSEMDEDKRKRKKKQMNGDTPKRIHI |
Length | 164 |
Position | Head |
Organism | Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 / NRRL Y-1498 / VKM Y-70) (Yeast) (Yamadazyma tenuis) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Yamadazyma. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.884 |
Instability index | 44.59 |
Isoelectric point | 9.67 |
Molecular weight | 18385.92 |
Publications | PubMed=21788494 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364151 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP28028 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) ANGNVYLIDRKKVYEPVK 2) LDNLIKVYGLEET 3) VKLRKSYKNHIQDLPGKHNIP | 6 27 54 | 23 39 74 |
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