<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28025

Description Uncharacterized protein
SequenceMSKARSRNSLLLSHSKVAHSLNGTDELSLMKYHLDKPIDSIYPLDSNNSNKDEVKLKHKKGRELTYPDFHPWKDHTQMDDESSRVEIDKMTNSLYLNKGLFEAPQVPNEYYTARNLIQATLFSSGENCFEVLKELSQHLAGVHKTRNEVINKIRADSNNFKLPAKVTLTTLKREAWLADLANDSVPLSKISSRIPHGLKNKVLVDVLCSNSVPIPRAIWFTKCVLYGDAVAIRKKMQNRGESDALESQWLQEWTHQVVDYMYRFSRDFSMVSTPEKKSDIMNKLNYLLKYVQTLYIECLIDKSTLLSSIVRFLKDGLNLEPHYIVQLLLESSKSEANDEEFGTHRDAEINFGQRFLALLLLQVFWIDITKLDYLCKDLSEALLLNYYFISRVPISTSKQSRIPGTLERSLSLKLKESVLGSISDSIRYMFKLNTNAFIIPNYWILIGSTLYQVILGESELMSNQEIEDIQKQLQLIQHRNESLMLNMKHSKSTKEEKPFINSHRRTSSFPAGFTPLNLPFETNVVSPEQKYEELDTLESELFINRSSDDIFRIIDYLDKLKFNEELAKLLRPSLKQKSGNTDWKLNLSVAITWCITIHREPGYSSENILMFCGFLKHRVLAAGSLKYITKIKASIENSILDTIYDLLAGQPQSINFQNLYVLINELYQLKVISISAYLRKLIASGMFFSEPGVELQLNNPSVKMHVNILQNLPVLNNKQCDSILKKWSDPQINFTHKFEHGQSVLKQEVIDKFANNTLVSCNLQNLENLEVGVKYLLVNWMTEEIKKIINSSSKLIHIRFLTVTLLYKVYSSCDNLAVFFKVLVKSVLRNDGKVIVLDMDSLYLIAKLMVRHFKLIKTISGSDTGSVGYEIFRLIMVNYKDLATREPSYLNFKSIWDFIETSFDTKSRSDINADPQLQKPATIPQFIYSKATVDSPMKLNAHTVENRKASTEYSIDEFSSDLNDLTNKSYVFMTTSEVNYAFSALKLGENNETYNGENGSKRFAIVLFDYYMKYGGRLSKEEENLLIRLLINTKHILQAQFFFPFIDCFAYFTQKQIPKFENEQEKLKFTIVAKKLIANEILEIQEVLTIITTIFSNQEMVYNYNSMLHDLVIGDNIQEEQVLTEGQILPLQISRIAFYSKQGAKTLEIIANEIKAQSMEVLSFSISYNQNLEQLFTKWIVTRSRFFMENIKVNFDDDQIISLINRVSGLNTNIHSLDDLLINSSKINEFNLPLFQILFRLILTREMIKISDIERFNQLKMFIETMIPQLRFQFSLDNSFFGELFNSLPSDFKSDVLTILSSILFSHIRLLEDKFKAECEFNGVDILPLLADFFKKFSFSSIESIETTTLVLGGLSDYLSNLLTLLDSMSTPKKQAENESIDRSLSVFIRILIIYKESIAKFILNHDQGFNFLVNLKRLLVSEYFTGCNEKLKILLYDLMLISKNLLAQELNLERGKRNDIKDVIVDTPTNNNAGTPSISGQPSNLTPNQEKSNVFLSQDLVANGQLSKFEKFAAIFDLPDIDNHDILQKYLDDTNIISAVTLQENEINASGDFHIFNNSGLYLVKSSRDSMFSNEPFNLLGEKKKVGDPPKFKISSFEILENTNPEINNGKINLSLFDAYITKQNPP
Length1628
PositionKinase
OrganismCandida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 / NRRL Y-1498 / VKM Y-70) (Yeast) (Yamadazyma tenuis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Yamadazyma.
Aromaticity0.10
Grand average of hydropathy-0.198
Instability index39.11
Isoelectric point6.23
Molecular weight187013.62
Publications
PubMed=21788494

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28025
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.45|      25|      85|     449|     483|       1
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  449-  483 (31.08/41.66)	TLyqvilgESELMSNQEIEDIQK......QLQLiqhrNESL
  536-  566 (37.37/21.78)	TL......ESELFINRSSDDIFRiidyldKLKF....NEEL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.90|      50|      85|    1472|    1527|       2
---------------------------------------------------------------------------
 1472- 1527 (76.36/51.99)	NNAGTPSISGQPSNLTPNqEKSNVFLSQDLVANGQlskfeKF.AAIFDL.....PDIDNHDI
 1558- 1613 (76.54/39.46)	NNSGLYLVKSSRDSMFSN.EPFNLLGEKKKVGDPP.....KFkISSFEIlentnPEINNGKI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     345.00|      96|     414|     778|     903|       3
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  354-  446 (109.83/58.38)	RFLALLLLQVFWIDITKLDYLCKDLSEALLLN...........YYFISRvpISTSkqsripgtlerslSLKLKESVLGSISDSIRY.MFKL...NTNAFII..PNY......WILI.
  603-  664 (86.46/40.21)	...........YSS.ENILMFCGFL.........KHRVLAAGSLKYITK..IKAS............iENSILDTIY....................DLLAGQPQSINFQNLYVLIN
  799-  900 (148.71/102.86)	RFLTVTLLYKVYSSCDNLAVFFKVLVKSVLRNdgKVIVLDMDSLYLIAK..LMVR.............HFKLIKTISGSDTGSVGYeIFRLimvNYKDLATREPSYLNFKSIWDFIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.80|      27|     209|     920|     980|       4
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  953-  980 (43.34/68.59)	YSIdEFSSDLNDLTNK.....SYVFMTTSEVNY
 1164- 1195 (42.46/ 9.89)	FSI.SYNQNLEQLFTKwivtrSRFFMENIKVNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     145.40|      45|      52|    1250|    1301|       5
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 1225- 1248 (23.39/ 8.30)	.SKINEFN.LPLF......QILFRLILTREMI................................
 1250- 1300 (72.82/58.26)	ISDIERFNQLKMFietmipQLRFQFSLDNSFFGEL.FNSLPS............DFKSDVLTIL
 1317- 1366 (49.19/24.00)	A.ECE.FNGVDIL............PLLADFFKKFsFSSIESietttlvlgglsDYLSNLLTLL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.31|      29|     449|     275|     333|       6
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  301-  331 (44.26/66.81)	DKSTLLSSIVRFlkDGLNLEPHYIVQLLLES
 1196- 1224 (49.04/13.80)	DDDQIISLINRV..SGLNTNIHSLDDLLINS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.75|      16|      72|    1073|    1088|       7
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 1073- 1088 (27.12/15.61)	AKKL..IANEI.LEIQEVL
 1144- 1162 (18.63/ 8.65)	AKTLeiIANEIkAQSMEVL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.87|      24|      25|     163|     187|       8
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  163-  187 (35.15/34.04)	PAKVTlTTLKREAWLADLANDSVPL
  191-  214 (39.72/32.90)	SSRIP.HGLKNKVLVDVLCSNSVPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.82|      37|      52|      25|      64|      12
---------------------------------------------------------------------------
   25-   64 (53.35/46.89)	DELSlmKYHLDKPIDSIYpLDSNNSNKDEVKLKHKKGREL
   80-  116 (63.46/42.49)	DESS..RVEIDKMTNSLY.LNKGLFEAPQVPNEYYTARNL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28025 with Med12 domain of Kingdom Fungi
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