<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28008

Description Uncharacterized protein
SequenceMSNWQSPNIMSMMQPVNKNIGVTLEDRQKVIQVVLATFTRTNFPGDPPRLAKSACDFEGWIMNRAANKEEYGKLVHMKLEQIKQKFQNQQQQQQQQQQLQFMQQQAQARAQPQQQAQVQARQQQQQQLRDMPNMNQQQVPPQIQQQQQNQQQQPPQQQHQTIDQLVRSTPIPQVVLAKLPNLPPGITRWQQIMELIQKKKMPEAYLPIIKDMYSAHTQLVLHDQQKMNQMQRNVTNDSNNTISSSPPTMNPTNTTSTTTNNNNNNMMMNTYASAGLNNLTPQQREQLMQRQLNKRNMQQQQMQQQQQQHQPPMQQQQSPQLMQQIPDSASVPPIPQQQQPPQQQIKQPQIQITQQDYANYSAKALKMLQEIEARGQLNQPLTPAMKESFVRRFIIRQKQNLLQQQQQQQQQQQQQQAQNQQHPQQIAQQQHPSVPLQQPQPMQPMLQQGQPQQSQQQSPMLTNIKTPMMKPNQQTPMSNTLSSPLMPQQRGPTAPVGPTPVQSAPTSGIAPLTEEAKLQLKQLFTEVASKEVMLKDVTNMLTPEQKERVRTLLNEIQIQFPNIDAVISYVYVLTRNIEVTKRLIQMKFTIKKILDNLRSGIYITNPEMLTKLSMQLAKYFGYVRDQVALRKQQQGQRAQVQAQAQQQQQQAQAQQRQVPPQQTPLMQNQMNVQQQQQQQQQQPGQFMGQNQQIPPQQQVNMGNSNSWNGAGGPGASGPVKTFPMQGAVPRQNISGSPLMPQVPVPMQMPVSVPQQTIPQPPPSGVPMSQQQQQQQQQQQIPTPQQMAGQPLAKARQPSKVGLAAAAAAAAAASQASTPAAAKKTVGGQGRKKKQSISAAPTPAAASSGSTAPMTAPTPTPGSLANAIKTPNYNIATPQIPQSQSNKNTPAGQSPNVRATTNNTVSTPVIVDASVDLFAMIQSDPKVARRKELSNSDPVKFFYASLANLLELDENIVDGSAKKGRSPLSPVMTTLTSANGKGWTCEIKPQAITGSFRQVGLIRELVDDDDIIGRCEELALGEVGVKREFESEDLDMLFTDKKPRLDDHIKEESNGGLMDDYKYVYEPVGFDEWKDFIISSIQ
Length1081
PositionTail
OrganismSpathaspora passalidarum (strain NRRL Y-27907 / 11-Y1)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Spathaspora.
Aromaticity0.04
Grand average of hydropathy-0.840
Instability index69.23
Isoelectric point9.70
Molecular weight121302.28
Publications
PubMed=21788494

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP28008
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     827.67|      91|      99|     266|     356|       2
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   33-  123 (80.77/12.88)	VVLATF.....................TR....T...N.F..P..GDPPRLaksacdfegwiMNRAA..NKEEygklvhMKL..................................EQI...KQKfqnQQQQ.Q....QQQQQLQFMQQ....................Q....A.QARAQ..........PQ...QQ...AQVQARQQ.
  165-  262 (85.91/14.24)	LVRSTP.....................IPqvvlAKLPN.L.PPgiTRWQQI...........ME.LI..QKKK......MPE..................................AYLpiiKDM...YSAHtQL.VLHDQQKMNQMQRNV...............TNDSNNTI...SSSP..........PT...MNPTNTTSTTTNNN
  266-  356 (171.27/36.82)	MMMNTY.....................AS....AGLNN.L.TP..QQREQL...........MQRQL..NKRN......MQQ..................................QQM...QQQ...QQQH.QP.PMQQQQSPQLMQQIP...............DSASVPPIP.QQQQP..........PQ...QQIKQPQIQITQQD
  367-  458 (113.74/21.60)	MLQEIE.....................AR....GQLNQpL.TP..AMKESF...........VRRFIirQKQN......LLQ..................................QQQ...QQQ...QQQQ.QQ.QAQNQQHPQ...QIA...............QQQH.PSVPlQQPQP..........MQpmlQQ.GQPQ.QSQQQS
  459-  531 (67.38/ 9.34)	PM.................................LTN.IkTP.......M...........M.......KPN.......QQ..................................TPM...SNT...LS...SP.LMPQQRGP.......................TAPVGPTP.VQSAPtsgiaplteeAK...LQLKQLFTEVASKE
  532-  646 (71.22/10.35)	VMLKDV.....................T........NM.L.TP..EQKERV............RTLL..NEIQ......IQFpnidavisyvyvltrnievtkrliqmkftikkilDNL...RSG...IYIT.NP.EMLTKLSMQLAKYFG...............YVRDQVALR.KQQQG..................QRAQVQAQAQQ
  647-  710 (89.07/15.07)	Q............................................QQQAQA...........QQRQVppQQTP......LMQ..................................NQM...NVQ...QQQQ.Q....QQQQPGQFMGQ...........................NQQIP..........PQ...QQVNMGNSNSWNGA
  717-  842 (89.70/15.24)	GPVKTFpmqgavprqnisgsplmpqvpVP....MQMPV.S.VP..QQ..TI...........PQPPP..SGVP......MSQ..................................QQQ...QQQ...QQQQ.IPtPQQMAGQPLAKARQPskvglaaaaaaaaaaSQASTPAAA.KKTVG..........GQ...GRKKKQSISAAPTP
  853-  909 (58.62/ 7.02)	MTAPTP.....................TP....GSLAN.A.I.......................KT..PNYN......IAT..................................PQI...PQS...QSNK.NT.P..AGQSPNVRATTN...............NTVSTPVI....................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.31|      28|      29|     919|     947|       3
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  919-  947 (43.53/36.06)	MIQSDPKV...ARRKELSNSDPVKFFYASlAN
  948-  978 (39.78/27.30)	LLELDENIvdgSAKKGRSPLSPVMTTLTS.AN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.33|      16|      22|     124|     139|       4
---------------------------------------------------------------------------
  124-  139 (29.24/ 9.30)	QQQQLRDMPNMNQQQV
  147-  162 (30.10/ 9.85)	QQNQQQQPPQQQHQTI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.99|      22|     551|       7|      32|       5
---------------------------------------------------------------------------
    7-   32 (35.52/34.25)	PNI...MSMMQPVNKNIGVTledrQKVIQ
  561-  585 (33.47/21.50)	PNIdavISYVYVLTRNIEVT....KRLIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.77|      15|      22|     997|    1011|       6
---------------------------------------------------------------------------
  997- 1011 (25.24/20.76)	QVGLIRELVDDD.DII
 1021- 1036 (21.53/16.63)	EVGVKREFESEDlDML
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP28008 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DMYSAHTQLVLHDQQKMNQMQRNVTNDSNNTISSSPPTMNPTNTTSTTTNNNNNNMMMNTYASAGLNNLTPQQREQLMQRQLNKRNMQQQQMQQQQQQHQPPMQQQQSPQLMQQIPDSASVPPIPQQQQPPQQQIKQPQIQITQQDYAN
2) IKQKFQNQQQQQQQQQQLQFMQQQAQARAQPQQQAQVQARQQQQQQLRDMPNMNQQQVPPQIQQQQQNQQQQPPQQQHQTIDQLVRSTP
3) QGQRAQVQAQAQQQQQQAQAQQRQVPPQQTPLMQNQMNVQQQQQQQQQQPGQFMGQNQQIPPQQQVNMGNSNSWNGAGGPGASGPVKTFPMQGAVPRQNISGSPLMPQVPVPMQMPVSVPQQTIPQPPPSGVPMSQQQQQQQQQQQIPTPQQMAGQPLAKARQPSKVGLAAAAAAAAAASQASTPAAAKKTVGGQGRKKKQSISAAPTPAAASSGSTAPMTAPTPTPGSLANAIKTPNYNIATPQIPQSQSNKNTPAGQSPNVRATTNNTV
4) SAKALKMLQEIEARGQLNQPLTPAMKESFVRRFIIRQKQNLLQQQQQQQQQQQQQQAQNQQHPQQIAQQQHPSVPLQQPQPMQPMLQQGQPQQSQQQSPMLTNIKTPMMKPNQQTPMSNTLSSPLMPQQRGPTAPVGPTPVQSAPTSGIAPL
211
82
634
361
359
170
904
512










Molecular Recognition Features






MoRF SequenceStartStop




1) AAAKK
2) GLAAAAAAAAAA
3) QGRKKKQSIS
4) RRFII
819
801
828
391
823
812
837
395