<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP28007
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MSNTNEDLISSLYPPPPPYVKFFTNENLAKLAQWEQQRKSEPSENTVEVPPGELRFLVPPAPPSGSHYRGYGNIWSFEDKLPSLKSTNWRQLYPAENDESITSETKIKELHKLMDSLLLNFLELIGIMSIDPTNYESKVKDISLILININHLLNTYRPHQTRESLIMLLRKQIDLKRQEIDTIEKVSEEVKTKIKKLTEFEINSKEEHFKRNNKNDEQIRKLKSEIIEKLLSDI |
Length | 234 |
Position | Middle |
Organism | Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes>
Saccharomycetales> Debaryomycetaceae> Spathaspora.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.701 |
Instability index | 51.81 |
Isoelectric point | 6.04 |
Molecular weight | 27345.91 |
Publications | PubMed=21788494
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP28007
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 145.25| 40| 42| 12| 53| 1
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12- 53 (69.30/56.93) LYPPPPPYVKFFtnENLAKLAQWEQQRKSEPSENTVEVPPGE
57- 96 (75.96/55.47) LVPPAPPSGSHY..RGYGNIWSFEDKLPSLKSTNWRQLYPAE
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