<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27994

Description Uncharacterized protein
SequenceMSKPRSRNSLLSSHNRTSYSNSTKDELLAMKYQMDKPALPLYPLSDLNTNSSSDTDSSKRDHEEHETTYPDFKPWKDHTQLAGDKQEQEIQKMSNTSFLNKGYFEAPQVSNEYYSARNLIQATVFSSTDNCNYVLRELSQHLANAYKTRNEVINKIKYDSNNFRIPPRVTLTATKKEAWLKDLGNSNIPIMKIGEKIPHGIRNKVLIDSVCSRNVPLNRALWFTKCVLFSELLALRRKHQARLSVSGPIPGSEFNTVEKFEIHWLQEWTQQVCDYILKFSREMVHITTPEKKEHYMNKLTYLLTYVQSLYVECLVDKTFFLSVIFKSLKDGLPLEVKHINELVFTSNDDEKLTETWIDEIDLNYGQRLVSLTLIKIFWKDILKTDYLCKELSELLLLNHLFINRISSLESHSYHHKFALPETLAQNVLEMISNTVIYLFKYNTNVFIIPKYWILLQDPLVKIMVEHGESQLENEQDEIKNQLELIKYRNESLILNLKHVAEHKQPKVRARSNSFSNMTPIENDINTFMNRDTNDILRILCCLDRVKLNNDLASLLKPTTHGIRKTGCPNWRINLRLVLFWCITPYRSHKNSSEGILIVCNFLKKHILQSLHGSIRTEFETELLEIIYQIAESYESLFVKYNLYVLINELYQLKVLTIASYLRKLIASGIFFLAPGTTEDLSNLPPVVKIHLDILQSLPVLNNRQCDSILKKWTPEGFNFKDKFDRGQQILQTEIIDRLVNNTFNVNIESNWNYIKSLNVGLKFLLVNWITNVLKTTLNDSPKLIHFDPVVIANLYMFYSNCDNLTVFFKVLVKTILRNEGGMIIFYLDSLYFIAKLVIHHFKLIKSLAGSNDLSSTGYELFKLIVTTYKDLSQREYNYFSFNQVWNFIDDVIEKEYHEKAKRSKVLENQLFSKDTMDTPMNINTVDVHSKSSSSSDRYTSADFRNDLETLRNSRVQALDPSEVQDTLDTLNLEISELSLSEAVTAQLEYLFKQGISQDQENLIIKLLFNARISLKEDGSFNELVRQFVMNVMQSEADFNIKANFLKKLVISEIFKMNDLVSFCQTESQAGPLVMDVIIGNEGEAANLAPNESLGLSIHRVTFREKSMANFISILSKELLKGSIFHSDLMAKHKESMLKYIHDALIIHPKLLFEELFVKLSKEDCIDLLNLLLGREHTTFIRQLSDFEILTPDINEFNLPIVQMLIKIISYYELNNSDDIRQKLELLLGTLISKCEFKFSASNSFFGELFSFISWEHKIFILDIIETEFLTNTKFEETISLDNGRDLLPPFSDFFNKFSLSSANTVDCSPVFFTNLCEFLTKLTKAVNTPHLFTDSLSTSILIFLRILIIHNSALCKLISIGQETHVLFIQNLLAILHSQFLGSHEKLRILLYDLLLLMKSSVTQELTNAMEPDHEGTSPGFSSSAPSDDSKKNGSVPIVPSMSIQRVFELPDEPKDDNPFKDNIDESLVQCALMLDDEELNHGGDVHAFNDSGLVLLQARPHSVSLPFGILNNNEKVSNEIKMVKFRSFEILEDTSSALNDGCVNLQLLDAYTTRENPP
Length1559
PositionKinase
OrganismSpathaspora passalidarum (strain NRRL Y-27907 / 11-Y1)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Spathaspora.
Aromaticity0.10
Grand average of hydropathy-0.190
Instability index36.20
Isoelectric point5.84
Molecular weight179563.91
Publications
PubMed=21788494

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27994
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.63|      19|      21|     356|     374|       2
---------------------------------------------------------------------------
  356-  374 (32.94/18.26)	WIDEIDLNY.GQRLVSLTLI
  378-  397 (28.68/15.00)	WKDILKTDYlCKELSELLLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.22|      25|      25|     521|     545|       3
---------------------------------------------------------------------------
  521-  545 (44.45/26.26)	ENDINTFMNRDTNDILRILCCLDRV
  548-  572 (45.77/27.24)	NNDLASLLKPTTHGIRKTGCPNWRI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.20|      18|      18|    1297|    1314|       5
---------------------------------------------------------------------------
 1278- 1293 (21.68/13.13)	..ISLDNGRDLLPPFSDF
 1297- 1314 (31.54/23.44)	FSLSSANTVDCSPVFFTN
 1318- 1334 (26.98/18.68)	FLTKLTKAVN.TPHLFTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.20|      15|      17|     947|     963|       6
---------------------------------------------------------------------------
  947-  962 (21.14/21.95)	LETLrNSRVQALDPSE
  967-  981 (24.06/12.01)	LDTL.NLEISELSLSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.95|      23|     363|     879|     911|       7
---------------------------------------------------------------------------
  879-  911 (33.06/36.79)	FSFNQvWN...FIDDVIEKEYhekakrskvLENQLF
 1249- 1274 (37.89/19.79)	FSFIS.WEhkiFILDIIETEF.........LTNTKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.63|      17|     384|     423|     450|      12
---------------------------------------------------------------------------
  150-  166 (32.18/10.83)	NEVINKIKYDSNNFRIP
  433-  449 (32.44/12.51)	NTVIYLFKYNTNVFIIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     290.09|      93|     423|     250|     352|      13
---------------------------------------------------------------------------
  250-  352 (151.55/117.39)	PG.....SEFNTVEKFEIHWLQE...WTQQVCDYILKfsremvhITTPEkKEHYMNKLTYLLTYVQSLYVECLVDKTFFLSV.....ifKSLKDGLP.LEVKHI.NELVFTSNDDEKL
  674-  783 (138.54/85.04)	PGttedlSNLPPVVKIHLDILQSlpvLNNRQCDSILK.......KWTPE.GFNFKDKFDRGQQILQTEIIDRLVNNTFNVNIesnwnyiKSLNVGLKfLLVNWItNVLKTTLNDSPKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.59|      15|      24|    1338|    1358|      14
---------------------------------------------------------------------------
 1338- 1352 (24.49/21.59)	TSILIFLRILIIHNS
 1364- 1378 (25.10/ 7.96)	THVLFIQNLLAILHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.08|      18|     236|    1199|    1218|      15
---------------------------------------------------------------------------
 1199- 1216 (28.97/20.86)	PIVQMLIKIISYYELNNS
 1222- 1239 (27.11/11.43)	KLELLLGTLISKCEFKFS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27994 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSKPRSRNSLLSSHNRTSYSNSTKDELLAM
2) PLYPLSDLNTNSSSDTDSSKRDHEEHETTYPDFKPWKDHTQLAGDKQEQEIQK
1
40
30
92










Molecular Recognition Features






MoRF SequenceStartStop




1) TKDELLAMKYQMDKPALPLYPLSDL
23
47