<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27989

Description Uncharacterized protein
SequenceMEGTQQTTAALIATRTNSIIRQTRLEINMSRDHDLWNSSRGEAIGTAPGNSVETSDSTRINEDAVIDSSAPSRPGLTSRAISSDFIGTDEGNVASFLAPPGSEHMSGAPASNPTSHPARINDSSVTDLLNSTVPEYNSRVPSSDFVVNHWPVSESSMVQSIEAVATEPISSIPGPEAVTPYSSSHQLEMMPLQPIDALTYGFDLPPHPIESTGEIIINSSLLNEVAAEEPLGFVEPAFESITLHQGIASLGLPNEVTAASGLILDNGMLRQEGSSAQMIQNDLHMKDSLDFENISIPDLLNEVTATAKPISNSGTLGQEDPYAQVVQNDVSLENLLGDGNDSRLSFLDAFAANQFTEFPDLVFDNGMLHQDEPPPNFPHEVTAITEPVPNKKAASITGLIASNEVTAVTEPVAEDGRPSRNDLIHKHEPVAEDERPSRNDRVHKHEPVHNDDLADGPAVLRASKADKLTDRQERAIAALLIRFQNLVKLAALPTEDAFTKETAAAEGLRMEVESNALTSAAEDLLKLTRELKEFWIFGSLRGIGEGEGDGEMETDSKKVAELIEKQLEKKHEQEKNKA
Length578
PositionHead
OrganismBotryotinia fuckeliana (strain T4) (Noble rot fungus) (Botrytis cinerea)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Sclerotiniaceae> Botrytis.
Aromaticity0.04
Grand average of hydropathy-0.426
Instability index47.33
Isoelectric point4.53
Molecular weight62428.36
Publications
PubMed=21876677

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27989
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.28|      14|      15|     415|     429|       1
---------------------------------------------------------------------------
  415-  428 (27.77/13.52)	DGRPSRNDLIHKHE
  433-  446 (25.51/13.42)	DERPSRNDRVHKHE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     259.88|      71|      76|     169|     243|       2
---------------------------------------------------------------------------
  100-  168 (42.66/15.47)	...PGSEHMSgaPASnpTSHPAR..INDSSVTDLLNstvpeYNSRVPSsdfvvnhWPVS........ESSMVQsiEAVATEP.............
  170-  243 (122.93/62.13)	SSIPGPEAVT..PYS..SSHQLE..MMPLQPIDALT.....YGFDLPP.......HPIESTG.EIIINSSLLN..EVAAEEPlgfVEPAFESITL
  248-  316 (94.29/44.31)	ASLGLPNEVT..A.A..SGLILDngMLRQEGSSAQM.....IQNDL.........HMKDSLDfENISIPDLLN..EVTAT.....AKPISNSGTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.44|      11|      23|     380|     390|       3
---------------------------------------------------------------------------
  380-  390 (21.45/14.76)	EVTAITEPVPN
  404-  414 (19.99/13.22)	EVTAVTEPVAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.95|      24|      25|      48|      71|       4
---------------------------------------------------------------------------
   48-   71 (40.83/18.29)	PGNSVE..TSDSTRINEDAVIDSSAP
   74-   99 (37.12/16.13)	PGLTSRaiSSDFIGTDEGNVASFLAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27989 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DEGNVASFLAPPGSEHMSGAPASNPTSHPARINDSSVTDLLNSTVP
2) EVTAVTEPVAEDGRPSRNDLIHKHEPVAEDERPSRNDRVHKHEPVHNDDLADGPAVLRASKADK
3) GEGDGEMETDSKKVAELIEKQLEKKHEQEKNKA
4) RQTRLEINMSRDHDLWNSSRGEAIGTAPGNSVETSDSTRINEDAVIDSSAPSRP
89
404
546
21
134
467
578
74










Molecular Recognition Features






MoRF SequenceStartStop




1) METDSKKVAELIEKQLEKKHEQEKNKA
552
578