<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27941

Description Uncharacterized protein
SequenceMENRHAPPSATQRPYGYAKPYGGAHPARAPNSSGLMHQDASAAAPFSVFPLLPDVAMSQAKRPRAEVSFQPRPYPADRGTGSMSYQSKVRVTDRYKVVGFISSGTYGRVYKALGRHGQGGEFAIKKFKPDKEGEQASYTGISQSAVREMALCSELNHQNIIRLIEIILEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPTTIKSIMFQLLNGCQYLHANWVLHRDLKPANIMVTSAGEVKIGDLGLARLSYKPLHSLYSGDKVVVTIWYRAPELLLGSRHYTPAIDLWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDILGLPTKERWPLLTSTTEYSQLATLQPPVSHGHHHQHHHHQQQQHHQAGAYQSSPRQPPGAGASQLEKWYYNTIGVGQQQQQQHTGSTGPGGGGGGGGGNPLATLGAEGYKLLAGLLEYDPEKRLTAAAALQHPFFSTGDPVSANCFEGLKTEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLARPVKRVKE
Length524
PositionKinase
OrganismThielavia terrestris (strain ATCC 38088 / NRRL 8126) (Acremonium alabamense)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Sordariales> Chaetomiaceae> Thermothielavioides> Thermothielavioides terrestris.
Aromaticity0.08
Grand average of hydropathy-0.530
Instability index45.77
Isoelectric point9.26
Molecular weight57922.97
Publications
PubMed=21964414

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27941
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.87|      22|      36|     370|     393|       1
---------------------------------------------------------------------------
  370-  393 (39.65/24.69)	HHQQQQHHQAGAyqSSPRQPPGAG
  407-  428 (41.22/19.67)	VGQQQQQQHTGS..TGPGGGGGGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     335.19|     109|     172|      77|     194|       2
---------------------------------------------------------------------------
   77-  194 (171.79/154.26)	DRGTGSMSYQ........SKVRVTDRYKVVGFIsSGtyGRVY.KALGRHGQGGEFA.IKKFKPDKEGEQASYTgiSQSAVRemalCSELNHQNIIRLIEIILEDKCIFM..VFEYAEHDLLQ..IIH.HHTQQ
  245-  368 (163.40/119.38)	DLGLARLSYKplhslysgDKVVVTIWYRAPELL.LG..SRHYtPAIDLWAVGCIFAeLLSLRPIFKGEEAKMD..SKKTVP....FQRNQMQKIVDILGLPTKERWPLLtsTTEYSQLATLQppVSHgHHHQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.59|      16|      38|     430|     450|       3
---------------------------------------------------------------------------
  430-  450 (23.54/22.82)	GNPLATLGAEGYKllaglLEY
  470-  485 (31.05/17.60)	GDPVSANCFEGLK.....TEY
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27941 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) ATLQPPVSHGHHHQHHHHQQQQHHQAGAYQSSPRQPPGAGASQ
2) CFEGLKTEYPHRRVSQDDNDIRTSSLPGTKRSGLPDDSLARPVKRVKE
3) NTIGVGQQQQQQHTGSTGPGGGGGGGGGNPLATL
354
477
403
396
524
436

Molecular Recognition Features

MoRF SequenceStartStop
1) EKWYY
2) SLARP
3) TQRPYGYAKPYG
398
514
11
402
518
22