<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27913

Description Uncharacterized protein
SequenceMASPTLPVEALDRMRIQLGLLSQSINSLLQELRTSDPLPPWTTLTAQLAILNSQLSTISRSLHQHSASLSTTVVFPLPTFPGRTQDGQLHRLLGKKLSPEVQDWIQIGRKAGLALTSKPKNDDDDSDDDSEPEAEDEQEADDDDDDEMDEDDGDDPDSKRRKRHWALKIVQKDQRSRDWDSDFTKEEIEAVGGDLTRIQTGLKTHLDGTIIKRSMDSSALSTSALNKRDENGWTLEMMFRFMSTGMRPVEDHPGVNDWMNPNVSTTMNTSAKKTTIPASATGARRNTGPNMTTSGGTNIVTGMTTNTGASVISEVTTSAETKMVTVTDVDAKPGIDTDTNISPQMNMVPESILITGKVTPAQTPTLAQTPTPARNFITSITLAPQPSFDVTKPPPTEQANQAPPTTKEGQYPDATAIEDPNLSSSSLPGLGSNQNITRAPPPEKFCQTPLTLEEEGKDLKATPSESRQFETEISNDSDDGSSVSDLRASMATPKPSSPASPASPASPAFNFPLVKFTVKSKKIATPDISSPNVSTPKTSASNLSSFEIITPDVSSTRDSISNISLLSDQSNASNITARLTRSKAKALAAAQAAVQASVQGTGEDVSIVDQLDCLLTSFPVRSATSNTISNDTTTTPPATIPSTLTKTKTTRSPKHPKSSKPPRAPRVSKKPKTTKKLGGTKPPNKPNQLEPLTSPSEVSLPADLDDLFKNMDDMEGLFGGV
Length721
PositionHead
OrganismArthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) (Nematode-trapping fungus) (Didymozoophaga oligospora)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Orbiliomycetes> Orbiliales> Orbiliaceae> Orbilia> Arthrobotrys oligospora.
Aromaticity0.03
Grand average of hydropathy-0.632
Instability index50.02
Isoelectric point5.03
Molecular weight77366.25
Publications
PubMed=21909256

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27913
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     113.59|      21|      22|     281|     301|       1
---------------------------------------------------------------------------
  281-  301 (38.24/22.58)	TGAR......RNTG....PNMTTSGGTNIVT
  305-  325 (21.07/ 8.63)	T..........NTGasviSEVTTSAETKMVT
  329-  355 (24.04/11.04)	VDAKpgidtdTNIS....PQMNMVPESILIT
  359-  378 (30.24/16.08)	TPAQ......TPT.....LAQTPTPARNFIT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.47|      23|      23|     522|     544|       2
---------------------------------------------------------------------------
  490-  514 (26.42/ 9.12)	.MATPKPSSPaSPASPASPAFNfpLV
  522-  544 (41.64/18.77)	KIATPDISSP.NVSTPKTSASN..LS
  547-  564 (30.41/11.65)	EIITPDVSS......TRDSISN..IS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.50|      27|      36|      17|      45|       4
---------------------------------------------------------------------------
   17-   43 (49.50/27.97)	QLGLL.......SQSINSLLQELRTSD..PLP..PWTT
   47-   84 (32.00/10.95)	QLAILnsqlstiSRSLHQHSASLSTTVvfPLPtfPGRT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.46|      15|      19|     648|     665|       5
---------------------------------------------------------------------------
  648-  665 (24.58/16.54)	KTTrspKHPKSSKPPRAP
  672-  686 (28.88/12.64)	KTT...KKLGGTKPPNKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.24|      18|      19|     383|     400|       6
---------------------------------------------------------------------------
  383-  400 (33.03/12.32)	APQPSFDVTKPPPT..EQAN
  402-  421 (26.21/ 8.47)	APPTTKEGQYPDATaiEDPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.40|      11|      19|     236|     246|       7
---------------------------------------------------------------------------
  236-  246 (21.89/15.01)	EMMFRFMSTGM
  257-  267 (22.51/15.67)	DWMNPNVSTTM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.65|      16|      19|      85|     100|       9
---------------------------------------------------------------------------
   85-  100 (28.84/19.26)	QDG.QLHRLLGKKLS..PE
  102-  120 (20.81/11.96)	QDWiQIGRKAGLALTskPK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27913 with Med8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EMMFRFMSTGMRPVEDHPGVNDWMNPNVSTTMNTSAKKTTIPASATGARRNTGPNMTTSGGTNIVTGMTTNTGASVISEVTTSAETKMVTVTDVDAKPGIDTDTNISPQMNMVPESILITGKVTPAQTPTLAQTPTPARNFITSITLAPQPSFDVTKPPPTEQANQAPPTTKEGQYPDATAIEDPNLSSSSLPGLGSNQNITRAPPPEKFCQTPLTLEEEGKDLKATPSESRQFETEISNDSDDGSSVSDLRASMATPKPSSPASPASPAS
2) GLALTSKPKNDDDDSDDDSEPEAEDEQEADDDDDDEMDEDDGDDPDSKRRKRHWAL
3) SATSNTISNDTTTTPPATIPSTLTKTKTTRSPKHPKSSKPPRAPRVSKKPKTTKKLGGTKPPNKPNQLEPLTSPSEVSLPADLDDLFKNMDDMEGLFGGV
4) SRDWDSDFTKEEIEAVGGDLTRIQTGLKTHLDGTIIKRSMDSSALSTSALNKRD
236
112
622
176
506
167
721
229










Molecular Recognition Features






MoRF SequenceStartStop




1) LDDLFK
2) PLVKFTVKSKKI
3) RRKRHWALKIVQK
4) SKKPKTTKKLGGTK
704
512
160
668
709
523
172
681