<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27909
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MAQPAEEPPLDEVLWRMPWFIQQWGQLNSNNILLYFFNSPFFDRSSNNSSLFMQTQTNPSLNHLVHNRAAFESRLKSMIGVEFVVAAEDPANAMWVIKKQMRRSPTETQLLDVYFVVGENVFMAPTMEKVMTARLLTVTSDILKAQELCSSLVHFSTEAGYTYFPPQPLQPSQTASANASFSLSGSVPPQSSAQSSVPPPPPSTLSNVPPSSVDVTITKESINMQSSLAASLRFSTVPGGYLDDNPITDPQQLMMGNSQSQGHTHSQSQSQPSLNKEKAAAREALPPVSTAAAAAAAAVAKDKGKTVSPTSPASKKRRKSKAAGLGLGP |
Length | 329 |
Position | Head |
Organism | Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) (Nematode-trapping fungus) (Didymozoophaga oligospora) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Orbiliomycetes>
Orbiliales> Orbiliaceae> Orbilia> Arthrobotrys oligospora.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.310 |
Instability index | 66.12 |
Isoelectric point | 8.59 |
Molecular weight | 35523.79 |
Publications | PubMed=21909256
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP27909
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.99| 17| 20| 156| 172| 1
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156- 172 (33.44/14.75) STEAGYTY...FPPQPLQPS
176- 195 (23.55/ 8.66) SANASFSLsgsVPPQSSAQS
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