Description | Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MSSATPAAGSSTASQSAEKVDTELRNVIQSLYEIAVSTYRNDAPNPAEIVINQVKDLVTKFDHLQTAAQGVNDLWIPREVIGYVEHGRNPDIYTREFVELAIKQNQYLNGKQHAFQDFRDVLAEHINTAFPELRGDVDEVLENTGGRRNVARLPAIASTGESGKSPAGDSAGAPASAASSVPVNGVMKMSISGSGRDEPTPTA |
Length | 203 |
Position | Middle |
Organism | Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) (Nematode-trapping fungus) (Didymozoophaga oligospora) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Orbiliomycetes> Orbiliales> Orbiliaceae> Orbilia> Arthrobotrys oligospora. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.413 |
Instability index | 44.19 |
Isoelectric point | 4.99 |
Molecular weight | 21706.75 |
Publications | PubMed=21909256 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP27902 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 122.44| 39| 158| 2| 46| 1 --------------------------------------------------------------------------- 2- 46 (59.31/45.92) SSATPAAGSSTASQSAEKvdtelrNV.IQSLYEIAVSTYRNDAPNP 162- 201 (63.13/37.08) SGKSPAGDSAGAPASAAS......SVpVNGVMKMSISGSGRDEPTP --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) RLPAIA 2) VPVNGVMKMSIS | 152 181 | 157 192 |
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