<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27890

Description Mediator complex subunit 25
SequenceMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPYLLPAVESTTYSGCTTDSLVQKIGEQGIHFSVVSPRKLPALRLLFEKAAPPSLLEPLQPPADVSQDPRHMVLVRGLVLPVGGGSAPGPLQPKQPVPLPPAPSSGAALAAPQQPLPPVPPQYQSRPSTLSSKLPREWVPPSARPLRPTPSGPPGAPKPPPASQPSLVSTVAPGAGLAPSAQPGAPSMAGTVAPGGVSGPSPAQLGTPALGGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGASGTAGQPQPQGTSQTPPGAPQGPPGAAPGPAPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPTLLPPPHQGLGQPQLGPPLLHPPPTQSWPAQLPPRAPLPAAKRKREGEGRVFREKWERDYFFVEVKSMPTCLICKKIVSVLKEYNLKRHYESKHSKSYDQYTEQTREALLNELKKGLKCQ
Length661
PositionUnknown
OrganismOryctolagus cuniculus (Rabbit)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Glires> Lagomorpha> Leporidae> Oryctolagus.
Aromaticity0.05
Grand average of hydropathy-0.438
Instability index61.52
Isoelectric point9.74
Molecular weight70736.82
Publications
PubMed=21993624

Function

Annotated function 
GO - Cellular Component
nucleoplasm	GO:0005654	IEA:Ensembl

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27890
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     218.03|      39|      65|     436|     474|       5
---------------------------------------------------------------------------
   97-  124 (44.90/11.12)	PP.S........................LLEP.............LQPP.......................ADVSQDPRHMVLV...RGL..V
  125-  185 (34.94/ 6.89)	LPVGggsapgplqpkqpvplppapssgaAL......AAPQQP...LPPV.......................PPQYQ.SRPSTLSsklPREwvP
  436-  470 (56.03/15.84)	............................ILEDQ...ARPSQNLLQLRPP.......................QPQPQGTVGASGT...AGQ..P
  471-  526 (36.81/ 7.69)	QPQGtsqtppgapqgppgaapgpappgpILRPQnpgANPQLRSLLLNPP.......................PPQT.GV..............P
  527-  578 (45.34/11.31)	PPQA.....................................SLHHLQPPgaptllppphqglgqpqlgppllHPPPTQSWPAQLP...PRA..P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.10|      15|      41|     193|     207|       6
---------------------------------------------------------------------------
  193-  207 (33.03/12.00)	PTPSG...PPGAPKPPPA
  231-  248 (24.07/ 6.37)	PSMAGtvaPGGVSGPSPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.37|      16|      24|     253|     276|       8
---------------------------------------------------------------------------
  253-  275 (20.52/23.85)	PAlggqqSV.SNKLLAWSgvLEWQ
  280-  296 (25.85/ 7.84)	PA.....SVdANTKLTRS..LPCQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27890 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GGGSAPGPLQPKQPVPLPPAPSSGAALAAPQQPLPPVPPQYQSRPSTLSSKLPREWVPPSARPLRPTPSGPPGAPKPPPASQPSLVSTVAPGAGLAPSAQPGAPSMAGTVAPGGVSGPSPAQLGTPALGG
2) HKQVQQQKLEQQRGMGAQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGASGTAGQPQPQGTSQTPPGAPQGPPGAAPGPAPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPPQASLHHLQPPGAPTLLPPPHQGLGQPQLGPPLLHPPPTQSWPAQLPPRAPLPAAKRKREGEG
128
410
257
590










Molecular Recognition Features






MoRF SequenceStartStop




NANANA