<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27850

Description Transcription elongation factor A2
SequenceSTRVGMSVNALRKQSSDEEVIALAKSLIKSWKKLLDASDAKARERGRGTPLPTSSRDASEAPDPSRKRPELPRAPSTPRITTFPPVPVTCDAVRSKCREMLAAALQTDRDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKTMTKEAIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWKFC
Length254
PositionUnknown
OrganismNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hylobatidae> Nomascus.
Aromaticity0.04
Grand average of hydropathy-0.695
Instability index50.79
Isoelectric point9.31
Molecular weight28413.20
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:InterPro
GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27850
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     194.38|      48|      48|     138|     185|       1
---------------------------------------------------------------------------
   93-  139 (57.53/30.22)	....VRSKCREMLAAALQTDRDHVA.IGADCERlsaQIEECIFRDVGNTDMK
  140-  187 (74.08/40.63)	YKNRVRSRISNLKDAKNPDLRRNVL.CGAITPQ...QIAVMTSEEMASDELK
  190-  236 (62.77/33.52)	RKTMTKEAIREHQMARTGGTQTDLFtCGKCRKK...NCTYTQVQTRSSDE..
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27850 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) SDAKARERGRGTPLPTSSRDASEAPDPSRKRPELPRAPSTPRITTFPP
38
85

Molecular Recognition Features

MoRF SequenceStartStop
1) DEEVIALAKSLIKSWKKLLDASDA
17
40