<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27832
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MCDLRRPAAGGMMDLAYVCEWEKWSKSSHCPSVPLACAWSCRNLIAFTMDLRSDDQDLTRMIHILDTEHPWDLHSIPSEHHECTLSWLLRGSVCLWGSQGGSPREPERPLPPPSLPSPQSGASSFGEKFSRVKFSPSLTLFGGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSTSPVQFYKVCVSVVSEKCRIDTEILPSLFMRCTTDLNRKDKFPAITHLKFLARDMSEQVLLCASSQTSSIVECWSLRKEGLPVNNIFQQISPVVGDKQPTILKWRILSATNDLDRVSAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAVFYSSAAPRPVDEPAVKRLRSAGPAVHFKAMQLSWTSLALVGIDSQGKLSMLRLSPSMGHPLEVGLALRHLLFLLEYCMVTGYDWWDILLHVQPSMVQSLVEKLHEEYTRQTAALQQVLSTRILAMKASLCKLSPCTVTRVCDYHTKLFLIAISSTLKSLLRPHFLNTPDKSPGDRLTEICAKITDVDIDKVMINLKTEEFVLDMNTLQALQQLLQWVGDFVLYLLAQPTQPGGSLLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTKLWICCRPSPPVDRRSCRNLASWCPGLPHALPSPARAPGQPKIDHLRRLHLGACPTEECKACTRCGCVTMLKSPNRTTAVKQWEQRWIKNCLAVEGRGPDACMTNRAAEEVPAFVQLGPRSTHRPPTTPRSLDHPHPEDRP |
Length | 806 |
Position | Tail |
Organism | Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia>
Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hylobatidae>
Nomascus.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.053 |
Instability index | 59.18 |
Isoelectric point | 8.74 |
Molecular weight | 89260.86 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP27832
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.55| 15| 95| 224| 241| 6
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224- 238 (27.25/10.71) RIDTEILPSLFMRCT
320- 334 (23.30/ 7.54) RVSAVALPKLPISLT
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 54.38| 17| 74| 521| 537| 11
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521- 537 (30.00/17.32) LFLIA.ISSTLKSLLRP.H
596- 614 (24.38/12.66) LYLLAqPTQPGGSLLRPgH
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.42| 16| 639| 30| 47| 12
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31- 47 (27.68/20.91) PSVPLAcAWSCRNLIAF
673- 688 (33.74/14.24) PSPPVD.RRSCRNLASW
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