<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27804

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVRTEIIEEAFSGMFMNTPEDEKTKLLSCLGAFRQFWGGLPPESHVQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRMVCESLINTDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLTAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICVHTGRCSLLPVVNNSGAMCNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQQKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLNLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTSCLASASITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSELQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENNIIAHFSNQGSPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRERAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREDNPWVPDDSYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDQIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSAHLNYMDPICDFLYHVKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPTTVPPQAINSGSPAPQSNQVPVSLPVTQ
Length1370
PositionTail
OrganismMyotis lucifugus (Little brown bat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Chiroptera> Microchiroptera> Vespertilionidae> Myotis.
Aromaticity0.10
Grand average of hydropathy0.000
Instability index45.86
Isoelectric point7.18
Molecular weight156533.27
Publications
PubMed=21993624

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27804
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     342.12|     103|     257|     196|     352|       3
---------------------------------------------------------------------------
  196-  303 (174.80/117.39)	LPHWLLGNLVSDFVDTFRPTARINSICVHTGRCSLLPVVNNSG.....AMCNSW.......KLDPATLRFPLKGLLPYDKDlFEPQTALLRYVLEQPYSRDMVCNMLGLNKQqkqrCPVL
  379-  493 (167.32/116.90)	LLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQsthafAMTCIWihlnrkaQNDNSKLQIPIPHSLNLHHE.FLQQSLRNKSLQMNDYKIALLCNAYSTNSE....CFTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     141.93|      45|     257|     973|    1018|       4
---------------------------------------------------------------------------
  973- 1018 (78.62/60.72)	IHRFL..eLLPVSKSLETLL..DHLGGLY..KFHDRPVTYLYN.TLHYYEMHL
 1229- 1281 (63.31/43.27)	IPKFLtevLLPIVKTEFQLLyvYHLVGPFlqRFQQERTRCMIEiGVAFYDMLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.53|      51|     257|     520|     576|       5
---------------------------------------------------------------------------
  520-  576 (73.28/64.00)	SASITPLPMNLLDSLTVHAkmSLIHSIATRVIKLAHAKSSValapALVETYSRLLVY
  784-  834 (90.25/60.63)	SNQGSPLFLCLLWKMLLET..DHINQIGYRVLERIGARALV....AHVRTFADFLVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.61|      40|     372|     918|     966|       7
---------------------------------------------------------------------------
  918-  966 (67.90/72.31)	DWHTKHMN.........YHKKYpeklYFEG..LAEQVDPPVQIQSPYLPIYfgnvcLRFL
 1284- 1334 (61.72/42.31)	DQCSAHLNymdpicdflYHVKY....MFTGdsVKEQVEKIICNLKPALKLR.....LRFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.54|      20|     785|      82|     103|      12
---------------------------------------------------------------------------
   82-  103 (33.10/21.90)	CLAMAVETGllPPRMVCESLIN
  870-  889 (38.44/20.16)	CLAMRSHEG..NEAQVCYFIIQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27804 with Med23 domain of Kingdom Metazoa
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