<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27783

Description Mediator complex subunit 24
SequenceFFLSLQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLQEGLEAGTPAAGEKQLAMCLQRLEKTLGSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTLIRSIPTMLSVHSEQPNKTGFPTVHALVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACLVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYSHGDKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDFTDFLLQECRKQGLLSEASVNNLMTKRAADREHAPQQKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGSEESTKSASVRALLFDISFLMLCHVAQTYGSEVILSESSAGAEVPFFETWIQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMNWHEACLSISAAILEILNAWENGVLAFESIQREKGREREASICCSTYLCIHWLVASVAIFKLEFNSESLSETSQTLELVLPEPQVLSPSSRVVIMSSILEHMCADVLQQTATQIKFPSTGMDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFYLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSHQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEEDANILSSPADRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLPLGRQVAAKAIAAL
Length925
PositionTail
OrganismMyotis lucifugus (Little brown bat)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Chiroptera> Microchiroptera> Vespertilionidae> Myotis.
Aromaticity0.06
Grand average of hydropathy0.015
Instability index48.72
Isoelectric point5.83
Molecular weight102766.88
Publications
PubMed=21993624

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP27783
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.78|      39|      68|     416|     457|       1
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  416-  457 (60.05/58.82)	ESTKSASVRALLFDISFLMLChvaQTYGSEVILSESSAGAEV
  485-  523 (66.72/54.96)	DSTKVESLVALLNNSSEMKLV...QMNWHEACLSISAAILEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     438.34|     181|     491|      47|     284|       2
---------------------------------------------------------------------------
   33-  282 (255.42/288.45)	LDimdmfcdrlschGKAEECIGLCR..ALLS..ALHWLLRCTAASAERLQEGlEAGTPAAGEKQLAMCLqRLEKTLGstknrallHIAKLEEASSWTAIEHSLLKLGEILANLSNPQLRSQAEQCGTL......................................................................................................................................................................................................................................................irsiptmlsvhseqpnktgfptvhalvllegtmnltgetqpLVEQLMMVKRMQH......IPTPLFVLEIWKACLVGLIESPEG..TEELKWtaFTFLKIP.QVLVKL..............KKYSHGDKDFTEDVncafEFLLKLTPL
  283-  396 (118.54/63.74)	LD....kadqrcncDFTDFLLQECRkqGLLSeaSVNNLMTKRAADREHAPQQ.KSGENANIQPNPGLIL.RAEPTVT........NILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKL...........................................................................................................................................................................................................................................................................................................................................................................................................
  684-  785 (64.38/23.11)	................................................................................................................................ksfarkfinlneftthgseestksasvrallfdisflmlchvaqtygsevilsessagaevpffetwiqtcmpeegkilnpdhpcfrpdstkveslvallnnssemklvqmnwheaclsisaaileilnawengvlafesiqrekgrereasiccstylcihwlvasvaifklefnseslsetsqtlelvlpepqvlspssrvvimssilehmcadvlqqtatqikfpstgmdtmpywnllppkrpikevltdifakvlekgwvdsrsihifdtllhmggvywfcnnLIKELLKETRKEHtlraveLLYSIFYLDMQQVTLVLLGHILPGllTDSSKW..HSLMDPPgTALAKLavwcalssysshkgQASSHQKKRHREDI....EDYISLFPL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP27783 with Med24 domain of Kingdom Metazoa
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