<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27761

Description Transcription elongation factor A1
SequenceAGALDLLKELKNIPMTLELLQTTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRVKCREMLSAALRTGDDYIAIGADEEELGSQIESKAPIFQELKNTDMKYKNRVRSRIANLKDAKNPNLRKNVLCGNIPPDKFAKMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
Length283
PositionUnknown
OrganismMeleagris gallopavo (Wild turkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Phasianidae> Meleagridinae> Meleagris.
Aromaticity0.04
Grand average of hydropathy-0.819
Instability index52.54
Isoelectric point8.79
Molecular weight31462.29
Publications
PubMed=20838655

Function

Annotated function
GO - Cellular Component
nucleolus	GO:0005730	IEA:Ensembl
transcription factor TFIID complex	GO:0005669	IEA:Ensembl
GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27761
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.80|      27|      48|     166|     195|       1
---------------------------------------------------------------------------
  165-  191 (42.52/23.62)	TDMKYKNRVRSRIANLKDAKNPNLRKN
  195-  221 (42.28/32.74)	GNIPPDKFAKMTAEEMASDELKEMRKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.15|      22|      27|      64|      90|       2
---------------------------------------------------------------------------
   57-   79 (32.00/13.16)	DGPSTDKDSEEKKKEPASSSqNS
   84-  105 (36.15/19.70)	EESSSSSNSSSRKEEGSAPS.NS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.45|      14|      27|     240|     253|       3
---------------------------------------------------------------------------
  240-  253 (28.18/20.15)	TDLFTCGKC..KKKNC
  268-  283 (25.27/17.35)	TTFVVCNECgnRWKFC
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27761 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LLDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRVKCRE
55
126

Molecular Recognition Features

MoRF SequenceStartStop
1) LAKSLIKSWKKLLD
44
57