<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP27747

Description Uncharacterized protein
SequenceIHNMVAVLEVISSLEKYPITKEALEETRLGRLINEVRKKTSNEELAKRAKKLLRNWQKLIEPVTPNEAVPRGLQNPPGSANGGAHNCKPEAPLPAVAGSKPISELKSRNDIQKLNSPKPEKLGNRKRKGEHRDGHQGPPPPKVSKVSHEILQNSSPPPTNGIGGSPENFPSPVDVNLHAGPESSRTELSENDKHNKIPVNAVKPHTSSPGLVKPSSTSSLLKTAVLQQHDKSEETSGSHQPKSPRCSSFSPRNVRHDAFARQHTTYSPKDSMPSPSQRSQFLDTAQVPSPPPSLMQPSTPPMPAKRLEFSQQSVSEVSQHWQEQQVPSDSQHRHTAGTLPQHTSPTCKTSSHPGESLVSHIGFSQDASKMDSDDAASGSDSKKKKRYRPRDYTVNLDGHVTEGGVKPVRLKERKLTFDPMTGQIKPLTPKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRKEARKTHVLAPNSKPTDLPGVTREVTSDDLDRIREHNWPGVNGCFDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length589
PositionUnknown
OrganismMeleagris gallopavo (Wild turkey)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Galloanserae> Galliformes> Phasianidae> Meleagridinae> Meleagris.
Aromaticity0.04
Grand average of hydropathy-0.987
Instability index62.02
Isoelectric point8.93
Molecular weight65368.19
Publications
PubMed=20838655

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP27747
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     542.67|     139|     149|      74|     222|       1
---------------------------------------------------------------------------
   74-  208 (208.69/86.77)	....................QNPPGSANGGAHncKPEAPlpavAGSKPISELKSRNDI...QKLN.SPKPEKLGNRKRKGEHR........DGHQGP.PPPKVSKVSHEILQNSSPP.PTNGIGGSPENFPSPVDVNLHAGPESSRTELSENDKHNKIPVNAVKPHTSS
  209-  337 (172.52/66.71)	PGLVKPS.STSsllktavlqQHDKSEETSGSH..QPKSP.....RCSSFSPRNVRHDAfarQHTTySPK.DSMPSPSQRSQFL........DTAQVPsPPP.......SLMQPSTPPmPAKRLEFSQQ................SVSEVSQHWQEQQVPSDSQHRHTAG
  340-  459 (161.46/59.03)	PQHTSPTcKTS..............................shPGESLVSHIGFSQDA...SKMD.SDDAASGSDSKKKKRYRprdytvnlDGHVTE.GGVKPVRLKERKL..TFDP.MTGQI..KPLTPKDPLQVEIPALTEQHRT...ETEKQEQ......KPNLQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.69|      15|      35|     481|     495|       2
---------------------------------------------------------------------------
  481-  495 (25.43/13.18)	RQSSLL..SSSGVQTPG
  515-  531 (22.26/10.68)	RKTHVLapNSKPTDLPG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP27747 with Med26 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) RNWQKLIEPVTPNEAVPRGLQNPPGSANGGAHNCKPEAPLPAVAGSKPISELKSRNDIQKLNSPKPEKLGNRKRKGEHRDGHQGPPPPKVSKVSHEILQNSSPPPTNGIGGSPENFPSPVDVNLHAGPESSRTELSENDKHNKIPVNAVKPHTSSPGLVKPSSTSSLLKTAVLQQHDKSEETSGSHQPKSPRCSSFSPRNVRHDAFARQHTTYSPKDSMPSPSQRSQFLDTAQVPSPPPSLMQPSTPPMPAKRLEFSQQSVSEVSQHWQEQQVPSDSQHRHTAGTLPQHTSPTCKTSSHPGESLVSHIGFSQDASKMDSDDAASGSDSKKKKRYRPRDYTVNLDGHVTEGGVKPVRLKERKLTFDPMTGQIKPLTPKDPLQVEIPALTEQHRTETEKQEQKPNLQSPFEQTNW
2) TRKEARKTHVLAPNSKPTDLPGVTREVTSDDLDRI
54
510
466
544

Molecular Recognition Features

MoRF SequenceStartStop
1) KKKKRYRPRDYTVNL
382
396